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CORDIS - Resultados de investigaciones de la UE
CORDIS

Supervised morphogenesis in gastruloids

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Update preprint with results Objective 1.2. + data repository imaging (figshare) & single-cell (GEO) data; submission for publication (se abrirá en una nueva ventana)

Successful identification of putative, targetable drivers of variation that can be precisely tuned to minimise variation (Task 1.2). Successful integration of molecular and phenotypic fingerprints. Update preprint with the results of Task 1.2. + data repository imaging (figshare) & single-cell (GEO) data; submission for publication. Link to updated preprint + data repository on SUMO website.

Community resource released as preprint + data repository (figshare) with results Objective 1.1. (se abrirá en una nueva ventana)

Catalogue of gastruloid morphotypes across the [genetic background x culture condition matrix] with a focus on heart and gut tube formation efficiency & morphodynamics. Community resource released as preprint + data repository (figshare) with results Objective 1.1. Links to community resources on SUMO website.

ELSA activities in RP1 (se abrirá en una nueva ventana)

Report on the activities outcomes and planned follow up to address ethical legal and social aspects ELSA These activities include engagement with strategic partners including the public and dissemination of best practices and guidelines when applicable with the ELMs field Any confidential information related to these activities will be included in the technical periodic report

Website and project logo (se abrirá en una nueva ventana)

Launch of SUMO website including project logo Including links to already available projectrelated data protocols computational frameworks Launch of the website will be coordinated with a press release via partner institutes and further promotion via social media of project partners Twitter Facebook ResearchGate LinkedIn

Contribution to the regulatory debate in RP1. (se abrirá en una nueva ventana)

Report on the activities outcomes and planned follow up to assess and address the ELMs portfolio needs This includes contribution to the regulatory debate by engaging early on and continuously with regulatory bodies Any confidential information related to these activities will be included in the technical periodic report

Portfolio’s Dissemination and communication activities RP1 (se abrirá en una nueva ventana)

Report in the form of a presentation andor written text which includes a description of the conducted activities their outcomes and planned followup events Prepared in collaboration with the Media Services and Outreach Facility of the MPICBG Dresden MPG The report will be shared on the SUMO Website

Contribution to the regulatory debate in RP2 (se abrirá en una nueva ventana)

Report on the activities, outcomes and planned follow up to assess and address the ELMs portfolio needs. This includes contribution to the regulatory debate by engaging early on and continuously with regulatory bodies. Any confidential information related to these activities will be included in the technical periodic report

Portfolio’s Dissemination and communication activities RP2 (se abrirá en una nueva ventana)

Report in the form of a presentation and/or written text, which includes a description of the conducted activities, their outcomes and planned follow-up events. Prepared in collaboration with the Media Services and Outreach Facility of the MPI-CBG (Dresden, MPG). The report will be shared on the SUMO Website.

ELSA activities in RP2. (se abrirá en una nueva ventana)

Report on the activities, outcomes and planned follow up to address ethical, legal and social aspects (ELSA). These activities include engagement with strategic partners (including the public), and dissemination of best practices and guidelines when applicable with the ELMs field. Any confidential information related to these activities will be included in the technical periodic report.

Publicaciones

Coordination between endoderm progression and gastruloid elongation controls endodermal morphotype choice (se abrirá en una nueva ventana)

Autores: 1. Farag N, Schiff C, Nachman I
Publicado en: Cold Spring Harbor Laboratory, 2023, ISSN 2692-8205
Editor: Developmental Cell/Cell Systems
DOI: 10.1101/2023.02.07.527329

Criteria for the standardization of stem-cell-based embryo models (se abrirá en una nueva ventana)

Autores: Alfonso Martinez Arias, Nicolas Rivron, Naomi Moris, Patrick Tam, Cantas Alev, Jianping Fu, Anna-Katerina Hadjantonakis, Jacob H. Hanna, Gabriella Minchiotti, Olivier Pourquie, Guojun Sheng, Liliana Solnica Krezel, Jesse V. Veenvliet, Aryeh Warmflash
Publicado en: Nature Cell Biology, Edición 26, 2024, ISSN 1465-7392
Editor: Springer Science and Business Media LLC
DOI: 10.1038/s41556-024-01492-x

Dynamic governance: A new era for consent for stem cell research (se abrirá en una nueva ventana)

Autores: Rosario Isasi, Heidi B. Bentzen, Morris Fabbri, Antonie Fuhr, Joel C. Glover, Nancy Mah, Deborah Mascalzoni, Sabine Mueller, Stefanie Seltmann, Andreas Kurtz
Publicado en: Stem Cell Reports, Edición 19, 2024, ISSN 2213-6711
Editor: Elsevier BV
DOI: 10.1016/j.stemcr.2024.07.006

Criteria for the standardization of stem-cell-based embryo models (se abrirá en una nueva ventana)

Autores: Alfonso Martinez Arias, Nicolas Rivron, Naomi Moris, Patrick Tam, Cantas Alev, Jianping Fu, Anna-Katerina Hadjantonakis, Jacob H. Hanna, Gabriella Minchiotti, Olivier Pourquie, Guojun Sheng, Liliana Solnica Krezel, Jesse V. Veenvliet & Aryeh Warmflash
Publicado en: Nature Cell Biology, 2024, ISSN 1465-7392
Editor: Springer Science and Business Media LLC
DOI: 10.1038/S41556-024-01492-X

Integrated molecular-phenotypic profiling reveals metabolic control of morphological variation in a stem-cell-based embryo model (se abrirá en una nueva ventana)

Autores: Alba Villaronga-Luque, Ryan G. Savill, Natalia López-Anguita, Adriano Bolondi, Sumit Garai, Seher Ipek Gassaloglu, Roua Rouatbi, Kathrin Schmeisser, Aayush Poddar, Lisa Bauer, Tiago Alves, Sofia Traikov, Jonathan Rodenfels, Triantafyllos Chavakis, Aydan Bulut-Karslioglu, Jesse V. Veenvliet
Publicado en: Cell Stem Cell, Edición 32, 2025, ISSN 1934-5909
Editor: Elsevier BV
DOI: 10.1016/J.STEM.2025.03.012

Public Preferences for Digital Health Data Sharing: Discrete Choice Experiment Study in 12 European Countries (se abrirá en una nueva ventana)

Autores: Roberta Biasiotto, Jennifer Viberg Johansson, Melaku Birhanu Alemu, Virginia Romano, Heidi Beate Bentzen, Jane Kaye, Mirko Ancillotti, Johanna Maria Catharina Blom, Gauthier Chassang, Dara Hallinan, Guðbjörg Andrea Jónsdóttir, Aníbal Monasterio Astobiza, Emmanuelle Rial-Sebbag, David Rodríguez-Arias, Nisha Shah, Lea Skovgaard, Ciara Staunton, Katharina Tschigg, Jorien Veldwijk, Deborah Mascalzoni
Publicado en: Journal of Medical Internet Research, Edición 25, 2023, ISSN 1438-8871
Editor: JMIR Publications Inc.
DOI: 10.2196/47066

Gastruloid optimization. (se abrirá en una nueva ventana)

Autores: Lara Avni 1, Naama Farag , Binita Ghosh , Iftach Nachman
Publicado en: Emerg Top Life Sci ., 2023, ISSN 2397-8554
Editor: Portland Press
DOI: 10.1042/ETLS20230096

Public Preferences for Digital Health Data Sharing: Discrete Choice Experiment Study in 12 European Countries (se abrirá en una nueva ventana)

Autores: Roberta Biasiotto, Jennifer Viberg Johansson, Melaku Birhanu Alemu, Virginia Romano, Heidi Beate Bentzen, Jane Kaye, Mirko Ancillotti, Johanna Maria Catharina Blom, Gauthier Chassang, Dara Hallinan, Gubjrg Andrea Jnsdttir, Anbal Monasterio Astobiza, Emmanuelle Rial-Sebbag, David Rodrguez-Arias, Nisha Shah, Lea Skovgaard, Ciara Staunton, Katharina Tschigg, Jorien Veldwijk, Deborah Mascalzoni
Publicado en: Journal of Medical Internet Research, Edición 25, 2023, ISSN 1438-8871
Editor: JMIR Publications Inc.
DOI: 10.2196/47066

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