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Combining Artificial Intelligence and smart sensing TOward better management and improved quality of LIFE in chronic obstructive pulmonary disease

Objective

Chronic obstructive pulmonary disease (COPD) is a highly prevalent chronic condition. While COPD is a lung disease, it is mainly the exacerbations and extrapulmonary comorbidities which affect the quality of life, health care costs, and prognosis. The optimal COPD treatment needs to focus on both the characteristics and consequences of the lung disease itself and the diagnosis and treatment of comorbidities. While the severity of lung function impairment is routinely assessed, the exacerbations, the associated comorbidities and limitations in daily life are still significantly underestimated. A personalized approach to COPD management is needed to specifically address the disease, prevent exacerbations, and mitigate its comorbidities to obtain a positive impact on patient health and quality of life.
TOLIFE will clinically validate an artificial intelligence (AI) solution to process daily life patient data captured by unobtrusive sensors to enable optimised personalised treatment, assessment of health outcomes and improved quality of life in COPD patients. The TOLIFE approach to COPD management, targeted to predict and mitigate exacerbations and continuously assess the health outcomes, has the potential to reduce mortality, improve health related quality of life and reduce the healthcare costs.
TOLIFE will develop and clinically validate an AI-based platform for the early prediction of exacerbations and assessment of the health outcomes. Prediction of exacerbations and assessment of health outcomes will be exploited by clinicians through a patient management tool to perform early and personalized treatment. TOLIFE platform will inform through a disease information tool the patient and caregivers about the patient's health status, the specific treatment plan and lifestyle indications. Two clinical studies will be implemented, one to collect data for AI-tools development and the other to validate the effectiveness of TOLIFE to reduce the risk of exacerbations.

Coordinator

UNIVERSITA DI PISA
Net EU contribution
€ 1 245 937,50
Address
Lungarno Pacinotti 43/44
56126 Pisa
Italy

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Region
Centro (IT) Toscana Pisa
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (13)

CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
Net EU contribution
€ 753 187,50
Address
Piazzale Aldo Moro 7
00185 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Non-EU contribution
€ 0,00
TIME.LEX
Belgium
Net EU contribution
€ 196 250,00
Address
Joseph Stevensstraat 7
1000 Brussel

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
ISTITUTO SUPERIORE DI SANITA
Italy
Net EU contribution
€ 136 625,00
Address
Viale Regina Elena 299
00161 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Non-EU contribution
€ 0,00
BEWARRANT
Belgium
Net EU contribution
€ 248 375,00
Address
Avenue Henri Jaspar 113
1060 Bruxelles

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

WARRANT HUB SPA
Italy
Net EU contribution
€ 103 500,00
Address
Corso Mazzini 11
42015 Correggio Re

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nord-Est Emilia-Romagna Reggio nell’Emilia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
UNIVERSIDAD POLITECNICA DE MADRID
Spain
Net EU contribution
€ 626 000,00
Address
Calle Ramiro De Maeztu 7 Edificio Rectorado
28040 Madrid

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
TECHEDGE ESPANA SL
Spain
Net EU contribution
€ 431 250,00
Address
Calle Martinez Villergas 52 Edificio B 6a Planta
28027 Madrid

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

TECHEDGE SPA
Italy
Net EU contribution
€ 277 000,00
Address
Via Caldera 21
20153 Milano

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Region
Nord-Ovest Lombardia Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spain
Net EU contribution
€ 621 382,00
Address
C Rossello 132 Planta 05
08036 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,50
PENUMOLOGISCHES FORSCHUNGSINSTITUTAN DER LUNGENCLINIC GROSSHANSDORF GMBH
Germany
Net EU contribution
€ 629 500,00
Address
Wohrendamm 80
22927 Grosshansdorf

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Schleswig-Holstein Schleswig-Holstein Stormarn
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
EUROPEAN FEDERATION OF ASTHMA &ALLERGY ASSOCIATIONS IDEELL FORENING
Sweden
Net EU contribution
€ 122 250,00
ADATEC SENSING & AUTOMATION SRL
Italy
Net EU contribution
€ 220 625,00
Address
Via Delle Rose 105
55100 Lucca

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Centro (IT) Toscana Lucca
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CONSORCIO MAR PARC DE SALUT DE BARCELONA
Spain
Net EU contribution
€ 376 977,00
Address
Paseo Maritim 25-29
08003 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Non-EU contribution
€ 0,50