FuEl ThE bRaiN In healtThY aging and agE-relateD diseases

Project Information

ETERNITY

Grant agreement ID: 101072759

DOI

10.3030/101072759

EC signature date 6 July 2022

Start date 1 February 2023

End date 31 January 2027

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 2 629 260,00

Coordinated by

UNIVERSITA DEGLI STUDI DI MILANO
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (1)

Creation of ETERNITY website.

Publications

Peer reviewed articles (10)

Targeting senescent cells with NKG2D-CAR T cells

Author(s): Yushuang Deng, Avadh Kumar, Kan Xie, Kristina Schaaf, Enzo Scifo, Sarah Morsy, Tao Li, Armin Ehninger, Daniele Bano and Dan Ehninger
Published in: Cell Death Discovery, ISSN 2058-7716
Publisher: Springer Nature
DOI: 10.1038/S41420-024-01976-7

A lactate-dependent shift of glycolysis mediates synaptic and cognitive processes in male mice

Author(s): Ignacio Fernández-Moncada; Gianluca Lavanco; Unai B. Fundazuri; Nasrin Bollmohr; Sarah Mountadem; Tommaso Dalla Tor; Pauline Hachaguer; Francisca Julio-Kalajzic; Doriane Gisquet; Roman Serrat; Luigi Bellocchio; Astrid Cannich; Bérénice Fortunato-Marsol; Yusuke Nasu; Robert E. Campbell; Filippo Drago; Carla Cannizzaro; Guillaume Ferreira; Anne-Karine Bouzier-Sore; Luc Pellerin; Juan P. Bolaños; Gilles Bonvento; L. Felipe Barros; Stephane H. R. Oliet; Aude Panatier; Giovanni Marsicano
Published in: Nature Communications, 2024, ISSN 1476-4687
Publisher: Springer Nature
DOI: 10.1038/s41467-024-51008-2

Glucose-derived glutamate drives neuronal terminal differentiation in vitro

Author(s): D'Andrea, Laura; Audano, Matteo; Pedretti, Silvia; Pelucchi, Silvia; Stringhi, Ramona; Imperato, Gabriele; De Cesare, Giulia; Cambria, Clara; Laporte, Marine H; Zamboni, Nicola; Antonucci, Flavia; Di Luca, Monica; Mitro, Nico; Marcello, Elena
Published in: EMBO Reports, 2024
Publisher: PUBMED
DOI: 10.1038/S44319-023-00048-8

Analysis of the senescence‐associated cell surfaceome reveals potential senotherapeutic targets

Author(s): Yushuang Deng, Ting Liu, Enzo Scifo, Tao Li, Kan Xie, Bernd Taschler, Sarah Morsy, Kristina Schaaf, Armin Ehninger, Daniele Bano, Dan Ehninger
Published in: Aging Cell, 2024, ISSN 1474-9718
Publisher: Wiley
DOI: 10.1111/acel.14312

Rethinking the role of microglia in obesity

Author(s): Giulia Cutugno, Evangelia Kyriakidou, Agnes Nadjar
Published in: Neuropharmacology, ISSN 1873-7064
Publisher: Elsevier Ltd.
DOI: 10.1016/J.NEUROPHARM.2024.109951

Single cell whole-genome sequencing of brain cells: age- and cell-type specific mutational profiles

Author(s): Melania Capasso; N. Ahmad Aziz
Published in: Signal Transduction and Targeted Therapy, 2024, ISSN 1476-4687
Publisher: Springer Nature
DOI: 10.1038/s41392-024-01892-3

Potent, selective and reversible hMAO-B inhibition by benzalphthalides: Synthesis, enzymatic and cellular evaluations and virtual docking and predictive studies

Author(s): Esther del Olmo; Bianca Barboza; Maria Delgado-Esteban; Nerea Escala; Daniel Jiménez-Blasco; José L. Lopez-Pérez; Laura Cillero de la Fuente; Elías Quezada; Javier Munín; Dolores Viña; Juan P. Bolaños; Arturo San Feliciano
Published in: Bioorganic Chemistry, 2024
Publisher: ELSEVIER
DOI: 10.1016/J.BIOORG.2024.107255

Mitochondrial complex I inhibition enhances astrocyte responsiveness to pro-inflammatory stimuli

Author(s): Wischhof, Lena; John Mathew, Amal; Bonaguro, Lorenzo; Beyer, Marc; Ehninger, Dan; Nicotera, Pierluigi; Bano, Daniele
Published in: Scientific Reports, 2024
Publisher: NATURE
DOI: 10.1038/S41598-024-78434-Y

Weak neuronal glycolysis sustains cognition and organismal fitness

Author(s): D Jimenez-Blasco, J Agulla, R Lapresa, M Garcia-Macia, V Bobo-Jimenez, D Garcia-Rodriguez, I Manjarres-Raza, E Fernandez, Y Jeanson, S Khoury, JC Portais, D Padro, Ramos-Cabrer, P Carmeliet, A Almeida & JP Bolaños
Published in: Nature Metabolism, ISSN 2522-5812
Publisher: Springer Nature
DOI: 10.1038/S42255-024-01049-0

TET3 regulates terminal cell differentiation at the metabolic level

Author(s): Isabel Mulet; Carmen Grueso-Cortina; Mireia Cortés-Cano; Daniela Gerovska; Guangming Wu; Stefania Alexandra Iakab; Daniel Jimenez-Blasco; Andrea Curtabbi; Pablo Hernansanz-Agustín; Harmony Ketchum; Israel Manjarrés-Raza; F. Thomas Wunderlich; Juan Pedro Bolaños; Meelad M. Dawlaty; Carsten Hopf; José Antonio Enríquez; Marcos J. Araúzo-Bravo; Natalia Tapia
Published in: Nature Communications, 2024
Publisher: NATURE COMMUNICATIONS
DOI: 10.1038/S41467-024-54044-0