Electrochemical Bond Functionalization

Informazioni relative al progetto

ElectroFun

ID dell’accordo di sovvenzione: 101021358

DOI

10.3030/101021358

Data della firma CE 28 Luglio 2021

Data di avvio 1 Agosto 2021

Data di completamento 31 Luglio 2026

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 2 499 423,75

Contributo UE

€ 2 499 423,75

Coordinato da

GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (42)

Direct Synthesis of C4-Acyl Indoles via C–H Acylation

Autori: Bo-Sheng Zhang, Ze-Qiang Zhang, Tian-Jiao Guo, João C. A. Oliveira, Svenja Warratz, Bao-Jie Deng, Yi-Ming Wang, Jun-Shi Zhou, Xue-Ya Gou, Xi-Cun Wang, Zheng-Jun Quan, Lutz Ackermann
Pubblicato in: Organic Letters, Numero 26, 2024, Pagina/e 4998-5003, ISSN 1523-7060
Editore: American Chemical Society
DOI: 10.1021/acs.orglett.4c01658

Close‐Shell Reductive Elimination versus Open‐Shell Radical Coupling for Site‐Selective Ruthenium‐Catalyzed C−H Activations by Computation and Experiments

Autori: Xinran Chen, Hasret Can Gülen, Jun Wu, Zi‐Jing Zhang, Xin Hong, Lutz Ackermann
Pubblicato in: Angewandte Chemie International Edition, Numero 62, 2023, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202302021

Manganese(I)-Catalyzed C–H Allylation of Tryptophans and Their Oligopeptides On Water

Autori: Fabrice Gallou, Lutz Ackermann, Julia Struwe, Tsuyoshi Oyama
Pubblicato in: Synlett, Numero 35, 2024, Pagina/e 903-907, ISSN 0936-5214
Editore: Georg Thieme Verlag
DOI: 10.1055/a-2268-4678

Site-selective electrochemical carboxylation of aromatic C(sp2)–H bonds with CO2

Autori: Rong Zhao, Max Surke, Zhipeng Lin, Ali Alsalme, Lutz Ackermann
Pubblicato in: Current Research in Green and Sustainable Chemistry, Numero 7, 2024, Pagina/e 100377, ISSN 2666-0865
Editore: Elsevier
DOI: 10.1016/j.crgsc.2023.100377

Radical cascade cyclization of 1,<i>n</i>-enynes under photo/electrochemical conditions

Autori: Zhenzhi Cai, Sven Trienes, Kairui Liu, Lutz Ackermann, Yan Zhang
Pubblicato in: Organic Chemistry Frontiers, Numero 10, 2024, Pagina/e 5735-5745, ISSN 2052-4129
Editore: Royal Society of Chemistry
DOI: 10.1039/d3qo01482g

Enantioselective electrochemical cobalt-catalyzed aryl C–H activation reactions

Autori: Tristan von Münchow, Suman Dana, Yang Xu, Binbin Yuan, Lutz Ackermann
Pubblicato in: Science, Numero 379, 2024, Pagina/e 1036-1042, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.adg2866

Metallaelectro-catalyzed alkyne annulations <i>via</i> C–H activations for sustainable heterocycle syntheses

Autori: Preeti Kushwaha, Anjali Saxena, Tristan von Münchow, Suman Dana, Biswajit Saha, Lutz Ackermann
Pubblicato in: Chemical Communications, 2024, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/d4cc03871a

Machine learning-guided yield optimization for palladaelectro-catalyzed annulation reaction

Autori: Xiaoyan Hou, Shuwen Li, Johanna Frey, Xin Hong, Lutz Ackermann
Pubblicato in: Chem, Numero 10, 2024, Pagina/e 2283-2294, ISSN 2451-9294
Editore: Elsevier
DOI: 10.1016/j.chempr.2024.03.027

Combined C-H amination and intermolecular alkyne insertion for a three-component cyclization

Autori: Bo-Sheng Zhang, Yu-Xi Yang, João C.A. Oliveira, Ze-Qiang Zhang, Svenja Warratz, Yi-Ming Wang, Shun-Xi Li, Xi-Cun Wang, Xue-Ya Gou, Yong-Min Liang, Zheng-Jun Quan, Lutz Ackermann
Pubblicato in: Cell Reports Physical Science, Numero 4, 2023, Pagina/e 101647, ISSN 2666-3864
Editore: Elsevier
DOI: 10.1016/j.xcrp.2023.101647

Electrochemical C7‐Indole Alkenylation <i>via</i> Rhodium Catalysis

Autori: Agnese Zangarelli, Binbin Yuan, Lutz Ackermann
Pubblicato in: Israel Journal of Chemistry, Numero 64, 2024, ISSN 0021-2148
Editore: Laser Pages Publishing Ltd.
DOI: 10.1002/ijch.202300103

Template Synthesis to Solve the Unreachable <i>Ortho</i> C–H Functionalization Reaction of Aryl Iodide

Autori: Bo-Sheng Zhang, Wan-Yuan Jia, Yi-Ming Wang, João C. A. Oliveira, Svenja Warratz, Ze-Qiang Zhang, Xue-Ya Gou, Yong-Min Liang, Xi-Cun Wang, Zheng-Jun Quan, Lutz Ackermann
Pubblicato in: The Journal of Organic Chemistry, Numero 88, 2023, Pagina/e 16539-16546, ISSN 0022-3263
Editore: American Chemical Society
DOI: 10.1021/acs.joc.3c02014

Photoinduced C–H arylation of 1,3-azoles <i>via</i> copper/photoredox dual catalysis

Autori: Sven Trienes, Jiawei Xu, Lutz Ackermann
Pubblicato in: Chemical Science, Numero 15, 2024, Pagina/e 7293-7299, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d4sc00393d

Weak-coordination-auxiliary aminocatalysis enables directed [3 + 2] cyclization for 2-acylindolizines

Autori: Kui Zeng, Neeraj Kumar Pandit, João C. A. Oliveira, Sebastian Dechert, Lutz Ackermann, Kai Zhang
Pubblicato in: Green Chemistry, Numero 26, 2024, Pagina/e 5253-5259, ISSN 1463-9262
Editore: Royal Society of Chemistry
DOI: 10.1039/d3gc03552b

Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification

Autori: Zhipeng Lin, Uttam Dhawa, Xiaoyan Hou, Max Surke, Binbin Yuan, Shu-Wen Li, Yan-Cheng Liou, Magnus J. Johansson, Li-Cheng Xu, Chen-Hang Chao, Xin Hong, Lutz Ackermann
Pubblicato in: Nature Communications, Numero 14, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-39747-0

Late-stage synthesis of heterobifunctional molecules for PROTAC applications via ruthenium-catalysed C‒H amidation

Autori: Daniele Antermite, Stig D. Friis, Johan R. Johansson, Okky Dwichandra Putra, Lutz Ackermann, Magnus J. Johansson
Pubblicato in: Nature Communications, Numero 14, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-43789-9

Photoelectrochemical Iron-Catalyzed C(sp ³ )–H Borylation of Alkanes in a Position-Selective Manner

Autori: Wen Wei, Bin Wang, Simon L. Homölle, Jinbin Zhu, Yanjun Li, Tristan von Münchow, Isaac Maksso, Lutz Ackermann
Pubblicato in: CCS Chemistry, Numero 6, 2024, Pagina/e 1430-1438, ISSN 2096-5745
Editore: Chinese Chemical Society
DOI: 10.31635/ccschem.024.202403894

Photoelectrochemical Si–H and Ge–H activation by iron catalysis

Autori: Wen Wei, Simon L. Homölle, Tristan von Münchow, Yanjun Li, Isaac Maksso, Lutz Ackermann
Pubblicato in: Cell Reports Physical Science, Numero 4, 2024, Pagina/e 101550, ISSN 2666-3864
Editore: Elsevier
DOI: 10.1016/j.xcrp.2023.101550

Nickel-Catalyzed Atroposelective C–H Alkylation Enabled by Bimetallic Catalysis with Air-Stable Heteroatom-Substituted Secondary Phosphine Oxide Preligands

Autori: Zi-Jing Zhang, Matthias M. Simon, Shuang Yu, Shu-Wen Li, Xinran Chen, Silvia Cattani, Xin Hong, Lutz Ackermann
Pubblicato in: Journal of the American Chemical Society, Numero 146, 2024, Pagina/e 9172-9180, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.3c14600

Anodic Commodity Polymer Recycling: The Merger of Iron‐Electrocatalysis with Scalable Hydrogen Evolution Reaction

Autori: Maxime Hourtoule, Sven Trienes, Lutz Ackermann
Pubblicato in: Angewandte Chemie International Edition, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202412689

Electrochemical Late-Stage Functionalization

Autori: Yulei Wang, Suman Dana, Hao Long, Yang Xu, Yanjun Li, Nikolaos Kaplaneris, Lutz Ackermann
Pubblicato in: Chemical Reviews, Numero 123, 2023, Pagina/e 11269-11335, ISSN 0009-2665
Editore: American Chemical Society
DOI: 10.1021/acs.chemrev.3c00158

The crucial role of silver(<scp>i</scp>)-salts as additives in C–H activation reactions: overall analysis of their versatility and applicability

Autori: Renato L. de Carvalho, Emilay B. T. Diogo, Simon L. Homölle, Suman Dana, Eufrânio N. da Silva Júnior, Lutz Ackermann
Pubblicato in: Chemical Society Reviews, Numero 52, 2024, Pagina/e 6359-6378, ISSN 0306-0012
Editore: Royal Society of Chemistry
DOI: 10.1039/d3cs00328k

Electrochemical Syntheses of Polycyclic Aromatic Hydrocarbons (PAHs)

Autori: Yulei Wang, Rong Zhao, Lutz Ackermann
Pubblicato in: Advanced Materials, Numero 35, 2024, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202300760

Bifurcated Rhodaelectro-catalyzed C–H Activation for the Synthesis of Pyrroles and Lactones

Autori: Simon L. Homölle, Maximilian Stangier, Efraim Reyes, Lutz Ackermann
Pubblicato in: Precision Chemistry, Numero 1, 2023, Pagina/e 382-387, ISSN 2771-9316
Editore: American Chemical Society
DOI: 10.1021/prechem.3c00061

Polymer up-cycling by mangana-electrocatalytic C(sp³)–H azidation without directing groups

Autori: Isaac Maksso, Ramesh C. Samanta, Yifei Zhan, Kai Zhang, Svenja Warratz, Lutz Ackermann
Pubblicato in: Chemical Science, Numero 14, 2024, Pagina/e 8109-8118, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d3sc02549g

Electrocatalytic Formal C(sp²)−H Alkylations via Nickel‐Catalyzed Cross‐Electrophile Coupling with Versatile Arylsulfonium Salts

Autori: Takuya Michiyuki, Simon L. Homölle, Neeraj K. Pandit, Lutz Ackermann
Pubblicato in: Angewandte Chemie International Edition, Numero 63, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202401198

Electrochemical Rearrangement for Remote Functionalizations of Unactivated Alkenes

Autori: Dingyi Wang, Binbin Yuan, Jiawei Xu, Lutz Ackermann
Pubblicato in: Chemistry – A European Journal, Numero 29, 2024, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202300600

Electrochemical Sulphenylation/Cyclization of Quinones: A Rapid, Green, and Efficient Access to Cytotoxic Compounds

Autori: Emilay B. T. Diogo, Fábio G. Delolo, Gabriela A. P. Graça, Esther R. S. Paz, Ícaro A. O. Bozzi, Renata Diniz, Juliano P. Passos, Tulio Matencio, Liane K. Soares, Diego Alves, Pedro M. S. Costa, Claudia Pessoa, Cynthia L. M. Pereira, Lutz Ackermann, Eufrânio N. da Silva Júnior
Pubblicato in: European Journal of Organic Chemistry, Numero 26, 2023, ISSN 1434-193X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202300506

Cobaltaelectro-Catalyzed C–H Annulation with Allenes for Atropochiral and <i>P</i>-Stereogenic Compounds: Late-Stage Diversification and Continuous Flow Scale-Up

Autori: Ye Lin, Tristan von Münchow, Lutz Ackermann
Pubblicato in: ACS Catalysis, Numero 13, 2023, Pagina/e 9713-9723, ISSN 2155-5435
Editore: American Chemical Society
DOI: 10.1021/acscatal.3c02072

Photoelectrocatalytic [4+2] Annulation for <i>S</i>‐Heterocycle Assembly Enabled by Proton‐Coupled Electron Transfer (PCET)

Autori: Yuan‐Yuan Cheng, Jiawei Xu, Zhipeng Lin, Yanjun Li, Lutz Ackermann
Pubblicato in: Chemistry – A European Journal, 2024, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202402333

Recent advances in organic electrochemical functionalizations for specialty chemicals

Autori: Yanjun Li, Suman Dana, Lutz Ackermann
Pubblicato in: Current Opinion in Electrochemistry, Numero 40, 2024, Pagina/e 101312, ISSN 2451-9103
Editore: Elsevier
DOI: 10.1016/j.coelec.2023.101312

Photo‐Induced Ruthenium‐Catalyzed C−H Arylation Polymerization at Ambient Temperature

Autori: Takuya Michiyuki, Isaac Maksso, Lutz Ackermann
Pubblicato in: Angewandte Chemie International Edition, Numero 63, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202400845

Room temperature photo-promoted iron-catalysed arene C–H alkenylation without Grignard reagents

Autori: Antonis M. Messinis, Tristan von Münchow, Max Surke, Lutz Ackermann
Pubblicato in: Nature Catalysis, Numero 7, 2024, Pagina/e 273-284, ISSN 2520-1158
Editore: Springer Nature
DOI: 10.1038/s41929-023-01105-0

Electrochemical assembly of isoxazoles <i>via</i> a four-component domino reaction

Autori: Yuanyuan Zhao, Xinyue Li, Simon L. Homölle, Bin Wang, Lutz Ackermann
Pubblicato in: Chemical Science, Numero 15, 2024, Pagina/e 1117-1122, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d3sc05946d

Cobaltaelectro‐Catalyzed C–H Activation for Central and Axial Double Enantio‐Induction

Autori: Tristan von Münchow, Yi‐Ru Liu, Rahul Parmar, Sven Erik Peters, Sven Trienes, Lutz Ackermann
Pubblicato in: Angewandte Chemie International Edition, Numero 63, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202405423

Electrochemical Glycosylation via Halogen-Atom-Transfer for <i>C</i>-Glycoside Assembly

Autori: Jun Wu, Rajeshwaran Purushothaman, Felix Kallert, Simon L. Homölle, Lutz Ackermann
Pubblicato in: ACS Catalysis, Numero 14, 2024, Pagina/e 11532-11544, ISSN 2155-5435
Editore: American Chemical Society
DOI: 10.1021/acscatal.4c02322

Electrochemical Skeletal Indole Editing via Nitrogen Atom Insertion by Sustainable Oxygen Reduction Reaction

Autori: Bo‐Sheng Zhang, Simon L. Homölle, Tristan Bauch, João C. A. Oliveira, Svenja Warratz, Binbin Yuan, Xue‐Ya Gou, Lutz Ackermann
Pubblicato in: Angewandte Chemie International Edition, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202407384

Chelation-Assisted Iron-Catalyzed C–H Activations: Scope and Mechanism

Autori: Jiayu Mo, Antonis M. Messinis, Jinlian Li, Svenja Warratz, Lutz Ackermann
Pubblicato in: Accounts of Chemical Research, Numero 57, 2024, Pagina/e 10-22, ISSN 0001-4842
Editore: American Chemical Society
DOI: 10.1021/acs.accounts.3c00294

Enantioselective Cobaltaphotoredox-Catalyzed C–H Activation

Autori: Yang Xu, Ye Lin, Simon L. Homölle, João C. A. Oliveira, Lutz Ackermann
Pubblicato in: Journal of the American Chemical Society, Numero 146, 2024, Pagina/e 24105-24113, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.4c08459

Data-driven design of new chiral carboxylic acid for construction of indoles with C-central and C–N axial chirality via cobalt catalysis

Autori: Zi-Jing Zhang, Shu-Wen Li, João C. A. Oliveira, Yanjun Li, Xinran Chen, Shuo-Qing Zhang, Li-Cheng Xu, Torben Rogge, Xin Hong, Lutz Ackermann
Pubblicato in: Nature Communications, Numero 14, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-38872-0

Electrochemical Enantioselective C–H Annulation by Achiral Rhodium(III)/Chiral Brønsted Base Domino Catalysis

Autori: Yanjun Li, Jiawei Xu, João C. A. Oliveira, Alexej Scheremetjew, Lutz Ackermann
Pubblicato in: ACS Catalysis, Numero 14, 2024, Pagina/e 8160-8167, ISSN 2155-5435
Editore: American Chemical Society
DOI: 10.1021/acscatal.4c01886

Well‐Defined Highly‐Coordinated Copper(III) Iodide and Pincer Tris(trifluoromethyl)copper Complexes

Autori: Vladimir Motornov, Lutz Ackermann
Pubblicato in: Chemistry – A European Journal, 2024, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202401791

Palladium-Catalyzed Electrooxidative Double C–H Arylation

Autori: Zhipeng Lin, João C. A. Oliveira, Alexej Scheremetjew, Lutz Ackermann
Pubblicato in: Journal of the American Chemical Society, Numero 146, 2024, Pagina/e 228-239, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.3c08479