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ModulatIng Cancer therapy RespOnse using Bacterial Extracellular nanovesicles

Project description

Bacterial extracellular vesicles against cancer

Like eukaryotic cells, bacteria secrete nanometre-sized extracellular vesicles (BEVs) loaded with active cargo such as proteins as a mechanism of communication with other bacteria and with the host. Scientists under the EU-funded MICROBE project had previously discovered that gut microbiota also secrete BEVs in the systemic circulation of patients with increased intestinal permeability. The biological significance of BEVs in the interplay between the host and bacteria is still largely unknown. Through in-depth characterisation of BEVs from healthy individuals and patients with increased intestinal permeability, MICROBE aims to investigate how BEVs influence the disease course.

Coordinator

UNIVERSITEIT GENT
Net EU contribution
€ 2 000 000,00
Address
Sint Pietersnieuwstraat 25
9000 Gent
Belgium

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Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00