Eucor Upper Rhine Immunology doctoral programme

Project Information

EURIdoc

Grant agreement ID: 101034170

DOI

10.3030/101034170

EC signature date 30 April 2021

Start date 1 September 2021

End date 31 May 2027

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 6 074 880,00

EU contribution

€ 3 037 440,00

Coordinated by

EUCOR - THE EUROPEAN CAMPUS
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (20)

Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation

Author(s): Benedikt S. Saller, Svenja Wöhrle, Larissa Fischer, Clara Dufossez, Isabella L. Ingerl, Susanne Kessler, Maria Mateo-Tortola, Oliver Gorka, Felix Lange, Yurong Cheng, Emilia Neuwirt, Adinarayana Marada, Christoph Koentges, Chiara Urban, Philipp Aktories, Peter Reuther, Sebastian Giese, Susanne Kirschnek, Carolin Mayer, Johannes Pilic, Hugo Falquez-Medina, Aline Oelgeklaus, Veerasikku Gopal Deepag
Published in: Immunity, Issue 58, 2025, Page(s) 90-107.e11, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2024.10.012

Chemoproteomik‐basierte Identifikation von 4‐Oxo‐β‐lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9

Author(s): Luís A. R. Carvalho, Breyan Ross, Lorenz Fehr, Oguz Bolgi, Svenja Wöhrle, Kenneth M. Lum, David Podlesainski, Andreia C. Vieira, Reiner Kiefersauer, Rita Félix, Tiago Rodrigues, Susana D. Lucas, Olaf Groß, Ruth Geiss‐Friedlander, Benjamin F. Cravatt, Robert Huber, Markus Kaiser, Rui Moreira
Published in: Angewandte Chemie, Issue 134, 2023, ISSN 0044-8249
Publisher: Wiley
DOI: 10.1002/ange.202210498

Granulocytes and mast cells in AllergoOncology—Bridging allergy to cancer: An <scp>EAACI</scp> position paper

Author(s): Mariona Pascal, Heather J. Bax, Christoph Bergmann, Rodolfo Bianchini, Mariana Castells, Jitesh Chauhan, Leticia De las Vecillas, Karin Hartmann, Elena Izquierdo Álvarez, Uta Jappe, Teodorikez‐Wilfox Jimenez‐Rodriguez, Edward Knol, Francesca Levi‐Schaffer, Cristobalina Mayorga, Aurélie Poli, Frank Redegeld, Alexandra F. Santos, Erika Jensen‐Jarolim, Sophia N. Karagiannis
Published in: Allergy, Issue 79, 2025, Page(s) 2319-2345, ISSN 0105-4538
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/all.16246

Fecal Immunoglobulin Levels as a Modifier of the Gut Microbiome in Patients with Common Variable Immunodeficiency

Author(s): Christina Nöltner, Alla Bulashevska, Katrin Hübscher, Hanna Haberstroh, Bodo Grimbacher, Michele Proietti
Published in: Journal of Clinical Immunology, Issue 43, 2023, Page(s) 1208-1220, ISSN 0271-9142
Publisher: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10875-023-01469-9

A novel transmembrane <i>CXCR4</i> variant that expands the WHIM genotype-phenotype paradigm

Author(s): Katarina Zmajkovicova, Sumit Pawar, Svetlana O. Sharapova, Christoph B. Geier, Ivana Wiest, Chi Nguyen, Halenya Monticelli, Sabine Maier-Munsa, Kelly Chen, John W. Sleasman, Svetlana Aleshkevich, Ekaterina Polyakova, Inga Sakovich, Klaus Warnatz, Bodo Grimbacher, Michele Proietti, Neal Sondheimer, Boglarka Ujhazi, Sumai Gordon, Maryssa Ellison, Melis Yilmaz, Jolan E. Walter, Adriana Badarau, Arthu
Published in: Blood Advances, Issue 8, 2024, Page(s) 3754-3759, ISSN 2473-9529
Publisher: American Society of Hematology
DOI: 10.1182/bloodadvances.2023011875

mRNA prime-boost vaccination promotes clonal continuity in germinal center reactions and broadens SARS-CoV-2 variant coverage

Author(s): Matias Ciancaglini, Jonas Fixemer, Cemre Seven, Mirela Dimitrova, Davide Finozzi, Denice Weklak, Anna Lena Kastner, Franziska Jönsson, Ingrid Wagner, Ilena Vincenti, Anneli Peters, Maddy L. Newby, Max Crispin, Doron Merkler, Florian Kreppel, Daniel D. Pinschewer
Published in: Molecular Therapy, 2025, ISSN 1525-0016
Publisher: Nature Publishing Group
DOI: 10.1016/j.ymthe.2025.08.008

Age- and Elicitor-Dependent Characterization of Hymenoptera Venom-Induced Anaphylaxis in Children and Adolescents

Author(s): Margitta Worm, Ewa Cichocka-Jarosz, Franziska Ruëff, Thomas Spindler, Alice Köhli, Johannes Trück, Lars Lange, Karin Hartmann, Thomas Hawranek, Katja Nemat, Claudia Pföhler, Maria Beatrice Bilò, Dominique Sabouraud-Leclerc, Nicola Wagner, Nikolaos Papadopoulos, Susanne Hämmerling, Luis Felipe Ensina, Sabine Dölle-Bierke, Veronika Höfer
Published in: The Journal of Allergy and Clinical Immunology: In Practice, Issue 13, 2025, Page(s) 69-78.e2, ISSN 2213-2198
Publisher: Elsevier
DOI: 10.1016/j.jaip.2024.08.036

Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity

Author(s): Dominik Soll, Chang-Feng Chu, Shan Sun, Veronika Lutz, Mahima Arunkumar, Mariam Gachechiladze, Sascha Schäuble, Maha Alissa-Alkhalaf, Trang Nguyen, Michelle-Amirah Khalil, Ignacio Garcia-Ribelles, Michael Mueller, Katrin Buder, Bernhard Michalke, Gianni Panagiotou, Kai Ziegler-Martin, Pascal Benz, Philipp Schatzlmaier, Karsten Hiller, Hannes Stockinger, Maik Luu, Kilian Schober, Carolin Moosmann,
Published in: Nature Immunology, Issue 25, 2024, Page(s) 1830-1844, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-024-01918-6

Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9

Author(s): Luís A. R. Carvalho, Breyan Ross, Lorenz Fehr, Oguz Bolgi, Svenja Wöhrle, Kenneth M. Lum, David Podlesainski, Andreia C. Vieira, Reiner Kiefersauer, Rita Félix, Tiago Rodrigues, Susana D. Lucas, Olaf Groß, Ruth Geiss‐Friedlander, Benjamin F. Cravatt, Robert Huber, Markus Kaiser, Rui Moreira
Published in: Angewandte Chemie International Edition, Issue 61, 2023, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202210498

β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner

Author(s): Verena B. Eisenbeis, Danye Qiu, Oliver Gorka, Lisa Strotmann, Guizhen Liu, Isabel Prucker, Xue Bessie Su, Miranda S. C. Wilson, Kevin Ritter, Christoph Loenarz, Olaf Groß, Adolfo Saiardi, Henning J. Jessen
Published in: Proceedings of the National Academy of Sciences, Issue 120, 2023, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2306868120

Size exclusion chromatography based proteomic and degradomic profiling of inflammasome-activated, murine bone marrow-derived dendritic cells highlights complex retention and release of cleavage products

Author(s): Daniel Vogele, Svenja Wöhrle, Benedikt S. Saller, Klemens Fröhlich, Bálint András Barta, Miguel Cosenza-Contreras, Olaf Groß, Oliver Schilling
Published in: Molecular Omics, Issue 20, 2024, Page(s) 595-610, ISSN 2515-4184
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/d4mo00163j

Anti-HLA Class I alloantibodies in platelet transfusion refractoriness: From mechanisms and determinants to therapeutic prospects

Author(s): Couvidou A, Rojas-Jiménez G, Dupuis A and Maître B
Published in: Frontiers in Immunology, 2023, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2023.1125367

Lymphoid stromal cells - potential implications for the pathogenesis of CVID

Author(s): Cousin VN, Perez GF, Payne KJ, Voll RE, Rizzi M, Mueller CG and Warnatz K
Published in: Frontiers in Immunology, 2023, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2023.1122905

T-cell–B-cell collaboration in the lung

Author(s): Naderi W, Schreiner D, and King CG
Published in: Current Opinion in Immunology, 2023, ISSN 0952-7915
Publisher: Elsevier BV
DOI: 10.1016/j.coi.2023.102284

ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality

Author(s): Elena Sindram, Andrés Caballero-Oteyza, Naoko Kogata, Shaina Chor Mei Huang, Zahra Alizadeh, Laura Gámez-Díaz, Mohammad Reza Fazlollhi, Xiao Peng, Bodo Grimbacher, Michael Way, Michele Proietti
Published in: Disease Models &amp; Mechanisms, Issue 16, 2023, ISSN 1754-8403
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dmm.050145

Sabotaging TCR signaling—LAG3 interferes with the CD3ε–LCK interaction

Author(s): Gina J. Fiala, Wolfgang W. Schamel
Published in: Cell Research, 2025, ISSN 1748-7838
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41422-025-01168-7

Post-transplant Inflammatory Bowel Disease Associated with Donor-Derived TIM-3 Deficiency

Author(s): Baldrich, Adrian; Althaus, Dominic; Menter, Thomas; Hirsiger, Julia R.; Köppen, Julius; Hupfer, Robin; Juskevicius, Darius; Konantz, Martina; Bosch, Angela; Drexler, Beatrice; Gerull, Sabine; Ghosh, Adhideb; id_orcid0000-0002-5160-4571; Meyer, Benedikt J.; Jauch, Annaise; Pini, Katia; Poletti, Fabio; Berkemeier, Caroline M.; Heijnen, Ingmar; Panne, Isabelle; Cavelti-Weder, Claudia; et al.
Published in: Journal of Clinical Immunology, 44 (3), Issue 1, 2024, ISSN 1573-2592
Publisher: Springer Nature
DOI: 10.3929/ethz-b-000661697

A Growing Concern for Cashew and an Unexpected Risk From Almonds: Data From the Anaphylaxis Registry

Author(s): Veronika Höfer, Sabine Dölle‐Bierke, Dominique Sabouraud‐Leclerc, Amandine Divaret‐Chauveau, Alice Köhli, Maria Breiding, Karin Hartmann, Lars Lange, Nikolaos Papadopoulos, Hagen Ott, Stephanie Hompes, Maria Beatrice Bilò, Blanca E. García, Margitta Worm
Published in: Allergy, Issue 80, 2025, Page(s) 2837-2848, ISSN 0105-4538
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/all.16619

Allele-Specific Disruption of a Common STAT3 Autosomal Dominant Allele Is Not Sufficient to Restore Downstream Signaling in Patient-Derived T Cells

Author(s): Saskia König, Manfred Fliegauf, Manuel Rhiel, Bodo Grimbacher, Tatjana I. Cornu, Toni Cathomen, Claudio Mussolino
Published in: Genes, Issue 13, 2025, Page(s) 1912, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes13101912

Molecular mechanisms underlying NLRP3 inflammasome activation and IL-1β production in air pollution fine particulate matter (PM2.5)-primed macrophages

Author(s): Lourdes Caceres, Tijani Abogunloko, Sara Malchow, Fabienne Ehret, Julian Merz, Xiaowei Li, Lucia Sol Mitre, Natalia Magnani, Deborah Tasat, Timothy Mwinyella, Lisa Spiga, Dymphie Suchanek, Larissa Fischer, Oliver Gorka, Mark Colin Gissler, Ingo Hilgendorf, Peter Stachon, Eva Rog-Zielinska, Olaf Groß, Dirk Westermann, Pablo Evelson, Dennis Wolf, Timoteo Marchini
Published in: Environmental Pollution, Issue 341, 2025, Page(s) 122997, ISSN 0269-7491
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2023.122997

Other (1)

DNA damage signaling in<i>Drosophila</i>macrophages modulates systemic cytokine levels in response to oxidative stress

Author(s): Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S. Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf
Published in: 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.02.22.529599