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CORDIS - EU research results
CORDIS

Precision drug REPurpOsing For EUrope and the world

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Publications

A system perspective on drug response (opens in new window)

Author(s): Vlad Elgart, Joseph Loscalzo
Published in: British Journal of Pharmacology, 2025, ISSN 0007-1188
Publisher: Wiley
DOI: 10.1111/BPH.70128

Artificial Intelligence and Network Medicine: Path to Precision Medicine (opens in new window)

Author(s): Lucia Altucci, Lina Badimon, Jean-Luc Balligand, Jan Baumbach, Alberico L. Catapano, Feixong Cheng, Dawn DeMeo, Rajat Gupta, Marcus Hacker, Yang-Yu Liu, Joseph Loscalzo, Sabrina Maniscalco, Jörg Menche, Giulia Menichetti, Paolo Parini, Harald H. H. W. Schmidt, Marinka Zitnik
Published in: NEJM AI, Issue 2, 2025, ISSN 2836-9386
Publisher: Massachusetts Medical Society
DOI: 10.1056/AIRA2401229

Seminars in Immunopathology (opens in new window)

Author(s): Szepanowski RD, Haupeltshofer S, Vonhof SE, Frank B, Kleinschnitz C, Casas AI
Published in: Seminars in Immunopathology, Issue 45, 2023, ISSN 1863-2297
Publisher: Springer
DOI: 10.1007/s00281-023-00994-4

Drugst.One — a plug-and-play solution for online systems medicine and network-based drug repurposing (opens in new window)

Author(s): Andreas Maier, Michael Hartung, Mark Abovsky, Klaudia Adamowicz, Gary D Bader, Sylvie Baier, David B Blumenthal, Jing Chen, Maria L Elkjaer, Carlos Garcia-Hernandez, Mohamed Helmy, Markus Hoffmann, Igor Jurisica, Max Kotlyar, Olga Lazareva, Hagai Levi, Markus List, Sebastian Lobentanzer, Joseph Loscalzo, Noel Malod-Dognin, Quirin Manz, Julian Matschinske, Miles Mee, Mhaned Oubounyt, Chiara Pastrello, Alexander R Pico, Rudolf T Pillich, Julian M Poschenrieder, Dexter Pratt, Nataša Pržulj, Sepideh Sadegh, Julio Saez-Rodriguez, Suryadipto Sarkar, Gideon Shaked, Ron Shamir, Nico Trummer, Ugur Turhan, Rui-Sheng Wang, Olga Zolotareva, Jan Baumbach
Published in: Nucleic Acids Research, Issue 52, 2024, ISSN 0305-1048
Publisher: Oxford University Press (OUP)
DOI: 10.1093/NAR/GKAE388

De Novo exposomic geospatial assembly of chronic disease regions with machine learning & network analysis (opens in new window)

Author(s): Andrew Deonarine, Ayushi Batwara, Roy Wada, Puneet Sharma, Joseph Loscalzo, Bisola Ojikutu, Kathryn Hall
Published in: eBioMedicine, Issue 112, 2025, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/J.EBIOM.2025.105575

Journal of Alzheimer's Disease (opens in new window)

Author(s): Mayra Pacheco Pachado, Ana I Casas, Mahmoud H Elbatreek, Cristian Nogales, Emre Guney, Alberto J Espay, Harald H H W Schmidt
Published in: Journal of Alzheimer’s Disease, Issue 96, 2023, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/JAD-230694

Digital twins as global learning health and disease models for preventive and personalized medicine (opens in new window)

Author(s): Xinxiu Li, Joseph Loscalzo, A. K. M. Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky, Marinka Zitnik, Mikael Benson
Published in: Genome Medicine, Issue 17, 2025, ISSN 1756-994X
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S13073-025-01435-7

Molecular interaction networks and drug development: novel approach to drug target identification and drug repositioning (opens in new window)

Author(s): Loscalzo J
Published in: FASEB J, Issue 37, 2023, ISSN 1530-6860
Publisher: Wiley
DOI: 10.1096/fj.202201683R

Multiomics network medicine approaches to precision medicine.... (opens in new window)

Author(s): Wang RS, Maron BA, Loscalzo J
Published in: Arterioscler Thromb Vasc Biol, Issue 43, 2023, ISSN 1079-5642
Publisher: Lippincott, Williams & Wilkins
DOI: 10.1161/ATVBAHA.122.318731

scDrugPrio: a framework for analysis of single-cell transcriptomics.... (opens in new window)

Author(s): Schaefer S, Smelik M, Sysoev O, Zhao Y, Eklund D, et al.
Published in: Genome Med, Issue 16, 2024, ISSN 1756-994X
Publisher: (London) BioMed Central
DOI: 10.1101/2023.11.08.566249

Network‐based precision medicine and systems pharmacology (opens in new window)

Author(s): Arvind K. Pandey, Susan Dina Ghiassian, Joseph Loscalzo
Published in: British Journal of Pharmacology, 2025, ISSN 0007-1188
Publisher: Wiley
DOI: 10.1111/BPH.70184

Revising EU pharmaceutical legislation: will it foster drug repurposing? (opens in new window)

Author(s): Mirre Scholte, Sabine E. Grimm, Bianca Pauly, Frank Verbeeck, Anna M.G. Pasmooij, Barend Bouma, Jorika van Duijn-Wiersma, Emre Guney, Aaron S. Kesselheim, Harald H.H.W. Schmidt, Manuela A. Joore
Published in: Drug Discovery Today, Issue 30, 2025, ISSN 1359-6446
Publisher: Elsevier BV
DOI: 10.1016/J.DRUDIS.2024.104286

Repurposing drugs for the treatment of COVID-19.... (opens in new window)

Author(s): Wang RS, Loscalzo J
Published in: Circ Res, Issue 132, 2023, ISSN 0009-7330
Publisher: Lippincott, Williams & Wilkins
DOI: 10.1161/CIRCRESAHA.122.321879

Phenomics and robust multiomics data for cardiovascular disease subtyping (opens in new window)

Author(s): Maiorino E, Loscalzo J
Published in: Arterioscler Thromb Vasc Biol, Issue 43, 2023, ISSN 1079-5642
Publisher: Lippincott, Williams & Wilkins
DOI: 10.1161/ATVBAHA.122.318892

Machine learning-based integration of network features and chemical structures of compounds.... (opens in new window)

Author(s): Spaeth J, Wang RS, Humphrey M, Baumbach J, Loscalzo J
Published in: CPT Pharmacometrics Syst Pharmacol, Issue 13, 2024, ISSN 2163-8306
Publisher: Wiley
DOI: 10.1002/psp4.13076

How Can Health Technology Assessment Help in Addressing Drug Repurposing Challenges? A Conceptual Framework (opens in new window)

Author(s): T. Abu-Zahra, S. Grimm, M. Scholte, M. Joore
Published in: Value in Health, 2023
Publisher: ElSevier
DOI: 10.1016/j.jval.2023.09.1865

CAUSAL DISCOVERY : FINDING COMMON LATENT CAUSES

Author(s): Xanthopoulou-Koukogia, K.
Published in: 2023
Publisher: University Twente

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