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CORDIS - Resultados de investigaciones de la UE
CORDIS

Transforming into a sustainable European pharmaceutical sector

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Plan for Stakeholder Engagement (se abrirá en una nueva ventana)

Initial report on stakeholder needs and interests related to TransPharm project.

Plan for Dissemination, Communication and Exploitation of Results (se abrirá en una nueva ventana)

PSEDER will include (i) mapping of stakeholders / specific target groups; (ii) key exploitation / dissemination opportunities per target group; (iii) definition of project communication strategy; (iv) measures and activities for reaching each target group, with a time plan for implementation; (v) measurable control points and activities’ assessment; (vi) dissemination database with stakeholders at national/European level.

Project website (se abrirá en una nueva ventana)

Setup project website to be updated regularly with outcomes of WP1, WP2, WP3, WP4, WP5 and WP6.

Report on stakeholder needs and interests related to TransPharm tools/methods (se abrirá en una nueva ventana)

Report on stakeholder needs and interests related to TransPharm tools/methodsThe report summarises stakeholder requirements identified in interviews / online survey, and matches them with an overview of TransPharm tools/methods, including a first specification of which requirements could be more easily incorporated in them and which are more challenging.

Stakeholder views, needs & wishes on sustainability assessment of APIs (se abrirá en una nueva ventana)

The report provides an overview of stakeholder views, needs and wishes in relation to the sustainability assessment of pharmaceuticals, based on interviews, surveys and/or focus groups, as well as their views regarding the draft assessment approach, the draft value chain map and potential trade-offs.

Methodologies to fill LCI data gaps for prospective and retrospective assessments (se abrirá en una nueva ventana)

Lessons learned on methodologies to fill LCI data gaps for prospective and retrospective assessments will be described as input for the case studies (project internal documents on the project sharepoint) and as input for the guidance on integrated sustainability assessment of pharaceuticals (D4.5, integral general text and appendix for technical details).

Guidelines for reduction of nitrosamine and transition metal contamination in pharmaceuticals (se abrirá en una nueva ventana)

Research-based recommendations for reducing N-nitrosamine impurities and transition metal contamination in synthetic active pharmaceutical ingredients.

Databases used for training the models, accessible in excel format or through a web tool (se abrirá en una nueva ventana)

Well-curated databases using canonical SMILES and InChI to as unique molecular identifiers. For reactions, reaction SMILES or SMIRKS will be used. The databases will be stored in NoSQL format that can be exported to a user-friendly interface, such as excel.

Publicaciones

Water brownness regulates the bioavailability of a fluoroquinolone antibiotic: UV-absorbance as a predictor of ciprofloxacin ecotoxicity (se abrirá en una nueva ventana)

Autores: Qiyun Zhanga, Kristof Demeestere, Karel A.C. De Schamphelaere
Publicado en: Environmental Pollution, Edición 334, 2023, ISSN 1873-6424
Editor: ScienceDirect
DOI: 10.1016/j.envpol.2023.122209

Eco-pharma dilemma: Navigating environmental sustainability trade-offs within the lifecycle of pharmaceuticals – A comment (se abrirá en una nueva ventana)

Autores: Caroline T.A. Moermond, Neele Puhlmann, Lowik Pieters, Avtar Matharu, Lieselot Boone, Maarten Dobbelaere, Héloïse Proquin, Klaus Kümmerer, Ad M.J. Ragas, Rodrigo Vidaurre, Bastiaan Venhuis, Delphine De Smedt
Publicado en: Sustainable Chemistry and Pharmacy, Edición 43, 2025, ISSN 2352-5541
Editor: Elsevier BV
DOI: 10.1016/J.SCP.2024.101893

Scalable synthesis of 3-O functionalized deoxyribonolactones from biorenewable levoglucosenone (se abrirá en una nueva ventana)

Autores: Maarten Debruyne, Martha C. Mayorquín-Torres, Jason E. Camp, Christian V. Stevens
Publicado en: Arkivoc, Edición 2024, 2025, ISSN 1551-7012
Editor: ARKAT USA, Inc.
DOI: 10.24820/ARK.5550190.P012.378

Tandem Cu(I)-Catalyzed Dipolar Cycloaddition–C–H Activation for the In-Flow Synthesis of <i>N</i>-Pyridyl-5-amino-1,2,3-triazole-4-carboxylates (se abrirá en una nueva ventana)

Autores: Emanuela Donato, Martha C. Mayorquín-Torres, Alessandra Puglisi, Maurizio Benaglia, Mauro F. A. Adamo, Christian V. Stevens
Publicado en: Organic Letters, Edición 27, 2025, ISSN 1523-7060
Editor: American Chemical Society (ACS)
DOI: 10.1021/ACS.ORGLETT.5C00453

Geometric deep learning for molecular property predictions with chemical accuracy across chemical space (se abrirá en una nueva ventana)

Autores: Maarten R. Dobbelaere, István Lengyel, Christian V. Stevens, Kevin M. Van Geem
Publicado en: Journal of Cheminformatics, Edición 16, 2024, ISSN 1758-2946
Editor: Springer Science and Business Media LLC
DOI: 10.1186/S13321-024-00895-0

Mapping the risk of ciprofloxacin in European water bodies: Incorporating the impact of bioavailability (se abrirá en una nueva ventana)

Autores: Qiyun Zhang, Kristof Demeestere, Karel A.C. De Schamphelaere
Publicado en: Science of The Total Environment, Edición 955, 2025, ISSN 0048-9697
Editor: Elsevier BV
DOI: 10.1016/J.SCITOTENV.2024.177202

Rxn-INSIGHT: fast chemical reaction analysis using bond-electron matrices (se abrirá en una nueva ventana)

Autores: Maarten R. Dobbelaere, István Lengyel, Christian V. Stevens, Kevin M. Van Geem
Publicado en: Journal of Cheminformatics, Edición 16, 2024, ISSN 1758-2946
Editor: Springer Science and Business Media LLC
DOI: 10.1186/S13321-024-00834-Z

Applicability of the European Commission’s framework on safe and sustainable by design to the pharmaceutical sector (se abrirá en una nueva ventana)

Autores: Neele Puhlmann, Elisabetta Abbate, Klaus Kümmerer, Agnes G. Oomen, Ad M.J. Ragas, Caroline Moermond
Publicado en: Sustainable Chemistry and Pharmacy, Edición 42, 2024, ISSN 2352-5541
Editor: Elsevier BV
DOI: 10.1016/J.SCP.2024.101845

A holistic framework for integrated sustainability assessment of pharmaceuticals (se abrirá en una nueva ventana)

Autores: Lisa Van Wilder, Lieselot Boone, Ad Ragas, Caroline Moermond, Lowik Pieters, Aissa Rechlin, Rodrigo Vidaurre, Delphine De Smedt, Jo Dewulf
Publicado en: Journal of Cleaner Production, Edición 467, 2024, ISSN 0959-6526
Editor: Elsevier BV
DOI: 10.1016/J.JCLEPRO.2024.142978

Keystones in the implementation of greener pharmaceuticals: A scoping review (se abrirá en una nueva ventana)

Autores: Ella D. van Vliet, Nynke M. Kannegieter, Caroline T.A. Moermond, Teresa Leonardo Alves
Publicado en: Sustainable Chemistry and Pharmacy, Edición 44, 2025, ISSN 2352-5541
Editor: Elsevier BV
DOI: 10.1016/J.SCP.2025.101938

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