CORDIS provides links to public deliverables and publications of HORIZON projects.
Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .
Deliverables
A detailed protocol on application of innovative technology IMC on tumor organoids will be created to uncover molecular changes at protein and single-cell level in tumor microenvironment after treatments. The protocol will be conducted by exchange of best practices and scientific knowledge within consortium. Protocol will be written, revised by partners of consortium, and available for consortium partners.
Guidelines - Reaching excellence in project management (opens in new window)The guidelines will be produced for internal and external use by interested members of the public, identifying best practices for specific phases of project management and developing them further in the form of recommendations and guidelines to achieve and maintain project management excellence.
Report on the research trainings and expert exchange (opens in new window)Reports on the research trainings and expert exchange conducted under WP5 will be consistent with Dissemination/twinning/networking activities of the project and will include explanations for any discrepancies. Reports shall include description of all activities within research trainings and expert visits including meetings between partner´ staff, exchange of know-how, hands-on training of researchers, summer schools and workshops.
Progress Report (opens in new window)The progress report as a deliverable at Month 17, will be the basis for the interim review meeting.
A protocol for application of ISS on tumour organoids (opens in new window)A detailed protocol on application of state-of-the art methodology ISS on tumor organoids will be created to uncover molecular changes at gene level in tumor microenvironment after treatments. The protocol will be conducted by exchange of best practices and scientific knowledge within consortium. Protocol will be written, revised by partners of consortium, and available for consortium partners.
Scientific publications (opens in new window)Peer-reviewed scientific publications: Dissemination of project results to the international scientific community will be accomplished through publication of results (2-4 papers ) in high impact scientific journals in the scope of Toxicology, Cancer Research, Oncology, etc. Unless there are specific reasons not to do so, only the Open Access format will be chosen, allowing unrestricted access to the scientific and technical results.
Research strategy: NIB: Access to Excellence and presentation of best practices (opens in new window)In addition to monitoring progress and incorporating lessons learned, the draft strategy will include identifying future collaborations and discussing potential future pathways based on an analysis of SWOT and considering each partner's strategies. By learning from each other, we aim to become better, more recognisable, more social, and explore innovative approaches to increase the visibility and accessibility of cutting-edge research. Particular attention will be paid to shaping the consortium's funding portfolio over the life of the project and beyond, seeking, learning, and implementing synergies at multiple levels. Scientific gaps will be considered first, before gaps in support infrastructure are considered.
A protocol for the assessment of genomic instability in hepatic and lung 3D cell models (opens in new window)A detail protocol for the assessment of genomic instability in hepatic and lung 3D cell models will be prepared as a guideline for testing genotoxic activity of chemicals and nanoparticles. The protocol will contain all the necessary steps and information for the successful performance of the cytokinesis block micronucleus (CBMN) assay on hepatic and lung 3D cell models.
A guideline protocol for big data management (opens in new window)Using advanced platforms for high-throughput analysis such as Metafer and FlowSight, as well as spatial technologies and single-cell analysis, a significant amount of raw data, high-resolution images, and (meta-)data are generated, consuming large amounts of digital storage, thus requiring highly efficient tools for Big Data management. It also generates sensitive patient-related and scientific data. By sharing knowledge and best practices on data management and storage, protocols and documents with partner institutions and expert visits from SWAN, SU and VUmc to NIB, NIB will learn how to handle Big Data management and protect sensitive data through protected internal and external data storage options that ensure secure data storage and analysis. The expert exchange will establish general policy protocols that describe procedures and criteria for optimal data management and storage.
A protocol for the use of advanced platforms for high-throughput analysis of (geno)toxicological outcomes (opens in new window)A detail protocol how to use advanced platforms (e.g., MetaferTM system from MetaSystems and FlowSight imaging cytometry platform from Amnis) for medium and high-throughput automated analysis will be prepared as a guideline for testing genotoxic activity of chemicals and nanoparticles. The protocol will contain all the necessary steps and information how to use advanced platforms for the evaluation of genotoxic activity of chemicals and nanoparticles.
The final report on dissemination, exploitation and communication activities must be consistent with the DMP (Deliverable 2.1) and include explanations for any discrepancies. The final report shall include all communication and dissemination activities, including samples, and shall represent the activities of each partner and the consortium. A communication, dissemination, and exploitation protocol will be provided at the kick-off event at the beginning of the project and will be consistent with the grant and consortium agreement.
Publications
Author(s):
Jure Povšin, Timotej Sotošek, Metka Novak, Barbara Breznik
Published in:
Slovenian Veterinary Research, Issue 62, 2025, ISSN 2385-8761
Publisher:
University of Ljubljana
DOI:
10.26873/SVR-2029-2024
Author(s):
Urban Bogataj, Metka Novak, Simona Katrin Galun, Klementina Fon Tacer, Milos Vittori, Cornelis J.F. Van Noorden, Barbara Breznik
Published in:
Radiology and Oncology, Issue 59, 2025, ISSN 1581-3207
Publisher:
Walter de Gruyter GmbH
DOI:
10.2478/RAON-2025-0056
Author(s):
Martina Štampar, Bojana Žegura
Published in:
Mutation Research - Genetic Toxicology and Environmental Mutagenesis, Issue 900, 2025, ISSN 1383-5718
Publisher:
Elsevier BV
DOI:
10.1016/J.MRGENTOX.2024.503835
Author(s):
Iza Rozman, Alvaro Gallo-Cordova, María del Puerto Morales, Marco A. Morales Ovalle, Gerardo F. Goya, Katja Kološa, Domen Hočevar, Bojana Žegura, Alja Štern
Published in:
Biomedicine & Pharmacotherapy, Issue 195, 2026, ISSN 0753-3322
Publisher:
Elsevier BV
DOI:
10.1016/J.BIOPHA.2025.118950
Author(s):
Ezgi B Ulas, Sofie J I Koomen, Anne Vrijmoet, Ilias Houda, H Ibrahim Korkmaz, Chris Dickhoff, Idris Bahce, Suresh Senan, Tanja D de Gruijl, Marieke F Fransen, Teodora Radonic, Febe van Maldegem, Famke L Schneiders
Published in:
Journal for ImmunoTherapy of Cancer, Issue 13, 2025, ISSN 2051-1426
Publisher:
BMJ
DOI:
10.1136/JITC-2025-013237
Author(s):
Metka Novak, Bernarda Majc, Marta Malavolta, Andrej Porčnik, Jernej Mlakar, Matjaž Hren, Anamarija Habič, Mateja Mlinar, Ivana Jovčevska, Neja Šamec, Alja Zottel, Marija Skoblar Vidmar, Tina Vipotnik Vesnaver, Andrej Zupan, Alenka Matjašič, Saša Trkov Bobnar, Dejan Georgiev, Aleksander Sadikov, Roman Bošnjak, Borut Prestor, Radovan Komel, Tamara Lah Turnšek, Barbara Breznik
Published in:
Neuro-Oncology Advances, Issue 7, 2025, ISSN 2632-2498
Publisher:
Oxford University Press (OUP)
DOI:
10.1093/NOAJNL/VDAF015
Author(s):
Irma Durmišević, Anja Haverić, Sonja Žabkar, Alja Štern, Katja Kološa, Petra Jenuš Belec, Tamara Ćetković Pećar, Maida Hadžić Omanović, Sanjin Gutić, Iza Rozman, Sanin Haverić, Bojana Žegura
Published in:
Archives of Toxicology, 2026, ISSN 0340-5761
Publisher:
Springer Science and Business Media LLC
DOI:
10.1007/S00204-026-04336-9
Author(s):
Megan Cole, Panayiotis Anastasiou, Claudia Lee, Xiaofei Yu, Andrea de Castro, Jannes Roelink, Chris Moore, Edurne Mugarza, Martin Jones, Karishma Valand, Sareena Rana, Emma Colliver, Mihaela Angelova, Katey S. S. Enfield, Alastair Magness, Asher Mullokandov, Gavin Kelly, Tanja D. de Gruijl, Miriam Molina-Arcas, Charles Swanton, Julian Downward, Febe van Maldegem
Published in:
Science Advances, Issue 10, 2024, ISSN 2375-2548
Publisher:
American Association for the Advancement of Science (AAAS)
DOI:
10.1126/SCIADV.ADL6464
Author(s):
Emanuela Senjor, Anamarija Habič, Urban Švajger, Ana Mitrović, Matic Proj, Andrej Porčnik, Borut Prestor, Miha Jerala, Matic Bošnjak, Stanislav Gobec, Barbara Breznik, Janko Kos, Milica Perišić Nanut
Published in:
Frontiers in Immunology, Issue 16, 2025, ISSN 1664-3224
Publisher:
Frontiers Media SA
DOI:
10.3389/FIMMU.2025.1708281
Author(s):
Sendra Marta; Štampar Martina; Fras Katarina; Novoa Beatriz; Figueras Antonio; Žegura Bojana
Published in:
Environment International, Issue Volume 171, January 2023, 107721, 2023, ISSN 0160-4120
Publisher:
New York : Elsevier, 1978
DOI:
10.1016/J.ENVINT.2022.107721
Author(s):
Rebecca R. J. Collins, Rebecca R. Florke Gee, Sima Tozandehjani, Tara Bayat, Maria Camila Hoyos Sanchez, Juan Sebastian Solano Gutierrez, Barbara Breznik, Anna K. Lee, Samuel T. Peters, Jon P. Connelly, Shondra M. Pruett-Miller, Martine F. Roussel, Dinesh Rakheja, Heather S. Tillman, Patrick Ryan Potts, Klementina Fon Tacer
Published in:
Acta Neuropathologica Communications, Issue 13, 2025, ISSN 2051-5960
Publisher:
Springer Science and Business Media LLC
DOI:
10.1186/S40478-025-02055-3
Author(s):
Enfield KSS, Colliver E, Lee CSY, Magness A, Moore DA, Sivakumar M, Grigoriadis K, Pich O, Karasaki T, Hobson PS, Levi D, Veeriah S, Puttick C, Nye EL, Green M, Dijkstra KK, Shimato M, Akarca AU, Marafioti T, Salgado R, Hackshaw A, Consortium T, Jamal-Han
Published in:
Cancer Discovery, Issue 2024 Jun 3; 14(6): 1018–1047, 2024, ISSN 2159-8290
Publisher:
American Association for Cancer Research
DOI:
10.1158/2159-8290.CD-23-1380
Author(s):
Štampar Martina; Ravnjak Tim; Domijan Ana-Marija; Žegura Bojana
Published in:
Molecules, Issue Vol 28, Iss 7, p 3085 (2023), 2023, ISSN 1420-3049
Publisher:
MDPI
DOI:
10.3390/MOLECULES28073085
Author(s):
Bernarda Majc, Anamarija Habič, Marta Malavolta, Miloš Vittori, Andrej Porčnik, Roman Bošnjak, Jernej Mlakar, Alenka Matjašič, Andrej Zupan, Marija Skoblar Vidmar, Tamara Lah Turnšek, Aleksander Sadikov, Barbara Breznik, Metka Novak
Published in:
iScience, Issue 27, 2025, ISSN 2589-0042
Publisher:
Elsevier BV
DOI:
10.1016/J.ISCI.2024.110604
Author(s):
Vesna Kokondoska Grgič, Nika Marolt, Ajla Kubat, Tamara Dokmanović, Katja Kološa, Ivana Jovčevska, Tea Lanišnik Rižner
Published in:
Biomedicine & Pharmacotherapy, Issue 195, 2026, ISSN 0753-3322
Publisher:
Elsevier BV
DOI:
10.1016/J.BIOPHA.2026.119010
Author(s):
Anja Blazic, Bernarda Majc, Metka Novak, Barbara Breznik, Lea Rems
Published in:
Radiology and Oncology, Issue 59, 2025, ISSN 1581-3207
Publisher:
Walter de Gruyter GmbH
DOI:
10.2478/RAON-2025-0058
Author(s):
Alja Štern, Katja Kološa, Špela Rozman, Bojana Žegura
Published in:
Science of The Total Environment, Issue 1001, 2025, ISSN 0048-9697
Publisher:
Elsevier BV
DOI:
10.1016/J.SCITOTENV.2025.180527
Author(s):
Hooman Taleban, Xinzhong Li, Zulfiqur Ali, Karunakaran Kalesh, Jai Prakash, Tugba Bagci-Onder, Barbara Breznik
Published in:
Frontiers in Bioengineering and Biotechnology, Issue 13, 2026, ISSN 2296-4185
Publisher:
Frontiers Media SA
DOI:
10.3389/FBIOE.2025.1716813
Author(s):
Alja Zottel; Metka Novak; Neja Šamec; Bernarda Majc; Sara Colja; Mojca Katrašnik; Miloš Vittori; Barbara Hrastar; Ana Rotter; Andrej Porčnik; Tamara Lah Turnšek; Radovan Komel; Barbara Breznik; Ivana Jovčevska
Published in:
Cancers, Issue Volume 15, Issue 573 (2023), 2023, ISSN 2072-6694
Publisher:
MDPI
DOI:
10.3390/CANCERS15030573
Author(s):
Alja Štern; Matjaž Novak; Katja Kološa; Jurij Trontelj; Sonja Žabkar; Tjaša Šentjurc; Metka Filipič; Bojana Žegura
Published in:
Biomedicine & Pharmacotherapy, 2024, ISSN 1950-6007
Publisher:
Elsevier
DOI:
10.1016/J.BIOPHA.2024.116969
Author(s):
Sanz-Sagué B, Sáenz-Hernández A, Moreno Maldonado AC, Fuentes-García JA, Nuñez JM, Zegura B, Stern A, Kolosa K, Rozman I, Torres TE, Goya GF
Published in:
Chemico-Biological Interactions, Issue Volume 394, 1 May 2024, 110977, 2024, ISSN 0009-2797
Publisher:
Elsevier B.V.
DOI:
10.1016/J.CBI.2024.110977
Author(s):
Gillian E Conway, Bérénice Chavanel, François Virard, Ume-Kulsoom Shah, Michael J Burgum, Stephen J Evans, Michael Korenjak, Laura E Thomas, Gareth J Jenkins, Jiri Zavadil, Shareen H Doak
Published in:
Mutagenesis, 2025, ISSN 0267-8357
Publisher:
Oxford University Press (OUP)
DOI:
10.1093/MUTAGE/GEAF015
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