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NANOTECHNOLOGY-ENABLED DETECTION OF CLINICALLY RELEVANT ANTIBODIES FOR EARLY CANCER DIAGNOSIS AND IMMUNOTHERAPY MONITORING

Descripción del proyecto

Formación en detección de anticuerpos basada en nanotecnologías

La detección de anticuerpos en los fluidos corporales permite informar a profesionales clínicos sobre el contacto de una persona con diversos microorganismos patógenos, así como diagnosticar enfermedades autoinmunes o de otro tipo. Sin embargo, a pesar de su amplia aplicación, los ensayos serológicos carecen tanto de sensibilidad como de especificidad, por lo que es necesario seguir buscando métodos alternativos. El equipo del proyecto Nano-ImmunoEra, financiado por las Acciones Marie Skłodowska-Curie, tiene como objetivo principal desarrollar biosensores y herramientas de diagnóstico basados en nanotecnologías para la detección de anticuerpos clínicamente relevantes. En el proyecto se realizan fundamentalmente actividades para la formación de la próxima generación de científicos en el ámbito de las ciencias de los materiales, la nanotecnología, la biología molecular y los biosensores.

Objetivo

Nano-ImmunoEra is a research and innovation staff exchange network aiming at the development of innovative biosensors and diagnostic tools for the detection of clinically relevant antibodies. Nano-ImmunoEra will form the next generation of clinically-oriented analytical scientists capable of delivering innovative solutions that will improve the lives of patients, reduce the cost of healthcare and position Europe as a leader in biomedical devices. Since standard laboratory-based methodologies and disposable tests present several analytical limitations, we have selected antibodies as molecular targets of this project because their rapid, sensitive and specific detection in bodily fluids still represent a significant diagnostic challenge. To deliver these goals, we have assembled a highly inter- and multidisciplinary and multicultural team of European as well as strategic non-EU Countries (USA, Switzerland and South Africa) through the collaboration among 7 academic institutions and 2 non-academic partners to enable ultimate impact to the healthcare. The expertise of different and multidisciplinary research teams, comprised of PhD and Postdoctoral as well as experienced researchers from Universities and companies, will endow Nano-ImmunoEra with a strong intersectoral dimension, which is of high importance for a broad and effective impact of the project. In addition, this program involves key participation of junior researchers with exceptional scientific backgrounds and accomplishments, and will provide strong support for the development of their careers. The transfer of knowledge and related training activities aim to provide scientists achieving specific competences in the field of materials sciences, nanotechnology, molecular biology and biosensors.

Coordinador

ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Aportación neta de la UEn
€ 128 800,00
Dirección
VIA ZAMBONI 33
40126 Bologna
Italia

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Región
Nord-Est Emilia-Romagna Bologna
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
Sin datos

Participantes (4)

Socios (4)