Inadequate migration of Leishmania-infected macrophages – the driver of parasite dissemination?

Información del proyecto

LeishMOM

Identificador del acuerdo de subvención: 101064428

DOI

10.3030/101064428

Proyecto cerrado

Fecha de la firma de la CE 20 Junio 2022

Fecha de inicio 1 Septiembre 2023

Fecha de finalización 31 Agosto 2025

Financiado con arreglo a

• Marie Skłodowska-Curie Actions (MSCA)

Coste total

Sin datos

Aportación de la UE

€ 189 687,36

Coordinado por

JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (1)

Communication, Dissemination & Outreach Plan

The plan describes the planned measures to maximize the impact ofthe project, including the dissemination and exploitation measures that are planned,and the target group(s) addressed. Regarding communication measures and publicengagement strategy, the aim is to inform and reach out to society and show theactivities performed, and the use and the benefits the project will have for citizens.

Data Management Plan (1)

Data Management Plan

The Data Management Plan describes the data management life cyclefor all data sets that will be collected, processed or generated by the action. It is adocument describing what data will be collected, processed or generated andfollowing what methodology and standards, whether and how this data will beshared and/or made open, and how it will be curated and preserved.

Publicaciones

Peer reviewed articles (5)

A novel Leishmania infantum reference strain for gene editing and the study of visceral leishmaniasis

Autores: Rokhaya Thiam, Maria Santana Ceballos, Tom Beneke, Nada Kuk, Grégoire Pasquier, Lucien Crobu, Daniel C. Jeffares, Baptiste Vergnes, Bridlin Barckmann, Yvon Sterkers
Publicado en: PLOS One, Edición 20, 2025, ISSN 1932-6203
Editor: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PONE.0327390

Evolutionary adaptations of doublet microtubules in trypanosomatid parasites

Autores: Matthew H. Doran, Qingwei Niu, Jianwei Zeng, Tom Beneke, James Smith, Peter Ren, Sophia Fochler, Adrian Coscia, Johanna L. Höög, Shimi Meleppattu, Polina V. Lishko, Richard J. Wheeler, Eva Gluenz, Rui Zhang, Alan Brown
Publicado en: Science, Edición 387, 2025, ISSN 0036-8075
Editor: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIENCE.ADR5507

Improved base editing and functional screening in Leishmania via co-expression of the AsCas12a ultra variant, a T7 RNA polymerase, and a cytosine base editor

Autores: Nicole Herrmann May, Anh Cao, Annika Schmid, Fabian Link, Jorge Arias-del-Angel, Elisabeth Meiser, Tom Beneke
Publicado en: eLife, Edición 13, 2025, ISSN 2050-084X
Editor: eLife Sciences Publications, Ltd
DOI: 10.7554/ELIFE.97437.3

TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen

Autores: Andreia Albuquerque-Wendt, Ciaran McCoy, Rachel Neish, Ulrich Dobramysl, Çağla Alagöz, Tom Beneke, Sally A. Cowley, Kathryn Crouch, Richard J. Wheeler, Jeremy C. Mottram, Eva Gluenz
Publicado en: Nature Communications, Edición 16, 2025, ISSN 2041-1723
Editor: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-55538-7

<i>Leishmania mexicana</i> pathogenicity requires flagellar assembly but not motility

Autores: Tom Beneke, Rachel Neish, Carolina M. C. Catta-Preta, James Smith, Jessica Valli, Ciaran J. McCoy, Andreia Albuquerque-Wendt, Jeremy C. Mottram, Eva Gluenz
Publicado en: Virulence, Edición 16, 2025, ISSN 2150-5594
Editor: Informa UK Limited
DOI: 10.1080/21505594.2025.2521478