Project description
A non-invasive way to measure dopamine
Dopamine is a prescription medicine used to treat symptoms of low blood pressure and to improve blood flow to the kidneys. Dopamine agonists are also used to treat Parkinson’s disease and restless legs syndrome which is a common problem for people with Parkinson’s. In this context, the EU-funded BEACON project will develop a wearable patch for continuous dopamine sensing. Specifically, it will use biocompatible materials and additive manufacturing techniques that would enable around-the-clock monitoring of this hormone. This non-invasive device, which analyses dopamine concentration in human sweat, will be self-powered using the patient’s body heat as a source of energy.
Objective
The following proposal deals with the fabrication and validation of a wearable patch for continuous dopamine sensing, realized using biocompatible materials and additive manufacturing techniques, which would allow to monitor the evolution throughout the day of this hormone which is fundamental in the treatment of many neurological diseases. The candidate wants to provide a simple and non-invasive method which could potentially improve the quality of life of millions of patients and families affected by these diseases and reduce the growing social costs to treat them. The device is thought to be self-powered, using the patients’ body heat as energy source, and works by analysing the dopamine concentration in human sweat, therefore no surgical procedure is required. To detect dopamine concentration, organic electrochemical transistors are used, exploiting their amplification ability to obtain a highly sensitive monitoring device. The patch is also equipped with a radio-frequency antenna for data transmission to medical personnel monitoring real-time the dopamine evolution in the patients. Finally, the patch is designed to be conformable, lightweight and cheap to reduce the patients’ discomfort.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine surgery surgical procedures
- engineering and technology mechanical engineering manufacturing engineering additive manufacturing
- engineering and technology medical engineering wearable medical technology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
581 83 Linkoping
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.