Nonequilibrium thermodynamics of the origin of life

Project Information

NETOLife

Grant agreement ID: 101068029

DOI

10.3030/101068029

Project closed

EC signature date 15 June 2022

Start date 1 June 2023

End date 31 July 2026

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 181 152,96

Coordinated by

UNIVERSIDAD POMPEU FABRA
Spain

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan

The Data Management Plan describes the data management life cyclefor all data sets that will be collected, processed or generated by the action. It is adocument describing what data will be collected, processed or generated andfollowing what methodology and standards, whether and how this data will beshared and/or made open, and how it will be curated and preserved.

Documents, reports (1)

Communication, Dissemination & Outreach Plan

The plan describes the planned measures to maximize the impact ofthe project, including the dissemination and exploitation measures that are planned,and the target group(s) addressed. Regarding communication measures and publicengagement strategy, the aim is to inform and reach out to society and show theactivities performed, and the use and the benefits the project will have for citizens.

Publications

Peer reviewed articles (20)

Information bounds production in replicator systems

Author(s): Jordi Piñero, Damian R. Sowinski, Gourab Ghoshal, Adam Frank, Artemy Kolchinsky
Published in: Communications Physics, Issue 9, 2026, ISSN 2399-3650
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S42005-026-02527-5

Maximizing Free Energy Gain

Author(s): Artemy Kolchinsky, Iman Marvian, Can Gokler, Zi-Wen Liu, Peter Shor, Oles Shtanko, Kevin Thompson, David Wolpert, Seth Lloyd
Published in: Entropy, Issue 27, 2025, ISSN 1099-4300
Publisher: MDPI AG
DOI: 10.3390/E27010091

Inferring Entropy Production in Many-Body Systems Using Nonequilibrium Maximum Entropy

Author(s): Miguel Aguilera, Sosuke Ito, Artemy Kolchinsky
Published in: Physical Review Letters, Issue 136, 2026, ISSN 0031-9007
Publisher: American Physical Society (APS)
DOI: 10.1103/XGKJ-DXZH

Protocellular energy transduction, information and fitness

Author(s): Kristoffer Reinholt Thomsen, Artemy Kolchinsky, Steen Rasmussen
Published in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 380, 2026, ISSN 0962-8436
Publisher: The Royal Society
DOI: 10.1098/RSTB.2024.0294

Elementary derivation of the dissipation-coherence bound for stochastic oscillators

Author(s): Artemy Kolchinsky
Published in: Physical Review E, Issue 114, 2026, ISSN 2470-0045
Publisher: American Physical Society (APS)
DOI: 10.1103/YJ2T-FRGZ

Optimization of nonequilibrium free energy harvesting illustrated on bacteriorhodopsin

Author(s): Jordi Piñero, Ricard Solé, Artemy Kolchinsky
Published in: Physical Review Research, Issue 6, 2024, ISSN 2643-1564
Publisher: American Physical Society (APS)
DOI: 10.1103/PHYSREVRESEARCH.6.013275

Optimization of nonequilibrium free energy harvesting illustrated on bacteriorhodopsin

Author(s): Jordi Piñero; Ricard Solé; Artemy Kolchinsky
Published in: Physical Review Research, 2024, ISSN 2643-1564
Publisher: APS
DOI: 10.1103/PHYSREVRESEARCH.6.013275

Thermodynamic bound on spectral perturbations, with applications to oscillations and relaxation dynamics

Author(s): Artemy Kolchinsky, Naruo Ohga, Sosuke Ito
Published in: Physical Review Research, Issue 6, 2024, ISSN 2643-1564
Publisher: American Physical Society (APS)
DOI: 10.1103/PHYSREVRESEARCH.6.013082

Thermodynamic Geometric Constraint on the Spectrum of Markov Rate Matrices

Author(s): Guo-Hua Xu, Artemy Kolchinsky, Jean-Charles Delvenne, Sosuke Ito
Published in: Physical Review Letters, Issue 135, 2025, ISSN 0031-9007
Publisher: American Physical Society (APS)
DOI: 10.1103/Z4T2-18CX

What it takes to solve the origins of life: An integrated review. Part 2: Theoretical methods and emerging trends

Author(s): Silke Asche, Carla Bautista, Celia Blanco, David Boulesteix, Alexandre Champagne-Ruel, Cole Mathis, Omer Markovitch, Zhen Peng, Avinash Vicholous Dass, Alyssa Adams, Eloi Camprubi, Enrico Sandro Colizzi, Stephanie Colón-Santos, Hannah Dromiack, Valentina Erastova, Amanda Garcia, Ghjuvan Grimaud, Aaron Halpern, Stuart A. Harrison, Seán F. Jordan, Tony Z. Jia, Amit Kahana, Artemy Kolchinsky, Odin Moron-Garcia, Ryo Mizuuchi, Jingbo Nan, Yuliia Orlova, Ben K.D. Pearce, Klaus Paschek, Martina Preiner, Silvana Pinna, Eduardo Rodríguez-Román, Loraine Schwander, Siddhant Sharma, Harrison B. Smith, Andrey Vieira, Joana C. Xavier
Published in: Cell Reports Physical Science, Issue 7, 2026, ISSN 2666-3864
Publisher: Elsevier BV
DOI: 10.1016/J.XCRP.2026.103211

Thermodynamics of Darwinian selection in molecular replicators

Author(s): Artemy Kolchinsky
Published in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 380, 2026, ISSN 0962-8436
Publisher: The Royal Society
DOI: 10.1098/RSTB.2024.0436

Neutral theory of cooperative dynamics

Author(s): Jordi Piñero, Artemy Kolchinsky, Sidney Redner, Ricard Solé
Published in: Proceedings of the National Academy of Sciences, Issue 122, 2025, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/PNAS.2515423122

Fundamental constraints to the logic of living systems

Author(s): Ricard Solé, Christopher P. Kempes, Bernat Corominas-Murtra, Manlio De Domenico, Artemy Kolchinsky, Michael Lachmann, Eric Libby, Serguei Saavedra, Eric Smith, David Wolpert
Published in: Interface Focus, Issue 14, 2024, ISSN 2042-8898
Publisher: The Royal Society
DOI: 10.1098/RSFS.2024.0010

Partial Information Decomposition: Redundancy as Information Bottleneck

Author(s): Artemy Kolchinsky
Published in: Entropy, Issue 26, 2025, ISSN 1099-4300
Publisher: MDPI AG
DOI: 10.3390/E26070546

Physics of Life: Exploring Information as a Distinctive Feature of Living Systems

Author(s): Stuart Bartlett, Andrew W. Eckford, Matthew Egbert, Manasvi Lingam, Artemy Kolchinsky, Adam Frank, Gourab Ghoshal
Published in: PRX Life, Issue 3, 2025, ISSN 2835-8279
Publisher: American Physical Society (APS)
DOI: 10.1103/RSX4-8X5F

Generalized free energy and excess/housekeeping decomposition in nonequilibrium systems: From large deviations to thermodynamic speed limits

Author(s): Artemy Kolchinsky, Andreas Dechant, Kohei Yoshimura, Sosuke Ito
Published in: Physical Review Research, Issue 8, 2026, ISSN 2643-1564
Publisher: American Physical Society (APS)
DOI: 10.1103/R48T-DGHL

What it takes to solve the origin of life: An integrated review. Part 1–Experimental methods and data repositories

Author(s): Silke Asche, Carla Bautista, Celia Blanco, David Boulesteix, Alexandre Champagne-Ruel, Cole Mathis, Omer Markovitch, Zhen Peng, Avinash Vicholous Dass, Alyssa Adams, Eloi Camprubi, Enrico Sandro Colizzi, Stephanie Colón-Santos, Hannah Dromiack, Valentina Erastova, Amanda Garcia, Ghjuvan Grimaud, Aaron Halpern, Stuart A. Harrison, Seán F. Jordan, Tony Z. Jia, Amit Kahana, Artemy Kolchinsky, Odin Moron-Garcia, Ryo Mizuuchi, Jingbo Nan, Yuliia Orlova, Ben K.D. Pearce, Klaus Paschek, Martina Preiner, Silvana Pinna, Eduardo Rodríguez-Román, Loraine Schwander, Siddhant Sharma, Harrison B. Smith, Andrey Vieira, Joana C. Xavier
Published in: Cell Reports Physical Science, Issue 7, 2026, ISSN 2666-3864
Publisher: Elsevier BV
DOI: 10.1016/J.XCRP.2026.103212

Thermodynamic dissipation does not bound replicator growth and decay rates

Author(s): Artemy Kolchinsky
Published in: The Journal of Chemical Physics, Issue 161, 2024, ISSN 0021-9606
Publisher: AIP Publishing
DOI: 10.1063/5.0213466

Geometric thermodynamics of reaction-diffusion systems: Thermodynamic trade-off relations and optimal transport for pattern formation

Author(s): Ryuna Nagayama, Kohei Yoshimura, Artemy Kolchinsky, Sosuke Ito
Published in: Physical Review Research, Issue 7, 2025, ISSN 2643-1564
Publisher: American Physical Society (APS)
DOI: 10.1103/PHYSREVRESEARCH.7.033011

Spatiotemporal Organization of Chemical Oscillators via Phase Separation

Author(s): Jonathan Bauermann, Giacomo Bartolucci, Artemy Kolchinsky
Published in: Physical Review Letters, Issue 136, 2026, ISSN 0031-9007
Publisher: American Physical Society (APS)
DOI: 10.1103/SHZ6-7FJ9