Precision drug REPurpOsing For EUrope and the world

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REPO4EU Open Science Strategy
Initial whitepaper on a virtual EU biobank platform for patient recruitment pilots
REPO4EU Impact Master Plan - Document detailing the project's official dissemination and communication plans, and the outline of target groups and their segments for community building purposes.

REPO4EU Impact Master Plan – Document detailing the project’s official dissemination and communication plans, and the outline of target groups and their segments for community building purposes.

Generic guideline for conducting an extended FtO analysis and FtO analyses for all intended clinical trials
An inventory of internal and external initial external stakeholder survey to collect needs in drug repurposing, and their objectives and expectations regarding FtO, IP and BD
Initial whitepaper on rational and first selection of animal models for drug repurposing
Initial whitepaper on rational for a wet-lab technology platform for patient recruitment
Initial whitepaper on rational for an AI technology platform for patient recruitment

Publishing portal launch

Publications

Seminars in Immunopathology

Auteurs: Szepanowski RD, Haupeltshofer S, Vonhof SE, Frank B, Kleinschnitz C, Casas AI
Publié dans: Seminars in Immunopathology, Numéro 45, 2023, ISSN 1863-2297
Éditeur: Springer
DOI: 10.1007/s00281-023-00994-4

Journal of Alzheimer's Disease

Auteurs: Mayra Pacheco Pachado, Ana I Casas, Mahmoud H Elbatreek, Cristian Nogales, Emre Guney, Alberto J Espay, Harald H H W Schmidt
Publié dans: Journal of Alzheimer’s Disease, Numéro 96, 2023, ISSN 1387-2877
Éditeur: IOS Press
DOI: 10.3233/JAD-230694

Molecular interaction networks and drug development: novel approach to drug target identification and drug repositioning

Auteurs: Loscalzo J
Publié dans: FASEB J, Numéro 37, 2023, ISSN 1530-6860
Éditeur: Wiley
DOI: 10.1096/fj.202201683R

Multiomics network medicine approaches to precision medicine....

Auteurs: Wang RS, Maron BA, Loscalzo J
Publié dans: Arterioscler Thromb Vasc Biol, Numéro 43, 2023, ISSN 1079-5642
Éditeur: Lippincott, Williams & Wilkins
DOI: 10.1161/ATVBAHA.122.318731

scDrugPrio: a framework for analysis of single-cell transcriptomics....

Auteurs: Schaefer S, Smelik M, Sysoev O, Zhao Y, Eklund D, et al.
Publié dans: Genome Med, Numéro 16, 2024, ISSN 1756-994X
Éditeur: (London) BioMed Central
DOI: 10.1101/2023.11.08.566249

Repurposing drugs for the treatment of COVID-19....

Auteurs: Wang RS, Loscalzo J
Publié dans: Circ Res, Numéro 132, 2023, ISSN 0009-7330
Éditeur: Lippincott, Williams & Wilkins
DOI: 10.1161/CIRCRESAHA.122.321879

Phenomics and robust multiomics data for cardiovascular disease subtyping

Auteurs: Maiorino E, Loscalzo J
Publié dans: Arterioscler Thromb Vasc Biol, Numéro 43, 2023, ISSN 1079-5642
Éditeur: Lippincott, Williams & Wilkins
DOI: 10.1161/ATVBAHA.122.318892

Machine learning-based integration of network features and chemical structures of compounds....

Auteurs: Spaeth J, Wang RS, Humphrey M, Baumbach J, Loscalzo J
Publié dans: CPT Pharmacometrics Syst Pharmacol, Numéro 13, 2024, ISSN 2163-8306
Éditeur: Wiley
DOI: 10.1002/psp4.13076

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