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Inadequate migration of Leishmania-infected macrophages – the driver of parasite dissemination?

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Communication, Dissemination & Outreach Plan (opens in new window)

The plan describes the planned measures to maximize the impact ofthe project, including the dissemination and exploitation measures that are planned,and the target group(s) addressed. Regarding communication measures and publicengagement strategy, the aim is to inform and reach out to society and show theactivities performed, and the use and the benefits the project will have for citizens.

Data Management Plan (opens in new window)

The Data Management Plan describes the data management life cyclefor all data sets that will be collected, processed or generated by the action. It is adocument describing what data will be collected, processed or generated andfollowing what methodology and standards, whether and how this data will beshared and/or made open, and how it will be curated and preserved.

Publications

A novel Leishmania infantum reference strain for gene editing and the study of visceral leishmaniasis (opens in new window)

Author(s): Rokhaya Thiam, Maria Santana Ceballos, Tom Beneke, Nada Kuk, Grégoire Pasquier, Lucien Crobu, Daniel C. Jeffares, Baptiste Vergnes, Bridlin Barckmann, Yvon Sterkers
Published in: PLOS One, Issue 20, 2025, ISSN 1932-6203
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PONE.0327390

Evolutionary adaptations of doublet microtubules in trypanosomatid parasites (opens in new window)

Author(s): Matthew H. Doran, Qingwei Niu, Jianwei Zeng, Tom Beneke, James Smith, Peter Ren, Sophia Fochler, Adrian Coscia, Johanna L. Höög, Shimi Meleppattu, Polina V. Lishko, Richard J. Wheeler, Eva Gluenz, Rui Zhang, Alan Brown
Published in: Science, Issue 387, 2025, ISSN 0036-8075
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIENCE.ADR5507

Improved base editing and functional screening in Leishmania via co-expression of the AsCas12a ultra variant, a T7 RNA polymerase, and a cytosine base editor (opens in new window)

Author(s): Nicole Herrmann May, Anh Cao, Annika Schmid, Fabian Link, Jorge Arias-del-Angel, Elisabeth Meiser, Tom Beneke
Published in: eLife, Issue 13, 2025, ISSN 2050-084X
Publisher: eLife Sciences Publications, Ltd
DOI: 10.7554/ELIFE.97437.3

TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen (opens in new window)

Author(s): Andreia Albuquerque-Wendt, Ciaran McCoy, Rachel Neish, Ulrich Dobramysl, Çağla Alagöz, Tom Beneke, Sally A. Cowley, Kathryn Crouch, Richard J. Wheeler, Jeremy C. Mottram, Eva Gluenz
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-55538-7

<i>Leishmania mexicana</i> pathogenicity requires flagellar assembly but not motility (opens in new window)

Author(s): Tom Beneke, Rachel Neish, Carolina M. C. Catta-Preta, James Smith, Jessica Valli, Ciaran J. McCoy, Andreia Albuquerque-Wendt, Jeremy C. Mottram, Eva Gluenz
Published in: Virulence, Issue 16, 2025, ISSN 2150-5594
Publisher: Informa UK Limited
DOI: 10.1080/21505594.2025.2521478

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