Eucor Upper Rhine Immunology doctoral programme

Informazioni relative al progetto

EURIdoc

ID dell’accordo di sovvenzione: 101034170

DOI

10.3030/101034170

Data della firma CE 30 Aprile 2021

Data di avvio 1 Settembre 2021

Data di completamento 31 Maggio 2027

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 6 074 880,00

Contributo UE

€ 3 037 440,00

Coordinato da

EUCOR - THE EUROPEAN CAMPUS
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (20)

Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation

Autori: Benedikt S. Saller, Svenja Wöhrle, Larissa Fischer, Clara Dufossez, Isabella L. Ingerl, Susanne Kessler, Maria Mateo-Tortola, Oliver Gorka, Felix Lange, Yurong Cheng, Emilia Neuwirt, Adinarayana Marada, Christoph Koentges, Chiara Urban, Philipp Aktories, Peter Reuther, Sebastian Giese, Susanne Kirschnek, Carolin Mayer, Johannes Pilic, Hugo Falquez-Medina, Aline Oelgeklaus, Veerasikku Gopal Deepag
Pubblicato in: Immunity, Numero 58, 2025, Pagina/e 90-107.e11, ISSN 1074-7613
Editore: Cell Press
DOI: 10.1016/j.immuni.2024.10.012

Chemoproteomik‐basierte Identifikation von 4‐Oxo‐β‐lactamen als Inhibitoren der Dipeptidylpeptidasen 8 und 9

Autori: Luís A. R. Carvalho, Breyan Ross, Lorenz Fehr, Oguz Bolgi, Svenja Wöhrle, Kenneth M. Lum, David Podlesainski, Andreia C. Vieira, Reiner Kiefersauer, Rita Félix, Tiago Rodrigues, Susana D. Lucas, Olaf Groß, Ruth Geiss‐Friedlander, Benjamin F. Cravatt, Robert Huber, Markus Kaiser, Rui Moreira
Pubblicato in: Angewandte Chemie, Numero 134, 2023, ISSN 0044-8249
Editore: Wiley
DOI: 10.1002/ange.202210498

Granulocytes and mast cells in AllergoOncology—Bridging allergy to cancer: An <scp>EAACI</scp> position paper

Autori: Mariona Pascal, Heather J. Bax, Christoph Bergmann, Rodolfo Bianchini, Mariana Castells, Jitesh Chauhan, Leticia De las Vecillas, Karin Hartmann, Elena Izquierdo Álvarez, Uta Jappe, Teodorikez‐Wilfox Jimenez‐Rodriguez, Edward Knol, Francesca Levi‐Schaffer, Cristobalina Mayorga, Aurélie Poli, Frank Redegeld, Alexandra F. Santos, Erika Jensen‐Jarolim, Sophia N. Karagiannis
Pubblicato in: Allergy, Numero 79, 2025, Pagina/e 2319-2345, ISSN 0105-4538
Editore: Blackwell Publishing Inc.
DOI: 10.1111/all.16246

Fecal Immunoglobulin Levels as a Modifier of the Gut Microbiome in Patients with Common Variable Immunodeficiency

Autori: Christina Nöltner, Alla Bulashevska, Katrin Hübscher, Hanna Haberstroh, Bodo Grimbacher, Michele Proietti
Pubblicato in: Journal of Clinical Immunology, Numero 43, 2023, Pagina/e 1208-1220, ISSN 0271-9142
Editore: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10875-023-01469-9

A novel transmembrane <i>CXCR4</i> variant that expands the WHIM genotype-phenotype paradigm

Autori: Katarina Zmajkovicova, Sumit Pawar, Svetlana O. Sharapova, Christoph B. Geier, Ivana Wiest, Chi Nguyen, Halenya Monticelli, Sabine Maier-Munsa, Kelly Chen, John W. Sleasman, Svetlana Aleshkevich, Ekaterina Polyakova, Inga Sakovich, Klaus Warnatz, Bodo Grimbacher, Michele Proietti, Neal Sondheimer, Boglarka Ujhazi, Sumai Gordon, Maryssa Ellison, Melis Yilmaz, Jolan E. Walter, Adriana Badarau, Arthu
Pubblicato in: Blood Advances, Numero 8, 2024, Pagina/e 3754-3759, ISSN 2473-9529
Editore: American Society of Hematology
DOI: 10.1182/bloodadvances.2023011875

mRNA prime-boost vaccination promotes clonal continuity in germinal center reactions and broadens SARS-CoV-2 variant coverage

Autori: Matias Ciancaglini, Jonas Fixemer, Cemre Seven, Mirela Dimitrova, Davide Finozzi, Denice Weklak, Anna Lena Kastner, Franziska Jönsson, Ingrid Wagner, Ilena Vincenti, Anneli Peters, Maddy L. Newby, Max Crispin, Doron Merkler, Florian Kreppel, Daniel D. Pinschewer
Pubblicato in: Molecular Therapy, 2025, ISSN 1525-0016
Editore: Nature Publishing Group
DOI: 10.1016/j.ymthe.2025.08.008

Age- and Elicitor-Dependent Characterization of Hymenoptera Venom-Induced Anaphylaxis in Children and Adolescents

Autori: Margitta Worm, Ewa Cichocka-Jarosz, Franziska Ruëff, Thomas Spindler, Alice Köhli, Johannes Trück, Lars Lange, Karin Hartmann, Thomas Hawranek, Katja Nemat, Claudia Pföhler, Maria Beatrice Bilò, Dominique Sabouraud-Leclerc, Nicola Wagner, Nikolaos Papadopoulos, Susanne Hämmerling, Luis Felipe Ensina, Sabine Dölle-Bierke, Veronika Höfer
Pubblicato in: The Journal of Allergy and Clinical Immunology: In Practice, Numero 13, 2025, Pagina/e 69-78.e2, ISSN 2213-2198
Editore: Elsevier
DOI: 10.1016/j.jaip.2024.08.036

Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity

Autori: Dominik Soll, Chang-Feng Chu, Shan Sun, Veronika Lutz, Mahima Arunkumar, Mariam Gachechiladze, Sascha Schäuble, Maha Alissa-Alkhalaf, Trang Nguyen, Michelle-Amirah Khalil, Ignacio Garcia-Ribelles, Michael Mueller, Katrin Buder, Bernhard Michalke, Gianni Panagiotou, Kai Ziegler-Martin, Pascal Benz, Philipp Schatzlmaier, Karsten Hiller, Hannes Stockinger, Maik Luu, Kilian Schober, Carolin Moosmann,
Pubblicato in: Nature Immunology, Numero 25, 2024, Pagina/e 1830-1844, ISSN 1529-2908
Editore: Nature Publishing Group
DOI: 10.1038/s41590-024-01918-6

Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9

Autori: Luís A. R. Carvalho, Breyan Ross, Lorenz Fehr, Oguz Bolgi, Svenja Wöhrle, Kenneth M. Lum, David Podlesainski, Andreia C. Vieira, Reiner Kiefersauer, Rita Félix, Tiago Rodrigues, Susana D. Lucas, Olaf Groß, Ruth Geiss‐Friedlander, Benjamin F. Cravatt, Robert Huber, Markus Kaiser, Rui Moreira
Pubblicato in: Angewandte Chemie International Edition, Numero 61, 2023, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202210498

β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner

Autori: Verena B. Eisenbeis, Danye Qiu, Oliver Gorka, Lisa Strotmann, Guizhen Liu, Isabel Prucker, Xue Bessie Su, Miranda S. C. Wilson, Kevin Ritter, Christoph Loenarz, Olaf Groß, Adolfo Saiardi, Henning J. Jessen
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 120, 2023, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2306868120

Size exclusion chromatography based proteomic and degradomic profiling of inflammasome-activated, murine bone marrow-derived dendritic cells highlights complex retention and release of cleavage products

Autori: Daniel Vogele, Svenja Wöhrle, Benedikt S. Saller, Klemens Fröhlich, Bálint András Barta, Miguel Cosenza-Contreras, Olaf Groß, Oliver Schilling
Pubblicato in: Molecular Omics, Numero 20, 2024, Pagina/e 595-610, ISSN 2515-4184
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/d4mo00163j

Anti-HLA Class I alloantibodies in platelet transfusion refractoriness: From mechanisms and determinants to therapeutic prospects

Autori: Couvidou A, Rojas-Jiménez G, Dupuis A and Maître B
Pubblicato in: Frontiers in Immunology, 2023, ISSN 1664-3224
Editore: Frontiers
DOI: 10.3389/fimmu.2023.1125367

Lymphoid stromal cells - potential implications for the pathogenesis of CVID

Autori: Cousin VN, Perez GF, Payne KJ, Voll RE, Rizzi M, Mueller CG and Warnatz K
Pubblicato in: Frontiers in Immunology, 2023, ISSN 1664-3224
Editore: Frontiers
DOI: 10.3389/fimmu.2023.1122905

T-cell–B-cell collaboration in the lung

Autori: Naderi W, Schreiner D, and King CG
Pubblicato in: Current Opinion in Immunology, 2023, ISSN 0952-7915
Editore: Elsevier BV
DOI: 10.1016/j.coi.2023.102284

ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality

Autori: Elena Sindram, Andrés Caballero-Oteyza, Naoko Kogata, Shaina Chor Mei Huang, Zahra Alizadeh, Laura Gámez-Díaz, Mohammad Reza Fazlollhi, Xiao Peng, Bodo Grimbacher, Michael Way, Michele Proietti
Pubblicato in: Disease Models &amp; Mechanisms, Numero 16, 2023, ISSN 1754-8403
Editore: The Company of Biologists Ltd.
DOI: 10.1242/dmm.050145

Sabotaging TCR signaling—LAG3 interferes with the CD3ε–LCK interaction

Autori: Gina J. Fiala, Wolfgang W. Schamel
Pubblicato in: Cell Research, 2025, ISSN 1748-7838
Editore: Springer Science and Business Media LLC
DOI: 10.1038/s41422-025-01168-7

Post-transplant Inflammatory Bowel Disease Associated with Donor-Derived TIM-3 Deficiency

Autori: Baldrich, Adrian; Althaus, Dominic; Menter, Thomas; Hirsiger, Julia R.; Köppen, Julius; Hupfer, Robin; Juskevicius, Darius; Konantz, Martina; Bosch, Angela; Drexler, Beatrice; Gerull, Sabine; Ghosh, Adhideb; id_orcid0000-0002-5160-4571; Meyer, Benedikt J.; Jauch, Annaise; Pini, Katia; Poletti, Fabio; Berkemeier, Caroline M.; Heijnen, Ingmar; Panne, Isabelle; Cavelti-Weder, Claudia; et al.
Pubblicato in: Journal of Clinical Immunology, 44 (3), Numero 1, 2024, ISSN 1573-2592
Editore: Springer Nature
DOI: 10.3929/ethz-b-000661697

A Growing Concern for Cashew and an Unexpected Risk From Almonds: Data From the Anaphylaxis Registry

Autori: Veronika Höfer, Sabine Dölle‐Bierke, Dominique Sabouraud‐Leclerc, Amandine Divaret‐Chauveau, Alice Köhli, Maria Breiding, Karin Hartmann, Lars Lange, Nikolaos Papadopoulos, Hagen Ott, Stephanie Hompes, Maria Beatrice Bilò, Blanca E. García, Margitta Worm
Pubblicato in: Allergy, Numero 80, 2025, Pagina/e 2837-2848, ISSN 0105-4538
Editore: Blackwell Publishing Inc.
DOI: 10.1111/all.16619

Allele-Specific Disruption of a Common STAT3 Autosomal Dominant Allele Is Not Sufficient to Restore Downstream Signaling in Patient-Derived T Cells

Autori: Saskia König, Manfred Fliegauf, Manuel Rhiel, Bodo Grimbacher, Tatjana I. Cornu, Toni Cathomen, Claudio Mussolino
Pubblicato in: Genes, Numero 13, 2025, Pagina/e 1912, ISSN 2073-4425
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes13101912

Molecular mechanisms underlying NLRP3 inflammasome activation and IL-1β production in air pollution fine particulate matter (PM2.5)-primed macrophages

Autori: Lourdes Caceres, Tijani Abogunloko, Sara Malchow, Fabienne Ehret, Julian Merz, Xiaowei Li, Lucia Sol Mitre, Natalia Magnani, Deborah Tasat, Timothy Mwinyella, Lisa Spiga, Dymphie Suchanek, Larissa Fischer, Oliver Gorka, Mark Colin Gissler, Ingo Hilgendorf, Peter Stachon, Eva Rog-Zielinska, Olaf Groß, Dirk Westermann, Pablo Evelson, Dennis Wolf, Timoteo Marchini
Pubblicato in: Environmental Pollution, Numero 341, 2025, Pagina/e 122997, ISSN 0269-7491
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2023.122997

Other (1)

DNA damage signaling in<i>Drosophila</i>macrophages modulates systemic cytokine levels in response to oxidative stress

Autori: Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S. Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf
Pubblicato in: 2024
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.02.22.529599