BIOMAT4CAST - PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY MULTI-SCALE IN SILICO LABORATORY FOR COMPLEX AND SMART BIOMATERIALS

Informations projet

BioMat4CAST

N° de convention de subvention: 101086667

DOI

10.3030/101086667

Date de signature de la CE 10 Novembre 2022

Date de début 1 Decembre 2022

Date de fin 30 Novembre 2027

Financé au titre de

• Widening participation and spreading excellence

Coût total

€ 2 500 000,00

Contribution de l’UE

€ 2 500 000,00

Coordonné par

INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI
Romania

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Data Management Plan (1)

Data Management Plan

Documents, reports (5)

BioMat4CAST group Sustainability plan
Periodic report on BioMat4CAST research activities -1

First periodic report on BioMat4CAST research activities

BioMat4CAST Dissemination, Exploitation and Communication Plan
Report on training and Human Resources Management 1

First periodic report on HRM

BioMat4CAST Scientific and Management Strategy

BioMat4CAST Scientific and Management Strategy elaborated by the ERA Chair and the Management Team in ICMPP and discussed with the IAB

Websites, patent fillings, videos etc. (1)

BioMat4CAST project webpage

Publications

Peer reviewed articles (16)

Multi-shell gold nanoparticles functionalized with methotrexate: a novel nanotherapeutic approach for improved antitumoral and antioxidant activity and enhanced biocompatibility

Auteurs: Denisse-Iulia Bostiog, Natalia Simionescu, Adina Coroaba, Ioana C. Marinas, Mariana C. Chifiriuc, Gratiela Gradisteanu Pircalabioru, Stelian S. Maier, Mariana Pinteala
Publié dans: Drug Delivery, Numéro 31, 2024, ISSN 1071-7544
Éditeur: Informa UK Limited
DOI: 10.1080/10717544.2024.2388624

Unusual bending patterns of spermidine3+ bound to DNA double helix

Auteurs: S. Perepelytsya, T. Vasiliu, A. Laaksonen, L. De Villiers Engelbrecht, F. Mocci
Publié dans: Low Temp. Phys., Numéro 50, 204–214, 2024, ISSN 1090-6517
Éditeur: AIP
DOI: 10.1063/10.0024969

New Library of Iodo-Quinoline Derivatives Obtained by an Alternative Synthetic Pathway and Their Antimicrobial Activity;

Auteurs: C. M. Al-Matarneh, A. Nicolescu, I. C. Marinaş, M. D. Găboreanu, S. Shova, A. Dascălu, M. Silion, M. Pinteală;
Publié dans: Molecules, Numéro 29, 772, 2024, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules29040772

Synthetic Approaches to Novel Human Carbonic Anhydrase Isoform Inhibitors Based on Pyrrol-2-one Moiety

Auteurs: Cristina M. Al-Matarneh, M. Pinteala, A. Nicolescu, M. Silion, F. Mocci, R. Puf, A. Angeli, M. Ferraroni, C. T. Supuran, S. Zara, S. Carradori, N. Paoletti, A. Bonardi, P. Gratteri,
Publié dans: J of Medicinal Chemistry, 2024, ISSN 0022-2623
Éditeur: American Chemical Society
DOI: 10.1021/acs.jmedchem.3c02190

Molecular dynamics simulations reveal the hidden EF-hand of EF-SAM as a possible key thermal sensor for STIM1 activation by temperature

Auteurs: Andrei Neamtu, Dragomir N. Serban, Greg J. Barrit, Dragos Lucian Isac, Tudor Vasiliu, Aatto Laaksonen, Ionela Lacramioara Serban
Publié dans: Journal Biological Chemistry, Numéro 299, 2023, ISSN 0021-9258
Éditeur: ELSEVIER
DOI: 10.1016/j.jbc.2023.104970

Radiolabeled multi-layered coated gold nanoparticles as potential biocompatible PET/SPECT tracers

Auteurs: Cristina M. Uritu, Cristina M. Al-Matarneh, Denisse I. Bostiog, Adina Coroaba, Vlad Ghizdovat, Silviu I. Filipiuc, Natalia Simionescu, Cipriana Stefanescu, Wael Jalloul, Valentin Nastasa, Bogdan I. Tamba, Stelian S. Maier, Mariana Pinteala
Publié dans: Journal of Materials Chemistry B, 2024, ISSN 2050-7518
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d3tb02654j

Conformational flexibility of spermidine3+ interacting with DNA double helix

Auteurs: Sergiy Perepelytsya, Tudor Vasiliu, Aatto Laaksonen, Leon De Villiers Engelbrecht, Giuseppe Brancatoj, Francesca Mocci
Publié dans: Journal of Molecular Liquids 389 (2023) 122828, Numéro 389, 2023, ISSN 0167-7322
Éditeur: Elsevier BV
DOI: 10.1016/j.molliq.2023.122828

Stimuli-responsive laccase/chitosan-g-PNIPAM complexes: A sustainable strategy for biodegradation of organic pollutants

Auteurs: Larisa-Maria Petrila, Maria Karayianni, Tudor Vasiliu, Răzvan Puf, Marcela Mihai, Stergios Pispas
Publié dans: International Journal of Biological Macromolecules, Numéro 322, 2025, ISSN 0141-8130
Éditeur: Elsevier BV
DOI: 10.1016/J.IJBIOMAC.2025.146754

Deep Eutectic Solvents Meet Non-Aqueous Cosolvents: A Modeling and Simulation Perspective─A Tutorial Review

Auteurs: Leon de Villiers Engelbrecht, Narcis Cibotariu, Xiaoyan Ji, Aatto Laaksonen, Francesca Mocci
Publié dans: Journal of Chemical & Engineering Data, Numéro 70, 2025, ISSN 0021-9568
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/acs.jced.4c00505

Beyond poly(NIPAAm): Molecularly engineered biodegradable pullulan microgels with excellent thermosensitivity. Design, modeling, and realization

Auteurs: Razvan Puf, Gheorghe Fundueanu, Marieta Constantin, Adina Ferariu, Aatto Laaksonen
Publié dans: Chemical Engineering Journal, 2025, ISSN 1385-8947
Éditeur: Elsevier BV
DOI: 10.1016/J.CEJ.2025.167673

Cosolvent effects on the complexation of the antifungal propiconazole nitrate with β-cyclodextrin: a combined molecular dynamics and NMR study

Auteurs: Dragos L. Isac, Petru Tîrnovan, Alina Nicolescu, Adrian Fifere, Andrei Neamtu, Mariana Pinteala
Publié dans: European Journal of Pharmaceutical Sciences, 2025, ISSN 0928-0987
Éditeur: Elsevier BV
DOI: 10.1016/J.EJPS.2025.107248

Revealing the supramolecular interactions of the bis(azopyrenyl) dibenzo-18-crown-6-ether system

Auteurs: Adina Coroaba, Cristina Al-Matarneh, Tudor Vasiliu, Sorin-Alexandru Ibanescu, Radu Zonda, Irina Esanu, Dragos-Lucian Isac , Mariana Pinteala
Publié dans: Journal of Molecular Liquids,, Numéro 374, 2023, ISSN 0167-7322
Éditeur: Elsevier BV
DOI: 10.1016/j.molliq.2023.121298

Nucleic acid-binding bis-acridine orange dyes with improved properties for bioimaging and PCR applications

Auteurs: Olesia Kulyk, Alexander Krivoshey, Olga Kolosova, Ivanna Prylutska, Tudor Vasiliu, Razvan Puf, Francesca Mocci, Aatto Laaksonen, Sergiy Perepelytsya, Dmytro Kobzev, Rostyslav Svoiakov, Zenoviy Tkachuk, Anatoliy Tatarets
Publié dans: Journal of Materials Chemistry B, Numéro 12, 2024, ISSN 2050-750X
Éditeur: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4TB01775G

Signature of electronically excited states in Raman spectra of azobenzene derivatives. Computational and experimental approaches

Auteurs: Dragos Lucian Isac, Emilian Rosca, Anton Airinei, Elena Laura Ursu, Razvan Puf, Isabela Costinela Man, Andrei Neamtu, Aatto Laaksonen
Publié dans: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, ISSN 1386-1425
Éditeur: Elsevier BV
DOI: 10.1016/j.saa.2025.125828

Novel 3-Sulfonamide Dual-Tail Pyrrol-2-one Bridged Molecules as Potent Human Carbonic Anhydrase Isoform Inhibitors: Design, Synthesis, Molecular Modeling Investigation, and Anticancer Activity in MeWo, SK-BR-3, and MG-63 Cell Lines

Auteurs: Cristina M. Al-Matarneh, Natalia Simionescu, Alina Nicolescu, Mihaela Silion, Andrea Angeli, Niccolò Paoletti, Alessandro Bonardi, Paola Gratteri, Mariana Pinteala, Claudiu T. Supuran
Publié dans: Journal of Medicinal Chemistry, 2025, ISSN 0022-2623
Éditeur: American Chemical Society (ACS)
DOI: 10.1021/acs.jmedchem.4c02586

Revisiting Fused‐Pyrrolo‐1,10‐Phenanthroline Derivatives: Novel Transformations and Stability Studies

Auteurs: Cristina M. Al Matarneh, Alina Nicolescu, Sergiu Shova, Mircea Apostu, Razvan Puf, Francesca Mocci, Aatto Laaksonen, Ionel I. Mangalagiu, Ramona Danac
Publié dans: ChemistryOpen, Numéro 14, 2025, ISSN 2191-1363
Éditeur: Wiley
DOI: 10.1002/OPEN.202400365