Project description
A sustainable way of producing novel antibiotics
Polyketides are a large class of secondary metabolites from bacteria, fungi and plants with interesting and valuable activities. They are exploited as antibiotics, antifungals and drugs and can be chemically synthesised or produced from biological sources. The EU-funded PrediKSion project proposes to exploit acyltransferase polyketide synthase (AT PKS) enzymes from bacteria as a sustainable way to produce polyketides. To unveil new biosynthetic features in AT PKS, researchers will develop a computational pipeline that will assess the functionality of uncharacterised enzymes. Long term this will lead to the discovery of novel pharmaceutical entities
Fields of science
Programme(s)
Funding Scheme
MSCA-IF-EF-ST - Standard EFCoordinator
8092 Zuerich
Switzerland
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