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eBRAIN-Health - Actionable Multilevel Health Data

Descrizione del progetto

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Cervelli virtuali per la ricerca

La complessità del cervello umano rappresenta una sfida significativa per lo studio, e dunque per la comprensione, dei meccanismi che regolano la sua funzione e disfunzione. I gemelli digitali, ovvero modelli virtuali progettati per riflettere gli oggetti fisici, rappresentano un approccio interessante alla ricerca neuroscientifica. Il progetto eBRAIN-Health, finanziato dall’UE, genererà modelli virtuali di pazienti e soggetti di controllo sani con l’obiettivo di studiare la demenza, una problematica sociale e sanitaria di grande rilevanza. Il team di ricerca elaborerà e combinerà dati molecolari, cellulari, fisiologici e comportamentali in un’infrastruttura di ricerca clinica. La simulazione del cervello umano contribuirà a prevedere il rischio di demenza e a sviluppare innovazioni sanitarie.

Obiettivo

The Project eBrain-Health will deliver a distributed research platform for modeling and simulating complex neurobiological phenomena of human brain function and dysfunction in a data protection compliant environment. It will provide thousands of multilevel virtual brains from patients and healthy human controls for research and innovation. Brain data from multiple sources will be pre-processed. Solving the societal grand challenge of dementia is a big task. Yet it appears feasible in a collective approach. Therefore, we will build an interdisciplinary digital twin for dementia for modeling and simulating complex phenomena at the service of research infrastructure communities. EBRAINS-Health-Cloud will offer end-to-end services for personalized complex brain modeling and simulations in distributed e-infrastructures with data protection by design and by default and simulation-ready human multiscale brain data that range from molecular (genomics, proteomics, metabolomics) and cellular to electrophysiology and imaging to behavioural, clinical, life-style and environmental data as well as data from wearables. Brain data are pre-processed and annotated such that they all relate to a common reference 3D brain space. EBRAINS-Health-Cloud constitutes a blend of three large-scale research programs: the FET Flagship Human Brain Project with its EBRAINS Research Infrastructure, the EOSC project Virtual Brain Cloud with its Virtual Research Environment for sensitive data and the H2020 project AI-MIND with intelligent tools for dementia risk estimation. The project will have synergies to topics of the Digital Europe Program, such as artificial intelligence, cybersecurity and supercomputing and the Health Data Space. EBRAINS-Health-Cloud offers a next generation clinical research infrastructure and creates an open yet protected space for groundbreaking digital health innovation by the research infrastructure communities comprising academia and the private sector.

Campo scientifico

Parole chiave

Programma(i)

Argomento(i)

Invito a presentare proposte

HORIZON-INFRA-2021-TECH-01

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Meccanismo di finanziamento

HORIZON-RIA - HORIZON Research and Innovation Actions

Coordinatore

CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Contribution nette de l'UE
€ 1 396 250,00
Indirizzo
Chariteplatz 1
10117 Berlin
Germania

Mostra sulla mappa
Regione
Berlin Berlin Berlin
Tipo di attività
Higher or Secondary Education Establishments
Collegamenti
Costo totale
€ 1 396 250,00

Partecipanti (17)

Partner (2)

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Ultimo aggiornamento: 5 Aprile 2023

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Permalink: https://cordis.europa.eu/project/id/101058516/it

European Union, 2024