Descripción del proyecto
Catalizadores de oro podrían ayudar a la síntesis de polímeros de acetileno
El proyecto GASGOLD, financiado por las Acciones Marie Skłodowska-Curie, estudiará el uso de complejos de oro ―Au(I)― como catalizadores para las síntesis de importantes monómeros, oligómeros y polímeros del acetileno. Los complejos de Au(I) han demostrado ser catalizadores adecuados para la formación de ciclopropilcarbenos de Au(I) tras reaccionar con un alquino o alqueno. En particular, el proyecto investigará la reacción de determinados 1,3-dienos con acetileno, lo cual da lugar a la formación de derivados oligoméricos. Los resultados resolverán el problema de utilizar gas acetileno como componente básico simple en la catálisis del Au(I).
Objetivo
GASGOLD aims for the development of efficient Au(I)-catalysed methodologies for the challenging intermolecular synthesis of important monomers, oligomers and polymers of acetylene gas. Au(I)-catalysts allow for the formation of cyclopropyl Au(I)-carbenes after reaction with an alkyne and alkene. The carbenes are reactive towards rearrangement to form 1,3-dienes, which are important building blocks for a range of natural and other important products, such as synthetic rubbers. Preliminary results show that further reaction of certain 1,3-dienes with acetylene can occur, forming oligomeric derivatives and this reactivity will be harnessed and further exploited in this project. Initially, the development of an effective protocol for the synthesis of a wider range and more challenging substituted 1,3-dienes from acetylene gas, both in monomeric and oligomeric forms, will be established. The reaction mechanism determining the configuration of the alkenes will be studied, for example by kinetic monitoring and isolation of reaction intermediates, to explain the observed selectivity, potentially synthesise other isomers and improve on the reaction conditions and catalyst design. The initial results will inspire the challenging selective expansion of 1,3-dienes with acetylene to form substituted 1,3,5-hexatrienes. Additionally, the unprecedented use of both acetylene and ethylene gas in Au(I)-catalysis will be explored for the synthesis of polyacetylene derivatives, which are highly important materials with electrical conductivity, as well as in the purification of ethylene gas. The development of this project offers an innovative solution for the long-standing problem of utilising acetylene gas as a simple building block in Au(I)-catalysis, offering a clear advantage over the current state-of-the-art of the field. Furthermore, the expected synergistic performance between the experienced researcher and the host group, will maximise the potential for success of the project.
Ámbito científico
Programa(s)
Régimen de financiación
MSCA-IF-EF-ST - Standard EFCoordinador
43007 Tarragona
España