Electrochemical Bond Functionalization

Información del proyecto

ElectroFun

Identificador del acuerdo de subvención: 101021358

DOI

10.3030/101021358

Fecha de la firma de la CE 28 Julio 2021

Fecha de inicio 1 Agosto 2021

Fecha de finalización 31 Julio 2026

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 499 423,75

Aportación de la UE

€ 2 499 423,75

Coordinado por

GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (42)

Direct Synthesis of C4-Acyl Indoles via C–H Acylation

Autores: Bo-Sheng Zhang, Ze-Qiang Zhang, Tian-Jiao Guo, João C. A. Oliveira, Svenja Warratz, Bao-Jie Deng, Yi-Ming Wang, Jun-Shi Zhou, Xue-Ya Gou, Xi-Cun Wang, Zheng-Jun Quan, Lutz Ackermann
Publicado en: Organic Letters, Edición 26, 2024, Página(s) 4998-5003, ISSN 1523-7060
Editor: American Chemical Society
DOI: 10.1021/acs.orglett.4c01658

Close‐Shell Reductive Elimination versus Open‐Shell Radical Coupling for Site‐Selective Ruthenium‐Catalyzed C−H Activations by Computation and Experiments

Autores: Xinran Chen, Hasret Can Gülen, Jun Wu, Zi‐Jing Zhang, Xin Hong, Lutz Ackermann
Publicado en: Angewandte Chemie International Edition, Edición 62, 2023, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202302021

Manganese(I)-Catalyzed C–H Allylation of Tryptophans and Their Oligopeptides On Water

Autores: Fabrice Gallou, Lutz Ackermann, Julia Struwe, Tsuyoshi Oyama
Publicado en: Synlett, Edición 35, 2024, Página(s) 903-907, ISSN 0936-5214
Editor: Georg Thieme Verlag
DOI: 10.1055/a-2268-4678

Site-selective electrochemical carboxylation of aromatic C(sp2)–H bonds with CO2

Autores: Rong Zhao, Max Surke, Zhipeng Lin, Ali Alsalme, Lutz Ackermann
Publicado en: Current Research in Green and Sustainable Chemistry, Edición 7, 2024, Página(s) 100377, ISSN 2666-0865
Editor: Elsevier
DOI: 10.1016/j.crgsc.2023.100377

Radical cascade cyclization of 1,<i>n</i>-enynes under photo/electrochemical conditions

Autores: Zhenzhi Cai, Sven Trienes, Kairui Liu, Lutz Ackermann, Yan Zhang
Publicado en: Organic Chemistry Frontiers, Edición 10, 2024, Página(s) 5735-5745, ISSN 2052-4129
Editor: Royal Society of Chemistry
DOI: 10.1039/d3qo01482g

Enantioselective electrochemical cobalt-catalyzed aryl C–H activation reactions

Autores: Tristan von Münchow, Suman Dana, Yang Xu, Binbin Yuan, Lutz Ackermann
Publicado en: Science, Edición 379, 2024, Página(s) 1036-1042, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.adg2866

Metallaelectro-catalyzed alkyne annulations <i>via</i> C–H activations for sustainable heterocycle syntheses

Autores: Preeti Kushwaha, Anjali Saxena, Tristan von Münchow, Suman Dana, Biswajit Saha, Lutz Ackermann
Publicado en: Chemical Communications, 2024, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/d4cc03871a

Machine learning-guided yield optimization for palladaelectro-catalyzed annulation reaction

Autores: Xiaoyan Hou, Shuwen Li, Johanna Frey, Xin Hong, Lutz Ackermann
Publicado en: Chem, Edición 10, 2024, Página(s) 2283-2294, ISSN 2451-9294
Editor: Elsevier
DOI: 10.1016/j.chempr.2024.03.027

Combined C-H amination and intermolecular alkyne insertion for a three-component cyclization

Autores: Bo-Sheng Zhang, Yu-Xi Yang, João C.A. Oliveira, Ze-Qiang Zhang, Svenja Warratz, Yi-Ming Wang, Shun-Xi Li, Xi-Cun Wang, Xue-Ya Gou, Yong-Min Liang, Zheng-Jun Quan, Lutz Ackermann
Publicado en: Cell Reports Physical Science, Edición 4, 2023, Página(s) 101647, ISSN 2666-3864
Editor: Elsevier
DOI: 10.1016/j.xcrp.2023.101647

Electrochemical C7‐Indole Alkenylation <i>via</i> Rhodium Catalysis

Autores: Agnese Zangarelli, Binbin Yuan, Lutz Ackermann
Publicado en: Israel Journal of Chemistry, Edición 64, 2024, ISSN 0021-2148
Editor: Laser Pages Publishing Ltd.
DOI: 10.1002/ijch.202300103

Template Synthesis to Solve the Unreachable <i>Ortho</i> C–H Functionalization Reaction of Aryl Iodide

Autores: Bo-Sheng Zhang, Wan-Yuan Jia, Yi-Ming Wang, João C. A. Oliveira, Svenja Warratz, Ze-Qiang Zhang, Xue-Ya Gou, Yong-Min Liang, Xi-Cun Wang, Zheng-Jun Quan, Lutz Ackermann
Publicado en: The Journal of Organic Chemistry, Edición 88, 2023, Página(s) 16539-16546, ISSN 0022-3263
Editor: American Chemical Society
DOI: 10.1021/acs.joc.3c02014

Photoinduced C–H arylation of 1,3-azoles <i>via</i> copper/photoredox dual catalysis

Autores: Sven Trienes, Jiawei Xu, Lutz Ackermann
Publicado en: Chemical Science, Edición 15, 2024, Página(s) 7293-7299, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/d4sc00393d

Weak-coordination-auxiliary aminocatalysis enables directed [3 + 2] cyclization for 2-acylindolizines

Autores: Kui Zeng, Neeraj Kumar Pandit, João C. A. Oliveira, Sebastian Dechert, Lutz Ackermann, Kai Zhang
Publicado en: Green Chemistry, Edición 26, 2024, Página(s) 5253-5259, ISSN 1463-9262
Editor: Royal Society of Chemistry
DOI: 10.1039/d3gc03552b

Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification

Autores: Zhipeng Lin, Uttam Dhawa, Xiaoyan Hou, Max Surke, Binbin Yuan, Shu-Wen Li, Yan-Cheng Liou, Magnus J. Johansson, Li-Cheng Xu, Chen-Hang Chao, Xin Hong, Lutz Ackermann
Publicado en: Nature Communications, Edición 14, 2023, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-023-39747-0

Late-stage synthesis of heterobifunctional molecules for PROTAC applications via ruthenium-catalysed C‒H amidation

Autores: Daniele Antermite, Stig D. Friis, Johan R. Johansson, Okky Dwichandra Putra, Lutz Ackermann, Magnus J. Johansson
Publicado en: Nature Communications, Edición 14, 2023, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-023-43789-9

Photoelectrochemical Iron-Catalyzed C(sp ³ )–H Borylation of Alkanes in a Position-Selective Manner

Autores: Wen Wei, Bin Wang, Simon L. Homölle, Jinbin Zhu, Yanjun Li, Tristan von Münchow, Isaac Maksso, Lutz Ackermann
Publicado en: CCS Chemistry, Edición 6, 2024, Página(s) 1430-1438, ISSN 2096-5745
Editor: Chinese Chemical Society
DOI: 10.31635/ccschem.024.202403894

Photoelectrochemical Si–H and Ge–H activation by iron catalysis

Autores: Wen Wei, Simon L. Homölle, Tristan von Münchow, Yanjun Li, Isaac Maksso, Lutz Ackermann
Publicado en: Cell Reports Physical Science, Edición 4, 2024, Página(s) 101550, ISSN 2666-3864
Editor: Elsevier
DOI: 10.1016/j.xcrp.2023.101550

Nickel-Catalyzed Atroposelective C–H Alkylation Enabled by Bimetallic Catalysis with Air-Stable Heteroatom-Substituted Secondary Phosphine Oxide Preligands

Autores: Zi-Jing Zhang, Matthias M. Simon, Shuang Yu, Shu-Wen Li, Xinran Chen, Silvia Cattani, Xin Hong, Lutz Ackermann
Publicado en: Journal of the American Chemical Society, Edición 146, 2024, Página(s) 9172-9180, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.3c14600

Anodic Commodity Polymer Recycling: The Merger of Iron‐Electrocatalysis with Scalable Hydrogen Evolution Reaction

Autores: Maxime Hourtoule, Sven Trienes, Lutz Ackermann
Publicado en: Angewandte Chemie International Edition, 2024, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202412689

Electrochemical Late-Stage Functionalization

Autores: Yulei Wang, Suman Dana, Hao Long, Yang Xu, Yanjun Li, Nikolaos Kaplaneris, Lutz Ackermann
Publicado en: Chemical Reviews, Edición 123, 2023, Página(s) 11269-11335, ISSN 0009-2665
Editor: American Chemical Society
DOI: 10.1021/acs.chemrev.3c00158

The crucial role of silver(<scp>i</scp>)-salts as additives in C–H activation reactions: overall analysis of their versatility and applicability

Autores: Renato L. de Carvalho, Emilay B. T. Diogo, Simon L. Homölle, Suman Dana, Eufrânio N. da Silva Júnior, Lutz Ackermann
Publicado en: Chemical Society Reviews, Edición 52, 2024, Página(s) 6359-6378, ISSN 0306-0012
Editor: Royal Society of Chemistry
DOI: 10.1039/d3cs00328k

Electrochemical Syntheses of Polycyclic Aromatic Hydrocarbons (PAHs)

Autores: Yulei Wang, Rong Zhao, Lutz Ackermann
Publicado en: Advanced Materials, Edición 35, 2024, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202300760

Bifurcated Rhodaelectro-catalyzed C–H Activation for the Synthesis of Pyrroles and Lactones

Autores: Simon L. Homölle, Maximilian Stangier, Efraim Reyes, Lutz Ackermann
Publicado en: Precision Chemistry, Edición 1, 2023, Página(s) 382-387, ISSN 2771-9316
Editor: American Chemical Society
DOI: 10.1021/prechem.3c00061

Polymer up-cycling by mangana-electrocatalytic C(sp³)–H azidation without directing groups

Autores: Isaac Maksso, Ramesh C. Samanta, Yifei Zhan, Kai Zhang, Svenja Warratz, Lutz Ackermann
Publicado en: Chemical Science, Edición 14, 2024, Página(s) 8109-8118, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/d3sc02549g

Electrocatalytic Formal C(sp²)−H Alkylations via Nickel‐Catalyzed Cross‐Electrophile Coupling with Versatile Arylsulfonium Salts

Autores: Takuya Michiyuki, Simon L. Homölle, Neeraj K. Pandit, Lutz Ackermann
Publicado en: Angewandte Chemie International Edition, Edición 63, 2024, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202401198

Electrochemical Rearrangement for Remote Functionalizations of Unactivated Alkenes

Autores: Dingyi Wang, Binbin Yuan, Jiawei Xu, Lutz Ackermann
Publicado en: Chemistry – A European Journal, Edición 29, 2024, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202300600

Electrochemical Sulphenylation/Cyclization of Quinones: A Rapid, Green, and Efficient Access to Cytotoxic Compounds

Autores: Emilay B. T. Diogo, Fábio G. Delolo, Gabriela A. P. Graça, Esther R. S. Paz, Ícaro A. O. Bozzi, Renata Diniz, Juliano P. Passos, Tulio Matencio, Liane K. Soares, Diego Alves, Pedro M. S. Costa, Claudia Pessoa, Cynthia L. M. Pereira, Lutz Ackermann, Eufrânio N. da Silva Júnior
Publicado en: European Journal of Organic Chemistry, Edición 26, 2023, ISSN 1434-193X
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202300506

Cobaltaelectro-Catalyzed C–H Annulation with Allenes for Atropochiral and <i>P</i>-Stereogenic Compounds: Late-Stage Diversification and Continuous Flow Scale-Up

Autores: Ye Lin, Tristan von Münchow, Lutz Ackermann
Publicado en: ACS Catalysis, Edición 13, 2023, Página(s) 9713-9723, ISSN 2155-5435
Editor: American Chemical Society
DOI: 10.1021/acscatal.3c02072

Photoelectrocatalytic [4+2] Annulation for <i>S</i>‐Heterocycle Assembly Enabled by Proton‐Coupled Electron Transfer (PCET)

Autores: Yuan‐Yuan Cheng, Jiawei Xu, Zhipeng Lin, Yanjun Li, Lutz Ackermann
Publicado en: Chemistry – A European Journal, 2024, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202402333

Recent advances in organic electrochemical functionalizations for specialty chemicals

Autores: Yanjun Li, Suman Dana, Lutz Ackermann
Publicado en: Current Opinion in Electrochemistry, Edición 40, 2024, Página(s) 101312, ISSN 2451-9103
Editor: Elsevier
DOI: 10.1016/j.coelec.2023.101312

Photo‐Induced Ruthenium‐Catalyzed C−H Arylation Polymerization at Ambient Temperature

Autores: Takuya Michiyuki, Isaac Maksso, Lutz Ackermann
Publicado en: Angewandte Chemie International Edition, Edición 63, 2024, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202400845

Room temperature photo-promoted iron-catalysed arene C–H alkenylation without Grignard reagents

Autores: Antonis M. Messinis, Tristan von Münchow, Max Surke, Lutz Ackermann
Publicado en: Nature Catalysis, Edición 7, 2024, Página(s) 273-284, ISSN 2520-1158
Editor: Springer Nature
DOI: 10.1038/s41929-023-01105-0

Electrochemical assembly of isoxazoles <i>via</i> a four-component domino reaction

Autores: Yuanyuan Zhao, Xinyue Li, Simon L. Homölle, Bin Wang, Lutz Ackermann
Publicado en: Chemical Science, Edición 15, 2024, Página(s) 1117-1122, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/d3sc05946d

Cobaltaelectro‐Catalyzed C–H Activation for Central and Axial Double Enantio‐Induction

Autores: Tristan von Münchow, Yi‐Ru Liu, Rahul Parmar, Sven Erik Peters, Sven Trienes, Lutz Ackermann
Publicado en: Angewandte Chemie International Edition, Edición 63, 2024, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202405423

Electrochemical Glycosylation via Halogen-Atom-Transfer for <i>C</i>-Glycoside Assembly

Autores: Jun Wu, Rajeshwaran Purushothaman, Felix Kallert, Simon L. Homölle, Lutz Ackermann
Publicado en: ACS Catalysis, Edición 14, 2024, Página(s) 11532-11544, ISSN 2155-5435
Editor: American Chemical Society
DOI: 10.1021/acscatal.4c02322

Electrochemical Skeletal Indole Editing via Nitrogen Atom Insertion by Sustainable Oxygen Reduction Reaction

Autores: Bo‐Sheng Zhang, Simon L. Homölle, Tristan Bauch, João C. A. Oliveira, Svenja Warratz, Binbin Yuan, Xue‐Ya Gou, Lutz Ackermann
Publicado en: Angewandte Chemie International Edition, 2024, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202407384

Chelation-Assisted Iron-Catalyzed C–H Activations: Scope and Mechanism

Autores: Jiayu Mo, Antonis M. Messinis, Jinlian Li, Svenja Warratz, Lutz Ackermann
Publicado en: Accounts of Chemical Research, Edición 57, 2024, Página(s) 10-22, ISSN 0001-4842
Editor: American Chemical Society
DOI: 10.1021/acs.accounts.3c00294

Enantioselective Cobaltaphotoredox-Catalyzed C–H Activation

Autores: Yang Xu, Ye Lin, Simon L. Homölle, João C. A. Oliveira, Lutz Ackermann
Publicado en: Journal of the American Chemical Society, Edición 146, 2024, Página(s) 24105-24113, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.4c08459

Data-driven design of new chiral carboxylic acid for construction of indoles with C-central and C–N axial chirality via cobalt catalysis

Autores: Zi-Jing Zhang, Shu-Wen Li, João C. A. Oliveira, Yanjun Li, Xinran Chen, Shuo-Qing Zhang, Li-Cheng Xu, Torben Rogge, Xin Hong, Lutz Ackermann
Publicado en: Nature Communications, Edición 14, 2023, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-023-38872-0

Electrochemical Enantioselective C–H Annulation by Achiral Rhodium(III)/Chiral Brønsted Base Domino Catalysis

Autores: Yanjun Li, Jiawei Xu, João C. A. Oliveira, Alexej Scheremetjew, Lutz Ackermann
Publicado en: ACS Catalysis, Edición 14, 2024, Página(s) 8160-8167, ISSN 2155-5435
Editor: American Chemical Society
DOI: 10.1021/acscatal.4c01886

Well‐Defined Highly‐Coordinated Copper(III) Iodide and Pincer Tris(trifluoromethyl)copper Complexes

Autores: Vladimir Motornov, Lutz Ackermann
Publicado en: Chemistry – A European Journal, 2024, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202401791

Palladium-Catalyzed Electrooxidative Double C–H Arylation

Autores: Zhipeng Lin, João C. A. Oliveira, Alexej Scheremetjew, Lutz Ackermann
Publicado en: Journal of the American Chemical Society, Edición 146, 2024, Página(s) 228-239, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.3c08479