Project description
Regulatory insight into the mechanical properties of cells
Cells interact within their environment by generating and sustaining mechanical forces. The mechanical properties of cells influence a plethora of cellular functions, including adhesion, migration and polarisation. They are also central during development and differentiation. However, the underlying regulatory networks responsible for controlling the mechanical properties of cells remain largely unexplored. Funded by the Marie Skłodowska-Curie Actions programme, the READ-seq project aims to address this by developing a microfluidic platform that combines physical and biochemical cell analysis. The platform will simultaneously measure the mechanical and morphological features of individual cells and associate them with their molecular profile, providing an unprecedented link between gene expression and cell mechanics.
Fields of science
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Funding Scheme
HORIZON-AG-UN - HORIZON Unit Grant
Coordinator
80539 Munchen
Germany
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