Project description
Significance of gut microbiota in inflammatory bowel diseases
Immune-related inflammatory bowel diseases (IBD) include Crohn’s disease and ulcerative colitis, disorders characterised by gut inflammation. IBD incidence has increased in Western countries in recent decades, pointing to the role of environmental factors. The condition of gut microbiota and an alteration in intestinal and immune cell energy metabolism have been linked to the pathogenesis of IBD. The EU-funded ENERGISED project aims to identify the microorganisms and their metabolites impacting energy metabolism in the host cells and understand the significance of gut microbiota and metabolism alterations in IBD pathogenesis. The project objective is to design novel microbiota-based therapeutic strategies to regulate the host cell energy state in IBD cases.
Fields of science
- medical and health sciencesclinical medicinegastroenterologyinflammatory bowel disease
- medical and health sciencesbasic medicineimmunology
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensors
- natural sciencesbiological sciencesmicrobiology
Programme(s)
- HORIZON.1.1 - European Research Council (ERC) Main Programme
Funding Scheme
ERC - Support for frontier research (ERC)
Coordinator
75006 Paris
France
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Participants (2)
75000 Paris
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75007 Paris Cedex 07
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