BIOMAT4CAST - PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY MULTI-SCALE IN SILICO LABORATORY FOR COMPLEX AND SMART BIOMATERIALS

Información del proyecto

BioMat4CAST

Identificador del acuerdo de subvención: 101086667

DOI

10.3030/101086667

Fecha de la firma de la CE 10 Noviembre 2022

Fecha de inicio 1 Diciembre 2022

Fecha de finalización 30 Noviembre 2027

Financiado con arreglo a

• Widening participation and spreading excellence

Coste total

€ 2 500 000,00

Aportación de la UE

€ 2 500 000,00

Coordinado por

INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI
Romania

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Data Management Plan (1)

Data Management Plan

Documents, reports (5)

BioMat4CAST group Sustainability plan
Periodic report on BioMat4CAST research activities -1

First periodic report on BioMat4CAST research activities

BioMat4CAST Dissemination, Exploitation and Communication Plan
Report on training and Human Resources Management 1

First periodic report on HRM

BioMat4CAST Scientific and Management Strategy

BioMat4CAST Scientific and Management Strategy elaborated by the ERA Chair and the Management Team in ICMPP and discussed with the IAB

Websites, patent fillings, videos etc. (1)

BioMat4CAST project webpage

Publicaciones

Peer reviewed articles (16)

Multi-shell gold nanoparticles functionalized with methotrexate: a novel nanotherapeutic approach for improved antitumoral and antioxidant activity and enhanced biocompatibility

Autores: Denisse-Iulia Bostiog, Natalia Simionescu, Adina Coroaba, Ioana C. Marinas, Mariana C. Chifiriuc, Gratiela Gradisteanu Pircalabioru, Stelian S. Maier, Mariana Pinteala
Publicado en: Drug Delivery, Edición 31, 2024, ISSN 1071-7544
Editor: Informa UK Limited
DOI: 10.1080/10717544.2024.2388624

Unusual bending patterns of spermidine3+ bound to DNA double helix

Autores: S. Perepelytsya, T. Vasiliu, A. Laaksonen, L. De Villiers Engelbrecht, F. Mocci
Publicado en: Low Temp. Phys., Edición 50, 204–214, 2024, ISSN 1090-6517
Editor: AIP
DOI: 10.1063/10.0024969

New Library of Iodo-Quinoline Derivatives Obtained by an Alternative Synthetic Pathway and Their Antimicrobial Activity;

Autores: C. M. Al-Matarneh, A. Nicolescu, I. C. Marinaş, M. D. Găboreanu, S. Shova, A. Dascălu, M. Silion, M. Pinteală;
Publicado en: Molecules, Edición 29, 772, 2024, ISSN 1420-3049
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules29040772

Synthetic Approaches to Novel Human Carbonic Anhydrase Isoform Inhibitors Based on Pyrrol-2-one Moiety

Autores: Cristina M. Al-Matarneh, M. Pinteala, A. Nicolescu, M. Silion, F. Mocci, R. Puf, A. Angeli, M. Ferraroni, C. T. Supuran, S. Zara, S. Carradori, N. Paoletti, A. Bonardi, P. Gratteri,
Publicado en: J of Medicinal Chemistry, 2024, ISSN 0022-2623
Editor: American Chemical Society
DOI: 10.1021/acs.jmedchem.3c02190

Molecular dynamics simulations reveal the hidden EF-hand of EF-SAM as a possible key thermal sensor for STIM1 activation by temperature

Autores: Andrei Neamtu, Dragomir N. Serban, Greg J. Barrit, Dragos Lucian Isac, Tudor Vasiliu, Aatto Laaksonen, Ionela Lacramioara Serban
Publicado en: Journal Biological Chemistry, Edición 299, 2023, ISSN 0021-9258
Editor: ELSEVIER
DOI: 10.1016/j.jbc.2023.104970

Radiolabeled multi-layered coated gold nanoparticles as potential biocompatible PET/SPECT tracers

Autores: Cristina M. Uritu, Cristina M. Al-Matarneh, Denisse I. Bostiog, Adina Coroaba, Vlad Ghizdovat, Silviu I. Filipiuc, Natalia Simionescu, Cipriana Stefanescu, Wael Jalloul, Valentin Nastasa, Bogdan I. Tamba, Stelian S. Maier, Mariana Pinteala
Publicado en: Journal of Materials Chemistry B, 2024, ISSN 2050-7518
Editor: Royal Society of Chemistry
DOI: 10.1039/d3tb02654j

Conformational flexibility of spermidine3+ interacting with DNA double helix

Autores: Sergiy Perepelytsya, Tudor Vasiliu, Aatto Laaksonen, Leon De Villiers Engelbrecht, Giuseppe Brancatoj, Francesca Mocci
Publicado en: Journal of Molecular Liquids 389 (2023) 122828, Edición 389, 2023, ISSN 0167-7322
Editor: Elsevier BV
DOI: 10.1016/j.molliq.2023.122828

Stimuli-responsive laccase/chitosan-g-PNIPAM complexes: A sustainable strategy for biodegradation of organic pollutants

Autores: Larisa-Maria Petrila, Maria Karayianni, Tudor Vasiliu, Răzvan Puf, Marcela Mihai, Stergios Pispas
Publicado en: International Journal of Biological Macromolecules, Edición 322, 2025, ISSN 0141-8130
Editor: Elsevier BV
DOI: 10.1016/J.IJBIOMAC.2025.146754

Deep Eutectic Solvents Meet Non-Aqueous Cosolvents: A Modeling and Simulation Perspective─A Tutorial Review

Autores: Leon de Villiers Engelbrecht, Narcis Cibotariu, Xiaoyan Ji, Aatto Laaksonen, Francesca Mocci
Publicado en: Journal of Chemical & Engineering Data, Edición 70, 2025, ISSN 0021-9568
Editor: American Chemical Society (ACS)
DOI: 10.1021/acs.jced.4c00505

Beyond poly(NIPAAm): Molecularly engineered biodegradable pullulan microgels with excellent thermosensitivity. Design, modeling, and realization

Autores: Razvan Puf, Gheorghe Fundueanu, Marieta Constantin, Adina Ferariu, Aatto Laaksonen
Publicado en: Chemical Engineering Journal, 2025, ISSN 1385-8947
Editor: Elsevier BV
DOI: 10.1016/J.CEJ.2025.167673

Cosolvent effects on the complexation of the antifungal propiconazole nitrate with β-cyclodextrin: a combined molecular dynamics and NMR study

Autores: Dragos L. Isac, Petru Tîrnovan, Alina Nicolescu, Adrian Fifere, Andrei Neamtu, Mariana Pinteala
Publicado en: European Journal of Pharmaceutical Sciences, 2025, ISSN 0928-0987
Editor: Elsevier BV
DOI: 10.1016/J.EJPS.2025.107248

Revealing the supramolecular interactions of the bis(azopyrenyl) dibenzo-18-crown-6-ether system

Autores: Adina Coroaba, Cristina Al-Matarneh, Tudor Vasiliu, Sorin-Alexandru Ibanescu, Radu Zonda, Irina Esanu, Dragos-Lucian Isac , Mariana Pinteala
Publicado en: Journal of Molecular Liquids,, Edición 374, 2023, ISSN 0167-7322
Editor: Elsevier BV
DOI: 10.1016/j.molliq.2023.121298

Nucleic acid-binding bis-acridine orange dyes with improved properties for bioimaging and PCR applications

Autores: Olesia Kulyk, Alexander Krivoshey, Olga Kolosova, Ivanna Prylutska, Tudor Vasiliu, Razvan Puf, Francesca Mocci, Aatto Laaksonen, Sergiy Perepelytsya, Dmytro Kobzev, Rostyslav Svoiakov, Zenoviy Tkachuk, Anatoliy Tatarets
Publicado en: Journal of Materials Chemistry B, Edición 12, 2024, ISSN 2050-750X
Editor: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4TB01775G

Signature of electronically excited states in Raman spectra of azobenzene derivatives. Computational and experimental approaches

Autores: Dragos Lucian Isac, Emilian Rosca, Anton Airinei, Elena Laura Ursu, Razvan Puf, Isabela Costinela Man, Andrei Neamtu, Aatto Laaksonen
Publicado en: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, ISSN 1386-1425
Editor: Elsevier BV
DOI: 10.1016/j.saa.2025.125828

Novel 3-Sulfonamide Dual-Tail Pyrrol-2-one Bridged Molecules as Potent Human Carbonic Anhydrase Isoform Inhibitors: Design, Synthesis, Molecular Modeling Investigation, and Anticancer Activity in MeWo, SK-BR-3, and MG-63 Cell Lines

Autores: Cristina M. Al-Matarneh, Natalia Simionescu, Alina Nicolescu, Mihaela Silion, Andrea Angeli, Niccolò Paoletti, Alessandro Bonardi, Paola Gratteri, Mariana Pinteala, Claudiu T. Supuran
Publicado en: Journal of Medicinal Chemistry, 2025, ISSN 0022-2623
Editor: American Chemical Society (ACS)
DOI: 10.1021/acs.jmedchem.4c02586

Revisiting Fused‐Pyrrolo‐1,10‐Phenanthroline Derivatives: Novel Transformations and Stability Studies

Autores: Cristina M. Al Matarneh, Alina Nicolescu, Sergiu Shova, Mircea Apostu, Razvan Puf, Francesca Mocci, Aatto Laaksonen, Ionel I. Mangalagiu, Ramona Danac
Publicado en: ChemistryOpen, Edición 14, 2025, ISSN 2191-1363
Editor: Wiley
DOI: 10.1002/OPEN.202400365