Project description
Neuronal-vascular association in neonates
The brain regulates its own blood flow to meet the high metabolic and energy demands through a mechanism known as neurovascular coupling. Blood oxygenation level-dependent (BOLD) technique is a non-invasive method used to measure brain activity by quantifying the changes in tissue oxygenation and blood flow. Studies in newborns using BOLD indicate an unexplained variation, potentially offering an avenue for better understanding of brain development and haemodynamics. The EU-funded 2BOLD project aims to resolve spatiotemporal changes in haemodynamics during brain development to understand neurovascular coupling. Using a mouse model, researchers will combine haemodynamic and vascular data alongside metabolic activity measurements to decipher the mechanism.
Fields of science
Programme(s)
Funding Scheme
HORIZON-AG-UN - HORIZON Unit Grant
Coordinator
3004-531 Coimbra
Portugal
See on map