Understanding the Effect of Non-natural Fluid Environments on Enzyme Stability

Información del proyecto

FLUIZYME

Identificador del acuerdo de subvención: 101021024

DOI

10.3030/101021024

Fecha de la firma de la CE 5 Julio 2021

Fecha de inicio 1 Octubre 2021

Fecha de finalización 30 Septiembre 2026

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 352 846,00

Aportación de la UE

€ 2 352 846,00

Coordinado por

DANMARKS TEKNISKE UNIVERSITET
Denmark

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Open Research Data Pilot (1)

Data Management Plan (DMP)

This deliverable will provide a plan for the way in which data from the experimental work in the project is to be collated and stored The plan should provide an easily accessible way to correlate experimental conditions also including spatial and temporal conditions with enzyme stability The data is of particular importance since it is completely new There will also be interest in access to such data from those working on ML algorithms

Publicaciones

Peer reviewed articles (11)

Effect of Nitrogen, Air, and Oxygen on the Kinetic Stability of NAD(P)H Oxidase Exposed to a Gas–Liquid Interface

Autores: Jingyu Wang, Elif Erdem, and John M. Woodley
Publicado en: Org. Process Res. Dev., 2023, ISSN 1520-586X
Editor: American Chemical Society
DOI: 10.1021/acs.oprd.3c00095

Co-Enzymes with Dissimilar Stabilities: A Discussion of the Likely Biocatalyst Performance Problems and Some Potential Solutions

Autores: Amalie Vang Høst,Roberto Morellon-Sterling,Diego Carballares,John M. Woodley and Roberto Fernandez-Lafuente
Publicado en: Catalyst, 2022, ISSN 2073-4344
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal12121570

Mass-based biocatalyst metrics to guide protein engineering and bioprocess development

Autores: Murray P. Meissner, John M. Woodley
Publicado en: Nature Catalysis, Edición 5, 2022, Página(s) 2-4, ISSN 2520-1158
Editor: Springer
DOI: 10.1038/s41929-021-00728-5

Modeling and tuning of glucose oxidase‐catalase system incorporating dissolved oxygen concentration

Autores: Angela V. Ruales‐Salcedo, Oscar Andrés Prado‐Rubio, Javier Fontalvo, Juan Carlos Higuita, John M. Woodley
Publicado en: Journal of Chemical Technology & Biotechnology, Edición 98, 2023, Página(s) 1520-1531, ISSN 0268-2575
Editor: John Wiley & Sons Inc.
DOI: 10.1002/jctb.7374

Industrially useful enzymology: Translating biocatalysis from laboratory to process

Autores: Elif Erdem, John M Woodley
Publicado en: Chem Catalysis, 2022, ISSN 2667-1093
Editor: Elsevier
DOI: 10.1016/j.checat.2022.09.037

Toward Kilogram-Scale Peroxygenase-Catalyzed Oxyfunctionalization of Cyclohexane

Autores: Thomas Hilberath; Remco van Oosten; Juliet Victoria; Hugo Brasselet; Miguel Alcalde; John M. Woodley; Frank Hollmann
Publicado en: Org. Process Res. Dev., 2023, ISSN 1520-586X
Editor: American Chemical Society
DOI: 10.1021/acs.oprd.3c00135

Raman spectroscopy and one‐dimensional convolutional neural network modeling as a real‐time monitoring tool for in vitro transaminase‐catalyzed synthesis of a pharmaceutically relevant amine precursor

Autores: Julie Østerby Madsen, Sebastian Olivier Nymann Topalian, Mikkel Fog Jacobsen, Tommy Skovby, Krist V. Gernaey, Allan S. Myerson, John Woodley
Publicado en: Biotechnology Progress, Edición 40, 2024, ISSN 8756-7938
Editor: American Chemical Society
DOI: 10.1002/btpr.3444

Is enzyme immobilization a mature discipline? Some critical considerations to capitalize on the benefits of immobilization

Autores: Juan M. Bolivar; John M. Woodley; Roberto Fernandez-Lafuente
Publicado en: Chemical Society Reviews, 2022, ISSN 0306-0012
Editor: Royal Society of Chemistry
DOI: 10.1039/d2cs00083k

Ensuring the Sustainability of Biocatalysis

Autores: John M. Woodley
Publicado en: ChemSusChem, 2022, ISSN 1864-5631
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.202102683

New Horizons for Biocatalytic Science

Autores: John M. Woodley
Publicado en: Fontiers in Catalysis, 2022, ISSN 2673-7841
Editor: Frontiers
DOI: 10.3389/fctls.2022.883161

Considerations for the Scale‐up of <i>in vitro</i> Transaminase‐Catalyzed Asymmetric Synthesis of Chiral Amines

Autores: Julie Østerby Madsen, John M. Woodley
Publicado en: ChemCatChem, Edición 15, 2023, ISSN 1867-3880
Editor: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202300560