Inadequate migration of Leishmania-infected macrophages – the driver of parasite dissemination?

Informazioni relative al progetto

LeishMOM

ID dell’accordo di sovvenzione: 101064428

DOI

10.3030/101064428

Progetto chiuso

Data della firma CE 20 Giugno 2022

Data di avvio 1 Settembre 2023

Data di completamento 31 Agosto 2025

Finanziato da

• Marie Skłodowska-Curie Actions (MSCA)

Costo totale

Nessun dato

Contributo UE

€ 189 687,36

Coordinato da

JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (1)

Communication, Dissemination & Outreach Plan

The plan describes the planned measures to maximize the impact ofthe project, including the dissemination and exploitation measures that are planned,and the target group(s) addressed. Regarding communication measures and publicengagement strategy, the aim is to inform and reach out to society and show theactivities performed, and the use and the benefits the project will have for citizens.

Data Management Plan (1)

Data Management Plan

The Data Management Plan describes the data management life cyclefor all data sets that will be collected, processed or generated by the action. It is adocument describing what data will be collected, processed or generated andfollowing what methodology and standards, whether and how this data will beshared and/or made open, and how it will be curated and preserved.

Pubblicazioni

Peer reviewed articles (5)

A novel Leishmania infantum reference strain for gene editing and the study of visceral leishmaniasis

Autori: Rokhaya Thiam, Maria Santana Ceballos, Tom Beneke, Nada Kuk, Grégoire Pasquier, Lucien Crobu, Daniel C. Jeffares, Baptiste Vergnes, Bridlin Barckmann, Yvon Sterkers
Pubblicato in: PLOS One, Numero 20, 2025, ISSN 1932-6203
Editore: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PONE.0327390

Evolutionary adaptations of doublet microtubules in trypanosomatid parasites

Autori: Matthew H. Doran, Qingwei Niu, Jianwei Zeng, Tom Beneke, James Smith, Peter Ren, Sophia Fochler, Adrian Coscia, Johanna L. Höög, Shimi Meleppattu, Polina V. Lishko, Richard J. Wheeler, Eva Gluenz, Rui Zhang, Alan Brown
Pubblicato in: Science, Numero 387, 2025, ISSN 0036-8075
Editore: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIENCE.ADR5507

Improved base editing and functional screening in Leishmania via co-expression of the AsCas12a ultra variant, a T7 RNA polymerase, and a cytosine base editor

Autori: Nicole Herrmann May, Anh Cao, Annika Schmid, Fabian Link, Jorge Arias-del-Angel, Elisabeth Meiser, Tom Beneke
Pubblicato in: eLife, Numero 13, 2025, ISSN 2050-084X
Editore: eLife Sciences Publications, Ltd
DOI: 10.7554/ELIFE.97437.3

TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen

Autori: Andreia Albuquerque-Wendt, Ciaran McCoy, Rachel Neish, Ulrich Dobramysl, Çağla Alagöz, Tom Beneke, Sally A. Cowley, Kathryn Crouch, Richard J. Wheeler, Jeremy C. Mottram, Eva Gluenz
Pubblicato in: Nature Communications, Numero 16, 2025, ISSN 2041-1723
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-55538-7

<i>Leishmania mexicana</i> pathogenicity requires flagellar assembly but not motility

Autori: Tom Beneke, Rachel Neish, Carolina M. C. Catta-Preta, James Smith, Jessica Valli, Ciaran J. McCoy, Andreia Albuquerque-Wendt, Jeremy C. Mottram, Eva Gluenz
Pubblicato in: Virulence, Numero 16, 2025, ISSN 2150-5594
Editore: Informa UK Limited
DOI: 10.1080/21505594.2025.2521478