Understanding the Effect of Non-natural Fluid Environments on Enzyme Stability

Informazioni relative al progetto

FLUIZYME

ID dell’accordo di sovvenzione: 101021024

DOI

10.3030/101021024

Data della firma CE 5 Luglio 2021

Data di avvio 1 Ottobre 2021

Data di completamento 30 Settembre 2026

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 2 352 846,00

Contributo UE

€ 2 352 846,00

Coordinato da

DANMARKS TEKNISKE UNIVERSITET
Denmark

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Open Research Data Pilot (1)

Data Management Plan (DMP)

This deliverable will provide a plan for the way in which data from the experimental work in the project is to be collated and stored The plan should provide an easily accessible way to correlate experimental conditions also including spatial and temporal conditions with enzyme stability The data is of particular importance since it is completely new There will also be interest in access to such data from those working on ML algorithms

Pubblicazioni

Peer reviewed articles (11)

Effect of Nitrogen, Air, and Oxygen on the Kinetic Stability of NAD(P)H Oxidase Exposed to a Gas–Liquid Interface

Autori: Jingyu Wang, Elif Erdem, and John M. Woodley
Pubblicato in: Org. Process Res. Dev., 2023, ISSN 1520-586X
Editore: American Chemical Society
DOI: 10.1021/acs.oprd.3c00095

Co-Enzymes with Dissimilar Stabilities: A Discussion of the Likely Biocatalyst Performance Problems and Some Potential Solutions

Autori: Amalie Vang Høst,Roberto Morellon-Sterling,Diego Carballares,John M. Woodley and Roberto Fernandez-Lafuente
Pubblicato in: Catalyst, 2022, ISSN 2073-4344
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal12121570

Mass-based biocatalyst metrics to guide protein engineering and bioprocess development

Autori: Murray P. Meissner, John M. Woodley
Pubblicato in: Nature Catalysis, Numero 5, 2022, Pagina/e 2-4, ISSN 2520-1158
Editore: Springer
DOI: 10.1038/s41929-021-00728-5

Modeling and tuning of glucose oxidase‐catalase system incorporating dissolved oxygen concentration

Autori: Angela V. Ruales‐Salcedo, Oscar Andrés Prado‐Rubio, Javier Fontalvo, Juan Carlos Higuita, John M. Woodley
Pubblicato in: Journal of Chemical Technology & Biotechnology, Numero 98, 2023, Pagina/e 1520-1531, ISSN 0268-2575
Editore: John Wiley & Sons Inc.
DOI: 10.1002/jctb.7374

Industrially useful enzymology: Translating biocatalysis from laboratory to process

Autori: Elif Erdem, John M Woodley
Pubblicato in: Chem Catalysis, 2022, ISSN 2667-1093
Editore: Elsevier
DOI: 10.1016/j.checat.2022.09.037

Toward Kilogram-Scale Peroxygenase-Catalyzed Oxyfunctionalization of Cyclohexane

Autori: Thomas Hilberath; Remco van Oosten; Juliet Victoria; Hugo Brasselet; Miguel Alcalde; John M. Woodley; Frank Hollmann
Pubblicato in: Org. Process Res. Dev., 2023, ISSN 1520-586X
Editore: American Chemical Society
DOI: 10.1021/acs.oprd.3c00135

Raman spectroscopy and one‐dimensional convolutional neural network modeling as a real‐time monitoring tool for in vitro transaminase‐catalyzed synthesis of a pharmaceutically relevant amine precursor

Autori: Julie Østerby Madsen, Sebastian Olivier Nymann Topalian, Mikkel Fog Jacobsen, Tommy Skovby, Krist V. Gernaey, Allan S. Myerson, John Woodley
Pubblicato in: Biotechnology Progress, Numero 40, 2024, ISSN 8756-7938
Editore: American Chemical Society
DOI: 10.1002/btpr.3444

Is enzyme immobilization a mature discipline? Some critical considerations to capitalize on the benefits of immobilization

Autori: Juan M. Bolivar; John M. Woodley; Roberto Fernandez-Lafuente
Pubblicato in: Chemical Society Reviews, 2022, ISSN 0306-0012
Editore: Royal Society of Chemistry
DOI: 10.1039/d2cs00083k

Ensuring the Sustainability of Biocatalysis

Autori: John M. Woodley
Pubblicato in: ChemSusChem, 2022, ISSN 1864-5631
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.202102683

New Horizons for Biocatalytic Science

Autori: John M. Woodley
Pubblicato in: Fontiers in Catalysis, 2022, ISSN 2673-7841
Editore: Frontiers
DOI: 10.3389/fctls.2022.883161

Considerations for the Scale‐up of <i>in vitro</i> Transaminase‐Catalyzed Asymmetric Synthesis of Chiral Amines

Autori: Julie Østerby Madsen, John M. Woodley
Pubblicato in: ChemCatChem, Numero 15, 2023, ISSN 1867-3880
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202300560