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Epigenetic regulation of host factors in viral infections (EPIVINF)

Project description

Mechanisms of host epigenetic alterations during viral infection

The EU-funded EPIVINF project aims to understand how acute viral infections alter the epigenetic regulation of host factors, governing immune control and neurological health. The study will focus on the HIV and SARS-CoV-2 human viral pathogens that affect people around the world and share common features that require further research. The researchers will employ advanced epigenetic analyses, immune monitoring, relevant animal models, samples from HIV and Covid-19 vaccine trials and integrated biosystem analyses to investigate how infections harness epigenetic mechanisms to change the adaptive and innate immune response and how these mechanisms may impact neurological health. The study also aims to identify the predisposing factors leading to specific clinical symptoms and how these could be employed as novel therapeutic targets.

Coordinator

FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA
Net EU contribution
€ 2 244 625,00
Address
Carretera De Canyet
08916 Barcelona
Spain

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Other funding
€ 0,00

Participants (5)

KAROLINSKA INSTITUTET
Sweden
Net EU contribution
€ 729 531,00
Address
Nobels Vag 5
17177 Stockholm

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,25
OSPEDALE SAN RAFFAELE SRL
Italy
Net EU contribution
€ 1 011 875,00
Address
Via Olgettina 60
20132 Milano

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Region
Nord-Ovest Lombardia Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
UNIVERSITAT DES SAARLANDES
Germany
Net EU contribution
€ 809 750,00
Address
Campus
66123 Saarbrucken

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Region
Saarland Saarland Regionalverband Saarbrücken
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
OMNISCOPE LIMITED
Malta
Net EU contribution
€ 1 538 137,00
Address
30/1, Kenilworth Court, Sir Augustus Bartolo Stree
XBX 1093 Ta Xbiex

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Malta Malta Malta
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,50
INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES
Spain
Net EU contribution
€ 598 390,00
Address
Ctra C-59 Km 12 Torre Marimon
08140 Caldes De Montbui Barcelona

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Region
Este Cataluña Barcelona
Activity type
Other
Other funding
€ 0,00