Precision drug REPurpOsing For EUrope and the world

Informazioni relative al progetto

REPO4EU

ID dell’accordo di sovvenzione: 101057619

DOI 10.3030/101057619

Data della firma CE 24 Maggio 2022

Data di avvio 1 Settembre 2022

Data di completamento 31 Agosto 2029

Finanziato da

• Health

Costo totale € 22 982 612,00

Contributo UE € 22 982 612,00

Coordinato da

UNIVERSITEIT MAASTRICHT
Netherlands

Risultati finali

Documents, reports (8)

REPO4EU Open Science Strategy
Initial whitepaper on a virtual EU biobank platform for patient recruitment pilots
REPO4EU Impact Master Plan - Document detailing the project's official dissemination and communication plans, and the outline of target groups and their segments for community building purposes.

REPO4EU Impact Master Plan – Document detailing the project’s official dissemination and communication plans, and the outline of target groups and their segments for community building purposes.

Generic guideline for conducting an extended FtO analysis and FtO analyses for all intended clinical trials
An inventory of internal and external initial external stakeholder survey to collect needs in drug repurposing, and their objectives and expectations regarding FtO, IP and BD
Initial whitepaper on rational and first selection of animal models for drug repurposing
Initial whitepaper on rational for a wet-lab technology platform for patient recruitment
Initial whitepaper on rational for an AI technology platform for patient recruitment

Other (1)

Publishing portal launch

Pubblicazioni

Peer reviewed articles (8)

Seminars in Immunopathology

Autori: Szepanowski RD, Haupeltshofer S, Vonhof SE, Frank B, Kleinschnitz C, Casas AI
Pubblicato in: Seminars in Immunopathology, Numero 45, 2023, ISSN 1863-2297
Editore: Springer
DOI: 10.1007/s00281-023-00994-4

Journal of Alzheimer's Disease

Autori: Mayra Pacheco Pachado, Ana I Casas, Mahmoud H Elbatreek, Cristian Nogales, Emre Guney, Alberto J Espay, Harald H H W Schmidt
Pubblicato in: Journal of Alzheimer’s Disease, Numero 96, 2023, ISSN 1387-2877
Editore: IOS Press
DOI: 10.3233/JAD-230694

Molecular interaction networks and drug development: novel approach to drug target identification and drug repositioning

Autori: Loscalzo J
Pubblicato in: FASEB J, Numero 37, 2023, ISSN 1530-6860
Editore: Wiley
DOI: 10.1096/fj.202201683R

Multiomics network medicine approaches to precision medicine....

Autori: Wang RS, Maron BA, Loscalzo J
Pubblicato in: Arterioscler Thromb Vasc Biol, Numero 43, 2023, ISSN 1079-5642
Editore: Lippincott, Williams & Wilkins
DOI: 10.1161/ATVBAHA.122.318731

scDrugPrio: a framework for analysis of single-cell transcriptomics....

Autori: Schaefer S, Smelik M, Sysoev O, Zhao Y, Eklund D, et al.
Pubblicato in: Genome Med, Numero 16, 2024, ISSN 1756-994X
Editore: (London) BioMed Central
DOI: 10.1101/2023.11.08.566249

Repurposing drugs for the treatment of COVID-19....

Autori: Wang RS, Loscalzo J
Pubblicato in: Circ Res, Numero 132, 2023, ISSN 0009-7330
Editore: Lippincott, Williams & Wilkins
DOI: 10.1161/CIRCRESAHA.122.321879

Phenomics and robust multiomics data for cardiovascular disease subtyping

Autori: Maiorino E, Loscalzo J
Pubblicato in: Arterioscler Thromb Vasc Biol, Numero 43, 2023, ISSN 1079-5642
Editore: Lippincott, Williams & Wilkins
DOI: 10.1161/ATVBAHA.122.318892

Machine learning-based integration of network features and chemical structures of compounds....

Autori: Spaeth J, Wang RS, Humphrey M, Baumbach J, Loscalzo J
Pubblicato in: CPT Pharmacometrics Syst Pharmacol, Numero 13, 2024, ISSN 2163-8306
Editore: Wiley
DOI: 10.1002/psp4.13076