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CORDIS - Resultados de investigaciones de la UE
CORDIS

eBRAIN-Health - Actionable Multilevel Health Data

Descripción del proyecto

Encéfalos virtuales para la investigación

La complejidad del encéfalo humano plantea un reto importante a la investigación y, por tanto, a la comprensión de los mecanismos que rigen su funcionamiento y disfunción. Los gemelos digitales son modelos virtuales diseñados para reflejar objetos físicos y ofrecen un método interesante para la investigación neurocientífica. El equipo del proyecto eBRAIN-Health, financiado con fondos europeos, generará este tipo de modelos virtuales de pacientes y personas sanas de referencia para estudiar la demencia, un importante problema médico y social. Los investigadores procesarán y combinarán datos moleculares, celulares, fisiológicos y conductuales en una infraestructura de investigación clínica. La simulación del encéfalo humano ayudará a predecir el riesgo de demencia, así como a desarrollar innovaciones sanitarias.

Objetivo

The Project eBrain-Health will deliver a distributed research platform for modeling and simulating complex neurobiological phenomena of human brain function and dysfunction in a data protection compliant environment. It will provide thousands of multilevel virtual brains from patients and healthy human controls for research and innovation. Brain data from multiple sources will be pre-processed. Solving the societal grand challenge of dementia is a big task. Yet it appears feasible in a collective approach. Therefore, we will build an interdisciplinary digital twin for dementia for modeling and simulating complex phenomena at the service of research infrastructure communities. EBRAINS-Health-Cloud will offer end-to-end services for personalized complex brain modeling and simulations in distributed e-infrastructures with data protection by design and by default and simulation-ready human multiscale brain data that range from molecular (genomics, proteomics, metabolomics) and cellular to electrophysiology and imaging to behavioural, clinical, life-style and environmental data as well as data from wearables. Brain data are pre-processed and annotated such that they all relate to a common reference 3D brain space. EBRAINS-Health-Cloud constitutes a blend of three large-scale research programs: the FET Flagship Human Brain Project with its EBRAINS Research Infrastructure, the EOSC project Virtual Brain Cloud with its Virtual Research Environment for sensitive data and the H2020 project AI-MIND with intelligent tools for dementia risk estimation. The project will have synergies to topics of the Digital Europe Program, such as artificial intelligence, cybersecurity and supercomputing and the Health Data Space. EBRAINS-Health-Cloud offers a next generation clinical research infrastructure and creates an open yet protected space for groundbreaking digital health innovation by the research infrastructure communities comprising academia and the private sector.

Coordinador

CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Aportación neta de la UEn
€ 1 396 250,00
Dirección
Chariteplatz 1
10117 Berlin
Alemania

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Región
Berlin Berlin Berlin
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
€ 1 396 250,00

Participantes (17)

Socios (2)