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Cellular and Biophysical Approach to Understand the Cytokine-mediated Regulation of the Lysosomal Hydrolytic Capacity

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein (opens in new window)

Author(s): Silvia Gaggero , Jonathan Martinez-Fabregas, Adeline Cozzani, Paul K Fyfe, Malo Leprohon , Jie Yang, F Emil Thomasen, Hauke Winkelmann, Romain Magnez, Alberto G Conti, Stephan Wilmes, Elizabeth Pohler, Manuel van Gijsel Bonnello, Xavier Thuru, Bruno Quesnel, Fabrice Soncin, Jacob Piehler, Kresten Lindorff-Larsen, Rahul Roychoudhuri, Ignacio Moraga, Suman Mitra
Published in: Science Immunology, 2022, ISSN 2470-9468
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.ade5686

Lysosomes: multifunctional compartments ruled by a complex regulatory network (opens in new window)

Author(s): Jonathan Martinez Fabregas Joaquin Tamargo Azpilicueta Irene Diaz Moreno
Published in: FEBS Open Bio, 2022, ISSN 2211-5463
Publisher: Elsevier BV
DOI: 10.1002/2211-5463.13387

Nucleus-translocated mitochondrial cytochrome c liberates nucleophosmin-sequestered ARF tumor suppressor by changing nucleolar liquid–liquid phase separation (opens in new window)

Author(s): Katiuska González-Arzola Antonio Díaz-Quintana Noelia Bernardo-García Jonathan Martínez-Fábregas Francisco Rivero-Rodríguez Miguel Á. Casado-Combreras Carlos A. Elena-Real Alejandro Velázquez-Cruz Sergio Gil-Caballero Adrián Velázquez-Campoy Elzbieta Szulc María P. Gavilán Isabel Ayala Rocío Arranz Rosa M. Ríos Xavier Salvatella José M. Valpuesta Juan A. Hermoso Miguel A. De la Rosa
Published in: Nature Structural and Molecular Biology, 2022, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-022-00842-3

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