Understanding the Effect of Non-natural Fluid Environments on Enzyme Stability

Project Information

FLUIZYME

Grant agreement ID: 101021024

DOI 10.3030/101021024

EC signature date 5 July 2021

Start date 1 October 2021

End date 30 September 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 352 846,00

EU contribution € 2 352 846,00

Coordinated by

DANMARKS TEKNISKE UNIVERSITET
Denmark

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan (DMP)

This deliverable will provide a plan for the way in which data from the experimental work in the project is to be collated and stored The plan should provide an easily accessible way to correlate experimental conditions also including spatial and temporal conditions with enzyme stability The data is of particular importance since it is completely new There will also be interest in access to such data from those working on ML algorithms

Publications

Peer reviewed articles (11)

Effect of Nitrogen, Air, and Oxygen on the Kinetic Stability of NAD(P)H Oxidase Exposed to a Gas–Liquid Interface

Author(s): Jingyu Wang, Elif Erdem, and John M. Woodley
Published in: Org. Process Res. Dev., 2023, ISSN 1520-586X
Publisher: American Chemical Society
DOI: 10.1021/acs.oprd.3c00095

Co-Enzymes with Dissimilar Stabilities: A Discussion of the Likely Biocatalyst Performance Problems and Some Potential Solutions

Author(s): Amalie Vang Høst,Roberto Morellon-Sterling,Diego Carballares,John M. Woodley and Roberto Fernandez-Lafuente
Published in: Catalyst, 2022, ISSN 2073-4344
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal12121570

Mass-based biocatalyst metrics to guide protein engineering and bioprocess development

Author(s): Murray P. Meissner, John M. Woodley
Published in: Nature Catalysis, Issue 5, 2022, Page(s) 2-4, ISSN 2520-1158
Publisher: Springer
DOI: 10.1038/s41929-021-00728-5

Modeling and tuning of glucose oxidase‐catalase system incorporating dissolved oxygen concentration

Author(s): Angela V. Ruales‐Salcedo, Oscar Andrés Prado‐Rubio, Javier Fontalvo, Juan Carlos Higuita, John M. Woodley
Published in: Journal of Chemical Technology & Biotechnology, Issue 98, 2023, Page(s) 1520-1531, ISSN 0268-2575
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jctb.7374

Industrially useful enzymology: Translating biocatalysis from laboratory to process

Author(s): Elif Erdem, John M Woodley
Published in: Chem Catalysis, 2022, ISSN 2667-1093
Publisher: Elsevier
DOI: 10.1016/j.checat.2022.09.037

Toward Kilogram-Scale Peroxygenase-Catalyzed Oxyfunctionalization of Cyclohexane

Author(s): Thomas Hilberath; Remco van Oosten; Juliet Victoria; Hugo Brasselet; Miguel Alcalde; John M. Woodley; Frank Hollmann
Published in: Org. Process Res. Dev., 2023, ISSN 1520-586X
Publisher: American Chemical Society
DOI: 10.1021/acs.oprd.3c00135

Raman spectroscopy and one‐dimensional convolutional neural network modeling as a real‐time monitoring tool for in vitro transaminase‐catalyzed synthesis of a pharmaceutically relevant amine precursor

Author(s): Julie Østerby Madsen, Sebastian Olivier Nymann Topalian, Mikkel Fog Jacobsen, Tommy Skovby, Krist V. Gernaey, Allan S. Myerson, John Woodley
Published in: Biotechnology Progress, Issue 40, 2024, ISSN 8756-7938
Publisher: American Chemical Society
DOI: 10.1002/btpr.3444

Is enzyme immobilization a mature discipline? Some critical considerations to capitalize on the benefits of immobilization

Author(s): Juan M. Bolivar; John M. Woodley; Roberto Fernandez-Lafuente
Published in: Chemical Society Reviews, 2022, ISSN 0306-0012
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2cs00083k

Ensuring the Sustainability of Biocatalysis

Author(s): John M. Woodley
Published in: ChemSusChem, 2022, ISSN 1864-5631
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.202102683

New Horizons for Biocatalytic Science

Author(s): John M. Woodley
Published in: Fontiers in Catalysis, 2022, ISSN 2673-7841
Publisher: Frontiers
DOI: 10.3389/fctls.2022.883161

Considerations for the Scale‐up of <i>in vitro</i> Transaminase‐Catalyzed Asymmetric Synthesis of Chiral Amines

Author(s): Julie Østerby Madsen, John M. Woodley
Published in: ChemCatChem, Issue 15, 2023, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202300560