Project description
Pathways for lysosome regulation
Lysosomes, cell organelles containing hydrolytic enzymes, participate in key physiological processes of cells. Lysosome dysfunction is known to be involved at the onset of an ample set of human diseases. Importantly, most of the functions carried out by lysosomes depend on hydrolytic activities within their lumen. Nonetheless, the regulation of lysosome activities and their role in cell fate governance still raise crucial questions. Therefore, a deeper understanding of the signalling pathways governing the regulation of lysosomes could provide new therapeutic tools to treat these diseases. The EU-funded CytoLysoReg project will investigate the molecular and biophysical properties that enable cytokines to regulate lysosomes. The goal is to allow scientists to manipulate lysosomes as an approach to treat lysosomal-related diseases.
Fields of science
- engineering and technologyenvironmental engineeringwaste managementwaste treatment processesrecycling
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
- medical and health sciencesclinical medicineoncology
- medical and health sciencesbasic medicinephysiology
- natural sciencesbiological sciencesbiophysics
Programme(s)
Call for proposal
H2020-MSCA-IF-2020
See other projects for this call
Funding Scheme
MSCA-IF-EF-ST - Standard EFCoordinator
41004 Sevilla
Spain
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