BIOMAT4CAST - PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY MULTI-SCALE IN SILICO LABORATORY FOR COMPLEX AND SMART BIOMATERIALS

Project Information

BioMat4CAST

Grant agreement ID: 101086667

DOI

10.3030/101086667

EC signature date 10 November 2022

Start date 1 December 2022

End date 30 November 2027

Funded under

• Widening participation and spreading excellence

Total cost

€ 2 500 000,00

EU contribution

€ 2 500 000,00

Coordinated by

INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI
Romania

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan

Documents, reports (5)

BioMat4CAST group Sustainability plan
Periodic report on BioMat4CAST research activities -1

First periodic report on BioMat4CAST research activities

BioMat4CAST Dissemination, Exploitation and Communication Plan
Report on training and Human Resources Management 1

First periodic report on HRM

BioMat4CAST Scientific and Management Strategy

BioMat4CAST Scientific and Management Strategy elaborated by the ERA Chair and the Management Team in ICMPP and discussed with the IAB

Websites, patent fillings, videos etc. (1)

BioMat4CAST project webpage

Publications

Peer reviewed articles (16)

Multi-shell gold nanoparticles functionalized with methotrexate: a novel nanotherapeutic approach for improved antitumoral and antioxidant activity and enhanced biocompatibility

Author(s): Denisse-Iulia Bostiog, Natalia Simionescu, Adina Coroaba, Ioana C. Marinas, Mariana C. Chifiriuc, Gratiela Gradisteanu Pircalabioru, Stelian S. Maier, Mariana Pinteala
Published in: Drug Delivery, Issue 31, 2024, ISSN 1071-7544
Publisher: Informa UK Limited
DOI: 10.1080/10717544.2024.2388624

Unusual bending patterns of spermidine3+ bound to DNA double helix

Author(s): S. Perepelytsya, T. Vasiliu, A. Laaksonen, L. De Villiers Engelbrecht, F. Mocci
Published in: Low Temp. Phys., Issue 50, 204–214, 2024, ISSN 1090-6517
Publisher: AIP
DOI: 10.1063/10.0024969

New Library of Iodo-Quinoline Derivatives Obtained by an Alternative Synthetic Pathway and Their Antimicrobial Activity;

Author(s): C. M. Al-Matarneh, A. Nicolescu, I. C. Marinaş, M. D. Găboreanu, S. Shova, A. Dascălu, M. Silion, M. Pinteală;
Published in: Molecules, Issue 29, 772, 2024, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules29040772

Synthetic Approaches to Novel Human Carbonic Anhydrase Isoform Inhibitors Based on Pyrrol-2-one Moiety

Author(s): Cristina M. Al-Matarneh, M. Pinteala, A. Nicolescu, M. Silion, F. Mocci, R. Puf, A. Angeli, M. Ferraroni, C. T. Supuran, S. Zara, S. Carradori, N. Paoletti, A. Bonardi, P. Gratteri,
Published in: J of Medicinal Chemistry, 2024, ISSN 0022-2623
Publisher: American Chemical Society
DOI: 10.1021/acs.jmedchem.3c02190

Molecular dynamics simulations reveal the hidden EF-hand of EF-SAM as a possible key thermal sensor for STIM1 activation by temperature

Author(s): Andrei Neamtu, Dragomir N. Serban, Greg J. Barrit, Dragos Lucian Isac, Tudor Vasiliu, Aatto Laaksonen, Ionela Lacramioara Serban
Published in: Journal Biological Chemistry, Issue 299, 2023, ISSN 0021-9258
Publisher: ELSEVIER
DOI: 10.1016/j.jbc.2023.104970

Radiolabeled multi-layered coated gold nanoparticles as potential biocompatible PET/SPECT tracers

Author(s): Cristina M. Uritu, Cristina M. Al-Matarneh, Denisse I. Bostiog, Adina Coroaba, Vlad Ghizdovat, Silviu I. Filipiuc, Natalia Simionescu, Cipriana Stefanescu, Wael Jalloul, Valentin Nastasa, Bogdan I. Tamba, Stelian S. Maier, Mariana Pinteala
Published in: Journal of Materials Chemistry B, 2024, ISSN 2050-7518
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3tb02654j

Conformational flexibility of spermidine3+ interacting with DNA double helix

Author(s): Sergiy Perepelytsya, Tudor Vasiliu, Aatto Laaksonen, Leon De Villiers Engelbrecht, Giuseppe Brancatoj, Francesca Mocci
Published in: Journal of Molecular Liquids 389 (2023) 122828, Issue 389, 2023, ISSN 0167-7322
Publisher: Elsevier BV
DOI: 10.1016/j.molliq.2023.122828

Stimuli-responsive laccase/chitosan-g-PNIPAM complexes: A sustainable strategy for biodegradation of organic pollutants

Author(s): Larisa-Maria Petrila, Maria Karayianni, Tudor Vasiliu, Răzvan Puf, Marcela Mihai, Stergios Pispas
Published in: International Journal of Biological Macromolecules, Issue 322, 2025, ISSN 0141-8130
Publisher: Elsevier BV
DOI: 10.1016/J.IJBIOMAC.2025.146754

Deep Eutectic Solvents Meet Non-Aqueous Cosolvents: A Modeling and Simulation Perspective─A Tutorial Review

Author(s): Leon de Villiers Engelbrecht, Narcis Cibotariu, Xiaoyan Ji, Aatto Laaksonen, Francesca Mocci
Published in: Journal of Chemical & Engineering Data, Issue 70, 2025, ISSN 0021-9568
Publisher: American Chemical Society (ACS)
DOI: 10.1021/acs.jced.4c00505

Beyond poly(NIPAAm): Molecularly engineered biodegradable pullulan microgels with excellent thermosensitivity. Design, modeling, and realization

Author(s): Razvan Puf, Gheorghe Fundueanu, Marieta Constantin, Adina Ferariu, Aatto Laaksonen
Published in: Chemical Engineering Journal, 2025, ISSN 1385-8947
Publisher: Elsevier BV
DOI: 10.1016/J.CEJ.2025.167673

Cosolvent effects on the complexation of the antifungal propiconazole nitrate with β-cyclodextrin: a combined molecular dynamics and NMR study

Author(s): Dragos L. Isac, Petru Tîrnovan, Alina Nicolescu, Adrian Fifere, Andrei Neamtu, Mariana Pinteala
Published in: European Journal of Pharmaceutical Sciences, 2025, ISSN 0928-0987
Publisher: Elsevier BV
DOI: 10.1016/J.EJPS.2025.107248

Revealing the supramolecular interactions of the bis(azopyrenyl) dibenzo-18-crown-6-ether system

Author(s): Adina Coroaba, Cristina Al-Matarneh, Tudor Vasiliu, Sorin-Alexandru Ibanescu, Radu Zonda, Irina Esanu, Dragos-Lucian Isac , Mariana Pinteala
Published in: Journal of Molecular Liquids,, Issue 374, 2023, ISSN 0167-7322
Publisher: Elsevier BV
DOI: 10.1016/j.molliq.2023.121298

Nucleic acid-binding bis-acridine orange dyes with improved properties for bioimaging and PCR applications

Author(s): Olesia Kulyk, Alexander Krivoshey, Olga Kolosova, Ivanna Prylutska, Tudor Vasiliu, Razvan Puf, Francesca Mocci, Aatto Laaksonen, Sergiy Perepelytsya, Dmytro Kobzev, Rostyslav Svoiakov, Zenoviy Tkachuk, Anatoliy Tatarets
Published in: Journal of Materials Chemistry B, Issue 12, 2024, ISSN 2050-750X
Publisher: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4TB01775G

Signature of electronically excited states in Raman spectra of azobenzene derivatives. Computational and experimental approaches

Author(s): Dragos Lucian Isac, Emilian Rosca, Anton Airinei, Elena Laura Ursu, Razvan Puf, Isabela Costinela Man, Andrei Neamtu, Aatto Laaksonen
Published in: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, ISSN 1386-1425
Publisher: Elsevier BV
DOI: 10.1016/j.saa.2025.125828

Novel 3-Sulfonamide Dual-Tail Pyrrol-2-one Bridged Molecules as Potent Human Carbonic Anhydrase Isoform Inhibitors: Design, Synthesis, Molecular Modeling Investigation, and Anticancer Activity in MeWo, SK-BR-3, and MG-63 Cell Lines

Author(s): Cristina M. Al-Matarneh, Natalia Simionescu, Alina Nicolescu, Mihaela Silion, Andrea Angeli, Niccolò Paoletti, Alessandro Bonardi, Paola Gratteri, Mariana Pinteala, Claudiu T. Supuran
Published in: Journal of Medicinal Chemistry, 2025, ISSN 0022-2623
Publisher: American Chemical Society (ACS)
DOI: 10.1021/acs.jmedchem.4c02586

Revisiting Fused‐Pyrrolo‐1,10‐Phenanthroline Derivatives: Novel Transformations and Stability Studies

Author(s): Cristina M. Al Matarneh, Alina Nicolescu, Sergiu Shova, Mircea Apostu, Razvan Puf, Francesca Mocci, Aatto Laaksonen, Ionel I. Mangalagiu, Ramona Danac
Published in: ChemistryOpen, Issue 14, 2025, ISSN 2191-1363
Publisher: Wiley
DOI: 10.1002/OPEN.202400365