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Semi-Autonomous ProtoTissues capable of photo-Mechano-Chemical transduction

Project description

Soft materials based on synthetic prototissues

Protocells, artificial cell-like entities, are a vital tool in synthetic biology. These non-living systems demonstrate characteristics akin to biological cells. Protocell networks in prototissues can communicate and display synergistic functions, yet lack robustness and the required complexity to perform higher-order functions. Funded by the Marie Skłodowska-Curie Actions programme, the SAPTiMeC project will exploit spiropyran photoswitches to fabricate prototissues that can swell and de-swell powered by light. This mechanical movement will then be exploited to modulate the prototissue’s endogenous photocatalytic reactivity, producing waves of an output chemical signal. Project outcomes could usher in a new era in bottom-up synthetic biology and non-equilibrium systems, delivering new materials with potential use in tissue engineering and soft robotics.

Coordinator

UNIVERSITA DEGLI STUDI DI TRIESTE
Net EU contribution
€ 150 039,12
Address
Piazzale Europa 1
34127 Trieste
Italy

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Region
Nord-Est Friuli-Venezia Giulia Trieste
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (1)

UNIVERSITY OF BRISTOL

Participation ended

United Kingdom
Net EU contribution
€ 26 616,72
Address
Beacon House Queens Road
BS8 1QU Bristol
Region
South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Bristol, City of
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00