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Leistungen
The proposal describes the planned measures to maximize the impact of the project, including the dissemination and exploitation measures that are planned:- Regarding results dissemination in a short term, and considering the importance of the objectives, I expect my data to be published in very high impact factor journals (Nature, Science, Cell). The French scientific community working on GPCRs will be informed rapidly via short communication or oral presentations, as all host lab members belong to the International Research Network on GPCRs (iGPCRnet) which organize events every year. I also expect the results to be shared with the international scientific community via oral communications in large audience international conferences such as Gordon Conferences (Molecular Pharmacology, Italy, 2022), International Microscopy Congress (IMC20, Korea, 2023) or Keystone symposia (GPCRs, USA, 2022). These conferences will stimulate new collaborations with academic laboratories and pharmaceutical companies throughout the world. It is important to communicate to the general public to know the science advancements but also to show how the public money is used. Due to the important impact of GPCRs in drug discovery and ultimately to the health of patients, the host team already did several communications at a local or national level, either via the portals of our institutes, research organisms, or via printed media, as already done for past discoveries of the host members (i.e: https://www.igf.cnrs.fr/index.php/fr/actus-fr/192-actus-12-10-2017-fr) or more recently (https://www.igf.cnrs.fr/index.php/fr/actus-fr/256-actus-27-05-2021-fr) and also via national visibility (https://www.inserm.fr/magazine/inserm-le-magazine-n50). I will thus use those communication methods to largely diffuse my work and results to disseminate them locally but also internationally.- The use of animal toxins to develop new drugs is very attractive for a large audience. Dr Gilles, a collaborator on the Aim 2, was interviewed many times to present the use of animal toxins for therapeutic use (Journal of France 2, Journal of TF1, Futuremag (ARTE), Science Et Vie, Psychologies magazine, Le Monde, El Mundo). These international and national media already encouraged the host team to contact them again if a new story with toxins appears. I will contact these media and others as soon as significant results will be generated by the 3D-V2R project.- As a scientist, I feel it is incredibly important to communicate and share my passion for scientific endeavours with the lay public. It is also important to justify how public money is spent for scientific discoveries. To this end, I will closely work with the CNRS communication offices to prepare press releases of research results. To target a general audience, I also plan to participate to “Fête de la Science”, “Pint of Science”, and to either schoolchildren via the program “Déclic” or to a broader student public at the “Université du Tiers Temps” de Montpellier. In addition, I will join the IGF ‘Destination lab’ actions that allow groups of pupils to visit labs for one day. I will specifically advocate for schools in lower income areas to be targeted by these actions, to give an opportunity to underprivileged students to discover the world of research.
Data Management Plan (öffnet in neuem Fenster)The Data Management Plan describes the data management life cycle for all data sets that will be collected processed or generated by the action It is a document describing what data will be collected processed or generated and following what methodology and standards whether and how this data will be shared andor made open and how it will be curated and preserved
Veröffentlichungen
Autoren:
Aurélien Fouillen, Julien Bous, Pierre Couvineau, Hélène Orcel, Charline Mary, Timothé Pierre, Christiane Mendre, Nicolas Gilles, Gunnar Schulte, Sébastien Granier & Bernard Mouillac
Veröffentlicht in:
2024
Herausgeber:
bioRxiv
Autoren:
Aurélien Fouillen, Pierre Couvineau, Gérald Gaibelet, Stéphanie Riché, Hélène Orcel, Christiane Mendre, Ali Kanso, Romain Lanotte, Julie Nguyen, Juliette Dimon, Serge Urbach, Rémy Sounier, Sébastien Granier, Dominique Bonnet, Xiaojing Cong, Bernard Mouillac, Hélène Déméné
Veröffentlicht in:
Computational and Structural Biotechnology Journal, Ausgabe 23, 2024, ISSN 2001-0370
Herausgeber:
Elsevier BV
DOI:
10.1016/j.csbj.2024.10.039
Autoren:
Aurélien Fouillen, Julien Bous, Sébastien Granier, Bernard Mouillac, Remy Sounier
Veröffentlicht in:
Membranes, 2023, ISSN 2077-0375
Herausgeber:
Molecular Diversity Preservation International
DOI:
10.3390/membranes13060606
Autoren:
Robert D Healey, Louise Couillaud, François Hoh, Assia Mouhand, Aurelien Fouillen, Pierre Couvineau, Sébastien Granier, Cédric Leyrat
Veröffentlicht in:
Communications chemistry, 2023, ISSN 0000-0000
Herausgeber:
Communications chemistry
DOI:
10.1038/s42004-023-00962-x
Autoren:
Bous, Julien; Fouillen, Aurélien; Orcel, Hélène; Trapani, Stefano; Cong, Xiaojing; Fontanel, Simon; Saint-Paul, Julie; Lai-Kee-Him, Joséphine; Urbach, Serge; Sibille, Nathalie; Sounier, Rémy; Granier, Sébastien; Mouillac, Bernard; Bron, Patrick
Veröffentlicht in:
Sci Adv, 2022, ISSN 3605-4364
Herausgeber:
Science Advances
DOI:
10.1126/sciadv.abo7761
Autoren:
Giuseppe Cannone, Ludovic Berto, Fanny Malhaire, Gavin Ferguson, Aurelien Fouillen, Stéphanie Balor, Joan Font-Ingles, Amadeu Llebaria, Cyril Goudet, Abhay Kotecha, Vinothkumar K.R., Guillaume Lebon
Veröffentlicht in:
Nature Communications, Ausgabe 16, 2025, ISSN 2041-1723
Herausgeber:
Springer Science and Business Media LLC
DOI:
10.1038/S41467-024-55439-9
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