A novel Leishmania infantum reference strain for gene editing and the study of visceral leishmaniasis
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Author(s):
Rokhaya Thiam, Maria Santana Ceballos, Tom Beneke, Nada Kuk, Grégoire Pasquier, Lucien Crobu, Daniel C. Jeffares, Baptiste Vergnes, Bridlin Barckmann, Yvon Sterkers
Published in:
PLOS One, Issue 20, 2025, ISSN 1932-6203
Publisher:
Public Library of Science (PLoS)
DOI:
10.1371/JOURNAL.PONE.0327390
Evolutionary adaptations of doublet microtubules in trypanosomatid parasites
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Author(s):
Matthew H. Doran, Qingwei Niu, Jianwei Zeng, Tom Beneke, James Smith, Peter Ren, Sophia Fochler, Adrian Coscia, Johanna L. Höög, Shimi Meleppattu, Polina V. Lishko, Richard J. Wheeler, Eva Gluenz, Rui Zhang, Alan Brown
Published in:
Science, Issue 387, 2025, ISSN 0036-8075
Publisher:
American Association for the Advancement of Science (AAAS)
DOI:
10.1126/SCIENCE.ADR5507
Improved base editing and functional screening in Leishmania via co-expression of the AsCas12a ultra variant, a T7 RNA polymerase, and a cytosine base editor
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Author(s):
Nicole Herrmann May, Anh Cao, Annika Schmid, Fabian Link, Jorge Arias-del-Angel, Elisabeth Meiser, Tom Beneke
Published in:
eLife, Issue 13, 2025, ISSN 2050-084X
Publisher:
eLife Sciences Publications, Ltd
DOI:
10.7554/ELIFE.97437.3
TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen
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Author(s):
Andreia Albuquerque-Wendt, Ciaran McCoy, Rachel Neish, Ulrich Dobramysl, Çağla Alagöz, Tom Beneke, Sally A. Cowley, Kathryn Crouch, Richard J. Wheeler, Jeremy C. Mottram, Eva Gluenz
Published in:
Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher:
Springer Science and Business Media LLC
DOI:
10.1038/S41467-024-55538-7
<i>Leishmania mexicana</i> pathogenicity requires flagellar assembly but not motility
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Author(s):
Tom Beneke, Rachel Neish, Carolina M. C. Catta-Preta, James Smith, Jessica Valli, Ciaran J. McCoy, Andreia Albuquerque-Wendt, Jeremy C. Mottram, Eva Gluenz
Published in:
Virulence, Issue 16, 2025, ISSN 2150-5594
Publisher:
Informa UK Limited
DOI:
10.1080/21505594.2025.2521478