Project description
Drug discovery training platform with a focus on microbiota therapeutic modifications
Funded by the Marie Skłodowska-Curie Actions programme, the TALENTS project aims to build an international alliance for the interdisciplinary training of 15 doctoral candidates as next-generation drug researchers. Individual projects are structured to focus on the investigation of the microbiome and therapeutic modifications of the microbiota, alternatives to traditional antibiotics to lower the risk of resistance development, and means of delivering new therapeutic agents. The overarching goal is to develop new disease models and analytical methods. Discovering correlations and links between microbiota and disease origination, TALENTS will advance the discovery of innovative microbiome-modulating therapies.
Objective
TALENTS aims to build up an international programme for interdisciplinary and transsectorial training of 15 doctoral candidates (DCs) as needed for the next generation of drug researchers. Research projects are structured in 3 clusters (PCs): PC1 will investigate the microbiome by transcriptomic and metagenomic analysis of diseases to identify and isolate microorganisms/metabolites for therapeutically modifying the microbiota. PC2 will focus on pathoblockers targeting virulence factors as alternative to traditional antibiotics with lower risk of resistance development. PC3 will address the delivery needs across biological barriers, to achieve efficient and targeted transport to the site of action. Throughout the PC structure of 15 individual, but interconnected research projects, we aim to develop and exchange disease models, analytical methods and microbiome-related results. By generating knowledge on correlations and causalities between microbiota and disease TALENTS will advance the development of novel microbiome-modulating therapies
TALENTS is builds on an earlier joint venture of Saarland University, University Clinics Saarland and Helmholtz Institute for Pharmaceutical Research Saarland to foster transdisciplinary doctoral training between different faculties and institutions. In addition, TALENTS is intersectorial by implementing a unique supervision structure for each DC with an external expert advisor and translation-oriented training for individual career development, also including secondments in a complementary industrial or clinical sector. Working on challenging research projects, the candidates will acquire specific knowledge and skills at the interface of clinical medicine, microbiology and pharmaceutical science, pivotal for state-of-the-art infection research and microbiome interventions.
By collaborations of experts from natural sciences, medicine, and bioinformatics, TALENTS provides high-level multidisciplinary and intersectorial training.
Fields of science
Not validated
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Keywords
Programme(s)
- HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA) Main Programme
Coordinator
66123 Saarbrucken
Germany
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Partners (16)
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38124 Braunschweig
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66123 Saarbruecken
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
66121 Saarbrücken
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
22419 Hamburg
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
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68330 Huningue
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
66802 Uberherrn
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
66129 Saarbruecken
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
53757 Sankt Augustin
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G12 8QQ Glasgow
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4040 Linz
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10117 Berlin
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48149 MUENSTER
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10589 Berlin
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9052 ZWIJNAARDE - GENT
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
66123 Saarbrucken
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
91054 Erlangen
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