NEurological MEchanismS of Injury, and Sleep-like cellular dynamics

Información del proyecto

NEMESIS

Identificador del acuerdo de subvención: 101071900

DOI

10.3030/101071900

Fecha de la firma de la CE 28 Febrero 2023

Fecha de inicio 1 Octubre 2023

Fecha de finalización 30 Septiembre 2029

Financiado con arreglo a

• European Research Council (ERC)

Coste total

€ 9 927 253,75

Aportación de la UE

€ 9 927 253,75

Coordinado por

UNIVERSITA DEGLI STUDI DI PADOVA
Italy

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (39)

Fluctuation-dissipation theorem and the discovery of distinctive off-equilibrium signatures of brain states

Autores: Juan Manuel Monti, Yonatan Sanz Perl, Enzo Tagliazucchi, Morten L. Kringelbach, Gustavo Deco
Publicado en: Physical Review Research, Edición 7, 2025, ISSN 2643-1564
Editor: American Physical Society (APS)
DOI: 10.1103/PHYSREVRESEARCH.7.013301

Oral Sessions

Publicado en: Journal of Sleep Research, Edición 33, 2024, ISSN 0962-1105
Editor: Wiley
DOI: 10.1111/JSR.14290

Thalamic feedback shapes brain responses evoked by cortical stimulation in mice and humans

Autores: Simone Russo, Leslie D. Claar, Giulia Furregoni, Lydia C. Marks, Giri Krishnan, Flavia Maria Zauli, Gabriel Hassan, Michela Solbiati, Piergiorgio d’Orio, Ezequiel Mikulan, Simone Sarasso, Mario Rosanova, Ivana Sartori, Maxim Bazhenov, Andrea Pigorini, Marcello Massimini, Christof Koch, Irene Rembado
Publicado en: Nature Communications, Edición 16, 2025, ISSN 2041-1723
Editor: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-58717-2

Complex harmonics reveal low-dimensional manifolds of critical brain dynamics

Autores: Gustavo Deco, Yonatan Sanz Perl, Morten L. Kringelbach
Publicado en: Physical Review E, Edición 111, 2025, ISSN 2470-0045
Editor: American Physical Society (APS)
DOI: 10.1103/PHYSREVE.111.014410

An integrative, multiscale view on neural theories of consciousness

Autores: Johan F. Storm, P. Christiaan Klink, Jaan Aru, Walter Senn, Rainer Goebel, Andrea Pigorini, Pietro Avanzini, Wim Vanduffel, Pieter R. Roelfsema, Marcello Massimini, Matthew E. Larkum, Cyriel M.A. Pennartz
Publicado en: Neuron, Edición 112, 2025, ISSN 0896-6273
Editor: Elsevier BV
DOI: 10.1016/J.NEURON.2024.02.004

The Thermodynamics of Mind

Autores: Morten L. Kringelbach, Yonatan Sanz Perl, Gustavo Deco
Publicado en: Trends in Cognitive Sciences, Edición 28, 2024, ISSN 1364-6613
Editor: Elsevier BV
DOI: 10.1016/J.TICS.2024.03.009

Complex harmonics reveal low-dimensional manifolds of critical brain dynamics

Autores: Gustavo Deco, Yonatan Sanz Perl, Morten L. Kringelbach
Publicado en: Physical Review E, Edición 111, 2025, ISSN 2470-0045
Editor: American Physical Society (APS)
DOI: 10.1103/PHYSREVE.111.014410

Whole-brain turbulent dynamics predict responsiveness to pharmacological treatment in major depressive disorder

Autores: Escrichs, A; Sanz Perl, Y; Fisher, PM; Martínez-Molina, N; G-Guzman, E; Frokjaer, VG; Kringelbach, ML; Knudsen, GM; Deco, G
Publicado en: Molecular Psychiatry, 2024, ISSN 1476-5578
Editor: Springer
DOI: 10.1038/S41380-024-02690-7

Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation

Autores: Paulina Clara Dagnino; Anira Escrichs; Ane López-González; Olivia Gosseries; Jitka Annen; Yonatan Sanz Perl; Morten L. Kringelbach; Steven Laureys; Gustavo Deco
Publicado en: PLOS Computational Biology, 2023, ISSN 1553-7358
Editor: San Francisco, CA Public Library of Science
DOI: 10.1101/2023.07.17.549269

Functional hierarchies in brain dynamics characterized by signal reversibility in ferret cortex

Autores: Sebastián Idesis; Sebastián Geli; Joshua Faskowitz; Jakub Vohryzek; Yonatan Sanz Perl; Florian Pieper; Edgar Galindo‐Leon; Andreas K. Engel; Gustavo Deco
Publicado en: PLOS Computational Biology, 2023, ISSN 1553-7358
Editor: San Francisco CA: Public Library of Science
DOI: 10.1371/JOURNAL.PCBI.1011818

Network Desynchronization with Sine Waves: from Synchrony to Asynchrony by Periodic Stimulation

Autores: Joana Covelo, Martina Cortada, Gianni V. Vinci, Maurizio Mattia, Maria V. Sanchez‐Vives
Publicado en: Advanced Science, Edición 12, 2025, ISSN 2198-3844
Editor: Wiley Advanced Science
DOI: 10.1002/ADVS.202414602

H‐current modulation of cortical Up and Down states

Autores: Leonardo Dalla Porta, Almudena Barbero‐Castillo, José Manuel Sanchez‐Sanchez, Nathalia Cancino, Maria V. Sanchez‐Vives
Publicado en: The Journal of Physiology, Edición 603, 2025, ISSN 0022-3751
Editor: Wiley
DOI: 10.1101/2024.04.05.588281V1

Sleep-like cortical dynamics during wakefulness and their network effects following brain injury

Autores: Marcello Massimini, Maurizio Corbetta, Maria V. Sanchez-Vives, Thomas Andrillon, Gustavo Deco, Mario Rosanova, Simone Sarasso
Publicado en: Nature Communications, Edición 15, 2024, ISSN 2041-1723
Editor: Springer Science and Business Media LLC
DOI: 10.1038/S41467-024-51586-1

Different hierarchical reconfigurations in the brain by psilocybin and escitalopram for depression

Autores: Deco, G; Sanz Perl, Y; Johnson, S; Bourke, N; Carhart-Harris, RL; Kringelbach, ML
Publicado en: Nature Mental Health, 2024, ISSN 2731-6076
Editor: Springer
DOI: 10.1038/S44220-024-00298-Y

Human brain dynamics are shaped by rare long-range connections over and above cortical geometry

Autores: Jakub Vohryzek, Yonatan Sanz-Perl, Morten L. Kringelbach, Gustavo Deco
Publicado en: Proceedings of the National Academy of Sciences, Edición 122, 2025, ISSN 0027-8424
Editor: Proceedings of the National Academy of Sciences
DOI: 10.1073/PNAS.2415102122

Whole-brain model replicates sleep-like slow-wave dynamics generated by stroke lesions

Autores: Sebastian Idesis, Gustavo Patow, Michele Allegra, Jakub Vohryzek, Yonatan Sanz Perl, Maria V. Sanchez-Vives, Marcello Massimini, Maurizio Corbetta, Gustavo Deco
Publicado en: Neurobiology of Disease, Edición 200, 2024, ISSN 0969-9961
Editor: Elsevier BV
DOI: 10.1016/J.NBD.2024.106613

Non-local Schrödinger diffusion model reveals mechanisms of critical brain dynamics

Autores: Gustavo Deco, Yonatan Sanz Perl, Morten L. Kringelbach
Publicado en: Cell Reports Physical Science, Edición 6, 2025, ISSN 2666-3864
Editor: Elsevier BV
DOI: 10.1016/J.XCRP.2025.102663

Transcranial magnetic vs intracranial electric stimulation: a direct comparison of their effects via scalp EEG recordings

Autores: Renzo Comolatti, Gabriel Hassan, Ezequiel Mikulan, Simone Russo, Michele A. Colombo, Elisabetta Litterio, Giulia Furregoni, Sasha D'Ambrosio, Matteo Fecchio, Sara Parmigiani, Ivana Sartori, Silvia Casarotto, Andrea Pigorini, Marcello Massimini
Publicado en: Brain Stimulation, Edición 18, 2025, ISSN 1935-861X
Editor: Elsevier BV
DOI: 10.1016/J.BRS.2025.07.016

European Journal of Neuroscience

Autores: Rutiku, Renate; Fiscone, Chiara; Massimini, Marcello; Sarasso, Simone
Publicado en: European Journal of Neuroscience, 2024, ISSN 0953-816X
Editor: Wiley
DOI: 10.1111/EJN.16302

Are disorders of consciousness ‘dis’connection or ‘dys’connection syndromes?

Autores: Brian L Edlow, Marcello Massimini
Publicado en: Brain Communications, Edición 5, 2023, ISSN 2632-1297
Editor: Oxford University Press (OUP)
DOI: 10.1093/BRAINCOMMS/FCAD328

Non-equilibrium whole-brain dynamics arise from pairwise interactions

Autores: Sebastian M. Geli, Christopher W. Lynn, Morten L. Kringelbach, Gustavo Deco, Yonatan Sanz Perl
Publicado en: Cell Reports Physical Science, Edición 6, 2025, ISSN 2666-3864
Editor: Elsevier BV
DOI: 10.1016/J.XCRP.2025.102464

Riemannian Geometry for the Classification of Brain States with Intracortical Brain Recordings

Autores: Arnau Marin‐Llobet, Sergio Sánchez‐Manso, Arnau Manasanch, Lluc Tresserras, Xinhe Zhang, Yining Hua, Hao Zhao, Melody Torao‐Angosto, Maria V Sanchez‐Vives, Leonardo Dalla Porta
Publicado en: Advanced Intelligent Systems, 2025, ISSN 2640-4567
Editor: Wiley
DOI: 10.1002/AISY.202500480

Localizing hidden Interictal Epileptiform Discharges with simultaneous intracerebral and scalp high-density EEG recordings

Autores: Flavia Maria Zauli, Maria Del Vecchio, Andrea Pigorini, Simone Russo, Marcello Massimini, Ivana Sartori, Francesco Cardinale, Piergiorgio d’Orio, Ezequiel Mikulan
Publicado en: Journal of Neuroscience Methods, Edición 409, 2024, ISSN 0165-0270
Editor: Elsevier BV
DOI: 10.1016/J.JNEUMETH.2024.110193

Poster sessions–late breaking abstracts

Publicado en: Journal of Sleep Research, Edición 33, 2024, ISSN 0962-1105
Editor: Wiley
DOI: 10.1111/JSR.14293

Spatiotemporal network dynamics and structural correlates in the human cerebral cortex in vitro

Autores: Joana Covelo, Alessandra Camassa, Jose Manuel Sanchez-Sanchez, Arnau Manasanch, Leonardo Dalla Porta, Nathalia Cancino-Fuentes, Almudena Barbero-Castillo, Rita M. Robles, Miquel Bosch, Silvia Tapia-Gonzalez, Paula Merino-Serrais, Mar Carreño, Estefania Conde-Blanco, Jordi Rumià Arboix, Pedro Roldán, Javier DeFelipe, Maria V. Sanchez-Vives
Publicado en: Progress in Neurobiology, Edición 246, 2025, ISSN 0301-0082
Editor: Elsevier BV
DOI: 10.1016/J.PNEUROBIO.2025.102719

Modelling low-dimensional interacting brain networks reveals organising principle in human cognition

Autores: Yonatan Sanz Perl, Sebastian Geli, Eider Pérez-Ordoyo, Lou Zonca, Sebastian Idesis, Jakub Vohryzek, Viktor K. Jirsa, Morten L. Kringelbach, Enzo Tagliazucchi, Gustavo Deco
Publicado en: Network Neuroscience, 2025, ISSN 2472-1751
Editor: MIT Press
DOI: 10.1162/NETN_A_00434

Frontiers in Neuroinformatics

Autores: Noelia Martínez-Molina; Yonatan Sanz-Perl; Anira Escrichs; Morten L. Kringelbach; Morten L. Kringelbach; Morten L. Kringelbach; Gustavo Deco; Gustavo Deco
Publicado en: Frontiers in Neuroinformatics, 2024, ISSN 1662-5196
Editor: Lausanne: Frontiers Media S.A
DOI: 10.3389/FNINF.2024.1382372

Covert consciousness: what’s in a name?

Autores: Charlène Aubinet, Jan Claassen, Brian L Edlow, David Fischer, Olivia Gosseries, Christof Koch, Daniel Kondziella, Marcello Massimini, Michael J Young
Publicado en: Brain, 2025, ISSN 0006-8950
Editor: Oxford University Press (OUP)
DOI: 10.1093/BRAIN/AWAF349

Conscious tactile perception entails distinct neural dynamics within somatosensory areas

Autores: Davide Albertini, Maria Del Vecchio, Ivana Sartori, Andrea Pigorini, Francesca Talami, Flavia Maria Zauli, Simone Sarasso, Ezequiel Pablo Mikulan, Marcello Massimini, Pietro Avanzini
Publicado en: Current Biology, Edición 35, 2025, ISSN 0960-9822
Editor: Elsevier BV
DOI: 10.1016/J.CUB.2025.04.052

Scientific Reports

Autores: Adrián Ponce-Alvarez; Gustavo Deco
Publicado en: The Hopf whole-brain model and its linear approximation, 2023, ISSN 2045-2322
Editor: Springer
DOI: 10.21203/RS.3.RS-3361733/V1

Whole brain modelling for simulating pharmacological interventions on patients with disorders of consciousness

Autores: Mindlin, I; Herzog, R; Belloli, L; Manasova, D; Monge-Asensio, M; Vohryzek, J; Escrichs, A; Alnagger, N; Núñez, P; Gosseries, O; Kringelbach, ML; Deco, G; Tagliazucchi, E; Naccache, L; Rohaut, B; Sitt, JD; Sanz Perl, Y
Publicado en: Communications Biology, 2024, ISSN 2399-3642
Editor: Springer
DOI: 10.1038/S42003-024-06852-9

Whole-brain model replicates sleep-like slow-wave dynamics generated by stroke lesions

Autores: Sebastian Idesis, Gustavo Patow, Michele Allegra, Jakub Vohryzek, Yonatan Sanz Perl, Maria V. Sanchez-Vives, Marcello Massimini, Maurizio Corbetta, Gustavo Deco
Publicado en: Neurobiology of Disease, Edición 200, 2024, ISSN 0969-9961
Editor: Elsevier BV
DOI: 10.1016/J.NBD.2024.106613

Investigating the Impact of Local Manipulations on Spontaneous and Evoked Brain Complexity Indices: A Large-Scale Computational Model

Autores: Gianluca Gaglioti, Thierry Ralph Nieus, Marcello Massimini, Simone Sarasso
Publicado en: Applied Sciences, Edición 14, 2025, ISSN 2076-3417
Editor: MDPI AG
DOI: 10.3390/APP14020890

Scientific Reports

Autores: Idesis, Sebastian; Allegra, Michele; Vohryzek, Jakub; Sanz Perl, Yonatan; Faskowitz, Joshua; Sporns, Olaf; Corbetta, Maurizio; Deco, Gustavo
Publicado en: A low dimensional embedding of brain dynamics enhances diagnostic accuracy and behavioral prediction in stroke, 2023, ISSN 2045-2322
Editor: Springer
DOI: 10.1038/S41598-023-42533-Z

Reduction of sleep-like perilesional slow waves and clinical evolution after stroke: A TMS-EEG study

Autores: S. Sarasso, S. D’Ambrosio, S. Russo, L. Bernardelli, G. Hassan, A. Comanducci, P. De Giampaulis, L.A. Dalla Vecchia, J. Lanzone, M. Massimini
Publicado en: Clinical Neurophysiology, Edición 175, 2025, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/J.CLINPH.2025.2110746

Detecting cortical reactivity alterations induced by structural disconnection in subcortical stroke

Autores: Sasha D'Ambrosio, Francesco Certo, Letizia Bernardelli, Lorenzo Pini, Maurizio Corbetta, Leonardo Pantoni, Marcello Massimini, Simone Sarasso
Publicado en: Clinical Neurophysiology, Edición 156, 2024, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/J.CLINPH.2023.09.007

Whole-brain dynamics across the menstrual cycle: the role of hormonal fluctuations and age in healthy women

Autores: Daniela S. Avila-Varela; Esmeralda Hidalgo-Lopez; Paulina Clara Dagnino; Irene Acero-Pousa; Elvira del Agua; Gustavo Deco; Belinda Pletzer; Anira Escrichs
Publicado en: npj Women's Health, 2024, ISSN 2948-1716
Editor: Springer
DOI: 10.1038/S44294-024-00012-4

Whole-brain modelling: an essential tool for understanding brain dynamics

Autores: Gustavo Patow; Ignacio Martin; Yonatan Sanz Perl; Morten L. Kringelbach; Gustavo Deco
Publicado en: Nature Reviews Methods Primers, 2024, ISSN 2662-8449
Editor: Springer
DOI: 10.1038/S43586-024-00336-0

European Journal of Neuroscience

Autores: Casarotto, Silvia; Hassan, Gabriel; Rosanova, Mario; Sarasso, Simone; Derchi, Chiara-Camilla; Trimarchi, Pietro Davide; Viganò, Alessandro; Russo, Simone; Fecchio, Matteo; Devalle, Guya; Navarro, Jorge; Massimini, Marcello; Comanducci, Angela
Publicado en: European Journal of Neuroscience, 2024, ISSN 0953-816X
Editor: Blackwell Publishing Inc.
DOI: 10.1111/EJN.16299

Other (1)

Generative whole-brain dynamics models from healthy subjects predict functional alterations in stroke at the level of individual patients

Autores: Sebastián Idesis; Michele Allegra; Jakub Vohryzek; Yonatan Sanz Perl; Nicholas V. Metcalf; Joseph C. Griffis; Maurizio Corbetta; Gordon L. Shulman; Gustavo Deco
Publicado en: Brain Communications, 2024
DOI: 10.1093/BRAINCOMMS/FCAE237