Project description DEENESFRITPL Computer-aided design system for breast cancer classification and prognosis of relapse Breast cancer (BC) incidence leads to more than 600 000 deaths annually. Distant metastasis due to illness relapse is incurable, underscoring the inadequacy of our understanding of its mechanisms. Thus, oncologists use screening programmes based on radiological and histopathological imaging to analyse tumours, study their immune microenvironment and predict the probability of distant metastasis and relapse. Funded by the Marie Skłodowska-Curie Actions programme, the BosomShield project proposes to join the two disciplines (pathological and radiological imaging) in a software that will analyse these images to classify cancer subtypes and predict distant metastasis and relapse. BosomShield will also provide high-level training to young researchers, advancing their skills and career prospects in BC research. Show the project objective Hide the project objective Objective Breast cancer (BC) incidence in women produces more than 600,000 deaths each year. The primary cause of death in BC patients is metastasis, whereby cancer cells spread from their primary site of origin and grow in adjacent or distant sites. Distant metastasis produced due to the relapse of the illness is incurable, underscoring the inadequacy of our understanding of its mechanisms. The first step for fighting against disease progression is screening programs for BC focused on image analysis of mammography, MRI and tomosynthesis. Once the tumour has been diagnosed and given the high variability of clinical progressions, another problem arises: classifying the cancer type and determining the proper treatment for specific cancer. Moreover, in BC, the immune response from the tumour microenvironment has played an essential role in tumour evolution. To evaluate the tumour and its microenvironment, one technique garnered a lot of attention in the last years: Whole Slide Imaging (WSI). This technique replaces the use of the microscope for classical diagnosis. Still, it has also been used for developing biomarkers that allow the analysis of tumours and classification of cancer subtypes and the study of the immune tumour microenvironment. The use of WSI has applications for predicting the probability of relapse for distant metastasis. Now, for the first time, BosomShield proposes to join the two disciplines (pathological and radiological imaging) in a software that will analyze these images to classify the cancer subtypes and predict (together with the complete clinical history of the patient) the probability of relapse for distant metastasis. Besides, BosomShield will provide high-level training in BC research to young researchers by offering the necessary transferable skills for thriving careers underpinned using diverse disciplines, digital radiology and pathology, biomedical, AI, privacy and software development. Fields of science medical and health sciencesclinical medicineradiologymedical and health sciencesclinical medicineoncologybreast cancermedical and health sciencesbasic medicinepathology Programme(s) HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme Topic(s) HORIZON-MSCA-2021-DN-01-01 - MSCA Doctoral Networks 2021 Call for proposal HORIZON-MSCA-2021-DN-01 See other projects for this call Funding Scheme HORIZON-AG-UN - HORIZON Unit Grant Coordinator UNIVERSITAT ROVIRA I VIRGILI Net EU contribution € 251 971,20 Address Carrer de escorxador 43003 Tarragona Spain See on map Region Este Cataluña Tarragona Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data Participants (9) Sort alphabetically Sort by Net EU contribution Expand all Collapse all KUNGLIGA TEKNISKA HOEGSKOLAN Sweden Net EU contribution € 293 709,60 Address Brinellvagen 8 100 44 Stockholm See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM Netherlands Net EU contribution € 274 370,40 Address Geert grooteplein 10 zuid 6525 GA Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data FUNDACIO INSTITUT D'INVESTIGACIO SANITARIA PERE VIRGILI (IISPV) Spain Net EU contribution € 251 971,20 Address Carrer escorxador 43003 Tarragona See on map Region Este Cataluña Tarragona Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data INSTYTUT BIOCYBERNETYKI I INZYNIERII BIOMEDYCZNEJ IM.MACIEJA NALECZA POLSKIEJ AKADEMII NAUK Poland Net EU contribution € 226 512,00 Address Ul. ksiecia trojdena 4 02 109 Warszawa See on map Region Makroregion województwo mazowieckie Warszawski stołeczny Miasto Warszawa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data UNIVERSITA DEGLI STUDI DI UDINE Italy Net EU contribution € 259 437,60 Address Via palladio 8 33100 Udine See on map Region Nord-Est Friuli-Venezia Giulia Udine Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE France Net EU contribution € 282 693,60 Address 32 avenue de l'observatoire 25000 Besancon See on map Region Bourgogne-Franche-Comté Franche-Comté Doubs Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data UNIVERZA V MARIBORU Slovenia Net EU contribution € 242 179,20 Address Slomskov trg 15 2000 Maribor See on map Region Slovenija Vzhodna Slovenija Podravska Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data N VISION SYSTEMS AND TECHNOLOGIES SL Spain Net EU contribution € 251 971,20 Address Avenida barcelona, 105, edificio ig-nova tecnoespa despacho 8 08700 Igualada See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Este Cataluña Barcelona Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data MEDIRI GMBH Germany Net EU contribution € 260 539,20 Address Eppelheimer str 13 69115 Heidelberg See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window EU contribution No data Partners (15) Sort alphabetically Sort by Net EU contribution Expand all Collapse all INSTITUTE OF TECHNOLOGY PETRONAS SDN BHD Malaysia Net EU contribution € 0,00 Address Universiti teknologi petronas bandar seri iskandar 31750 Bandar seri iskandar See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data The University of Texas Health Science Center at Houston United States Net EU contribution € 0,00 Address 7000 fannin, uct 1000 77030 Houston See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data UMMON HEALTHTECH France Net EU contribution € 0,00 Address 64e rue de sully 21000 Dijon See on map Region Bourgogne-Franche-Comté Bourgogne Côte-d’Or Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data O3 ENTERPRISE SRL Italy Net EU contribution € 0,00 Address Località padriciano n.99 34149 Trieste See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nord-Est Friuli-Venezia Giulia Trieste Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data SFERA IT STORITVE DOO Slovenia Net EU contribution € 0,00 Address Beloruska ulica 7 2000 Maribor See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Slovenija Vzhodna Slovenija Podravska Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data General Electric Company dba GE Research United States Net EU contribution € 0,00 Address 1 research circle 12309 Niskayuna See on map Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data HOCHSCHULE DARMSTADT (UNIVERSITY OF APPLIED SCIENCES H-DA) Germany Net EU contribution € 0,00 Address Schofferstrasse 3 64295 Darmstadt See on map Region Hessen Darmstadt Darmstadt, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data HOSPITAL UNIVERSITARI SANT JOAN DE REUS, SAM Spain Net EU contribution € 0,00 Address Av.dr.josep laporte, num 2 de reus 43204 Reus See on map Region Este Cataluña Tarragona Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data LUNDS UNIVERSITET Sweden Net EU contribution € 0,00 Address Paradisgatan 5c 22100 Lund See on map Region Södra Sverige Sydsverige Skåne län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data Univerzitetni klinicni center Maribor Slovenia Net EU contribution € 0,00 Address Ljubljanska ulica 5 2000 Maribor See on map Region Slovenija Vzhodna Slovenija Podravska Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data SERVICIO ANDALUZ DE SALUD Spain Net EU contribution € 0,00 Address Avenida de la constitucion 18 41071 Sevilla See on map Region Sur Andalucía Sevilla Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data AZIENDA SANITARIA UNIVERSITARIA FRIULI CENTRALE Italy Net EU contribution € 0,00 Address Via pozzuolo 330 33100 Udine See on map Region Nord-Est Friuli-Venezia Giulia Udine Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data UNIVERSITE DIJON BOURGOGNE France Net EU contribution € 0,00 Address Esplanade erasme maison de l universite 21078 Dijon cedex See on map Region Bourgogne-Franche-Comté Bourgogne Côte-d’Or Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data Hospital de Tortosa Verge de la Cinta Spain Net EU contribution € 0,00 Address C/ esplanetes 14 43500 Tortosa See on map Region Este Cataluña Tarragona Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data STICHTING RADBOUD UNIVERSITEIT Netherlands Net EU contribution € 0,00 Address Houtlaan 4 6525 XZ Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding No data