The impact of hyperammonemia in viral infection pathophysiology

Project description

Ammonia in anti-viral immune response

Besides being a neurotoxic waste product, ammonia is also involved in energy production as well as cell proliferation and survival. Being a gaseous molecule, it can travel within the body and influence immune responses and tissue homeostasis. The scope of the EU-funded AmmoniaVir project is to understand how elevated ammonia levels are associated with viral infection. Researchers will employ a multidisciplinary approach to study the role of virus-induced liver damage on elevated ammonia levels and how this metabolite affects other tissues including the brain. The project's results will not only unveil novel aspects of host immune responses against viruses but also provide important knowledge on metabolic disorders.

Fields of science

• medical and health sciences › basic medicine › immunology

Programme(s)

• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2020 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2020
See other projects for this call

Funding Scheme

MSCA-IF-EF-SE - Society and Enterprise panel

Coordinator

CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH

Address

Lazarettgasse 14 Akh Bt 25.3
1090 Wien
Austria

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

EU contribution

€ 174 167,04