Training the next-generation of European GLIOblastoma (translational) researchers, to RESOLVE precision targeting of the brain tumour microenvironment

Project Information

GLIORESOLVE

Grant agreement ID: 101073386

DOI

10.3030/101073386

Project closed

EC signature date 6 July 2022

Start date 1 September 2022

End date 31 August 2026

Funded under

• Marie Skłodowska-Curie Actions (MSCA)

Total cost

No data

EU contribution

€ 2 672 925,60

Coordinated by

ROYAL COLLEGE OF SURGEONS IN IRELAND
Ireland

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (1)

Website, Twitter, Facebook Page

Website, Twitter, Facebook Page.

Other (1)

DR vacancies advertised

DR vacancies advertised.

Documents, reports (1)

Dissemination and public engagement reports 1

Dissemination & public engagement reports (events, talks, publications, posters, public engagement).

Publications

Peer reviewed articles (13)

Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors

Author(s): Biswas, Archita; Salvucci, Manuela; Connor, Kate; Dussmann, Heiko; Carberry, Steven; Fichtner, Michael; King, Ellen; Murphy, Brona; O'Farrell, Alice C.; Cryan, Jane; Beausang, Alan; Heffernan, Josephine; Cremona, Mattia; Hennessy, Bryan T.; Clerkin, James; Sweeney, Kieron J.; MacNally, Steve; Brett, Francesca; O'Halloran, Philip; Bacon, Orna; Furney, Simon; Verreault, Maite; Quissac, Emie; Bielle, Franck; Ahmed, Mohammed H.; Idbaih, Ahmed; Leenstra, Sieger; Ntafoulis, Ioannis; Fabro, Federica; Lamfers, Martine; Golebiewska, Anna; Hertel, Frank; Niclou, Simone P.; Yen, Romain Tching Chi; Kremer, Andreas; Dilcan, Gonca; Lodi, Francesca; Arijs, Ingrid; Lambrechts, Diether; Purushothama, Manasa Kalya; Kel, Alexander; Byrne, Annette T.; Prehn, Jochen H.M.
Published in: Journal of Neuro-Oncology, Issue 163, 2023
Publisher: Springer
DOI: 10.21203/RS.3.RS-2831912/V1

Building the blood-brain barrier: a scalable self-assembling 3D model of the brain microvasculature under unidirectional flow

Author(s): Jade Admiraal, Promise O. Emeh, Marleen Bokkers, Sander P. M. de Ruiter, Thomas Olivier, Karla Queiroz, Todd P. Burton, Nienke R. Wevers
Published in: Fluids and Barriers of the CNS, Issue 23, 2026, ISSN 2045-8118
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S12987-026-00765-X

Advanced 3D patient-derived glioblastoma organoid-immune cell co-cultures reveal preserved MHC-I tumor cell surface expression and tumor cell-driven T-cell dysfunction

Author(s): Mahsa Rezaeipour, Marta de Lucas Sanz, Hamed Allahverdi, Gaëlle Triballier, Eliane Klein, Ilaria Salvato, Pilar M. Moreno-Sanchez, Bakhtiyor Nosirov, Petr V. Nazarov, Batuhan Kisakol, Heiko Dussmann, Colum Connolly, Annette T. Byrne, Jochen H.M. Prehn, Dirk Brenner, Bassam Janji, Simone P. Niclou, Anna Golebiewska
Published in: Journal of Neuroinflammation, 2026, ISSN 1742-2094
Publisher: Springer Science and Business Media LLC
DOI: 10.1186/S12974-026-04048-Y

The ins and outs of microglial cells in brain health and disease

Author(s): Pallares-Moratalla, Carla; Bergers, Gabriele
Published in: Frontiers in Immunology, Issue 15, 2024, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/FIMMU.2024.1305087

Transcriptome fingerprinting of aberrant fibroblast activation unlocks effective therapeutics to tackle cardiac fibrosis

Author(s): Mathieu Cinato, Ryeonshi Kang, Solomiia Kramar, Lesia Savchenko, Nathalie Pizzinat, Audrey Swiader, Alexander Kel, Aleksandr Kalmykov, Daria Stelmashenko, Ilenia Martinelli, Jerome Roncalli, Charlotte Laborde, Oksana Kunduzova
Published in: Science Advances, Issue 11, 2025, ISSN 2375-2548
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIADV.ADX0968

The Pan-Tumor Vasculature under the Transcriptomic Magnifying Glass

Author(s): Krish Skandha Gopalan, Gabriele Bergers
Published in: Cancer Research, Issue 84, 2024, ISSN 0008-5472
Publisher: American Association for Cancer Research (AACR)
DOI: 10.1158/0008-5472.CAN-24-3219

OBSERVE: guidelines for the refinement of rodent cancer models

Author(s): Stéphanie I. De Vleeschauwer; Marieke van de Ven; Anaïs Oudin; Karlijn Debusschere; Kate Connor; Annette T. Byrne; Doreen Ram; Anne Marie Rhebergen; Yannick D. Raeves; Maik Dahlhoff; Virginie Dangles-Marie; Els R. Hermans
Published in: Nature Protocols, Issue 19, 2024, ISSN 1750-2799
Publisher: Springer Nature
DOI: 10.1038/s41596-024-00998-w

Modelling brain tumours with organoids: towards precision medicine in neuro-oncology

Author(s): Marta de Lucas Sanz, Simone P. Niclou, Anna Golebiewska
Published in: Nature Reviews Neurology, 2026, ISSN 1759-4758
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41582-026-01190-2

Immunosuppressive mechanisms and therapeutic interventions shaping glioblastoma immunity

Author(s): Pilar M. Moreno-Sanchez, Mahsa Rezaeipour, Else Marit Inderberg, Michael Platten, Anna Golebiewska
Published in: Nature Cancer, Issue 7, 2026, ISSN 2662-1347
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S43018-025-01097-9

Type I interferon drives T cell responses to amyloid beta in the central nervous system

Author(s): Julius J. Michel, Khwab Sanghvi, Jakob Rosenbauer, Lea Humbs, Clara Tejido Dierssen, Saskia Grudzenski-Theis, Viktoria Sachs, Kristine Jähne, Karoline Degenhardt, Lutz Frölich, Jochen Herms, Marc Fatar, Michael Platten, Lukas Bunse
Published in: Nature Communications, Issue 17, 2026, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-026-72262-6

Challenging the status quo to improve the translational potential of preclinical oncology studies

Author(s): Kate Connor; Anna Golebiewska; Annette T. Byrne
Published in: Nature Reviews Cancer, Issue 25, 2024, ISSN 1474-1768
Publisher: Nature Publishing
DOI: 10.1038/S41568-024-00756-W

Evaluating the NFPp10a/NF5310 glioblastoma model as a faithful avatar for screening tumour microenvironment–targeted therapies

Author(s): Kieron White, James Clerkin, Liam P. Shiels, Kieron Sweeney, Mohannad Dabbour, Alice C. O’Farrell, Maïté Verreault, Thomas Van Brussel, Ingrid Arijs, Suzanne Murphy, Evin M. Haworth, Christopher Van Hessche, Gautam Shankar, Joana Beyer, Patrick Dicker, Stephen G. Maher, Laure Marignol, Jack P. Gleeson, David O’Brien, Diether Lambrechts, Jochen H. M. Prehn, Ahmed Idbaih, Frederik De Smet, null null, Martine L. M. Lamfers, Sieger Leenstra, Ioannis Ntafoulis, Federica Fabro, Johan M. Kros, Franck Bielle, Emie Quissac, Francesca Lodi, Gonca Dilcan, Archita Biswas, Manuela Salvucci, Jane Cryan, Francesca Brett, Alan Beausang, Steve MacNally, Philip J. O’Halloran, Orna Bacon, Kate Connor, Annette T. Byrne
Published in: Communications Biology, 2026, ISSN 2399-3642
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S42003-026-10874-W

Distinct tumor immune microenvironmental landscapes drive divergent immunotherapy responses in glioblastoma

Author(s): Linqian Weng, Krish Skandha Gopalan, Mélanie Guyot, Maxime Vanmechelen, Pouya Nazari, Marie Duhamel, Clelia Donisi, Carla Pallarés-Moratalla, Abhishek D Garg, Kieron White, Annette T Byrne, Diether Lambrechts, Frederik De Smet, Gabriele Bergers
Published in: Neuro-Oncology, 2026, ISSN 1522-8517
Publisher: Oxford University Press (OUP)
DOI: 10.1093/NEUONC/NOAG018