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ANTIMICROBIAL NANOSTRUCTURED BIOMATERIALS FOR COMPLEX WOUND HEALING

Project description

A cost-effective wound healing agent

Complex wounds such as diabetic or venous ulcers, or chronic wounds from burns are difficult to treat and slow to heal, thereby increasing the risk of infection. Silver is widely used as an antimicrobial agent in the treatment of wound infections. However, its production is costly and environmentally unsafe. To address this medical challenge, the EU-funded NABIHEAL project aims to develop multifunctional nanotechnology-based materials as an affordable alternative to silver for wound healing. These proposed biomaterials will also allow for the controlled release of therapeutic molecules in wound dressings, preventing biofilm formation and facilitating healing.

Objective

Complex wounds are a global health problem with significant impact on the health care economy. In developed countries alone, they impact the quality of life of more than 2% of total population. Complex wounds, including chronic wounds or major burns, are highly susceptible to microbial infection and biofilm formation, and difficult to treat. Moreover, silver is a widely used metal in antimicrobial products to treat wound infections. However, silver-based products are expensive, and show several drawbacks due to costs, as well as environmental and safety concerns.
The NABIHEAL project will develop multifunctional biomaterials, from proof-of-concept (TRL 3) to the preclinical regulatory stage (TRL 5), to improve wound management. The resulting biomaterials will enable affordable treatment of wound infections or prevention of complications during all phases of the wound healing process.
In the short and medium term, NABIHEAL will develop at least two innovative multifunctional wound-healing biomaterials, using affordable EU-based manufacturing technologies. In the long term, NABIHEAL could become a game-changing alternative to silver in wound-healing dressings.
A consortium comprising 5 SMEs and 9 academic institutions, with expertise in wound healing product development, evaluation and commercialization, nanotechnology, safety, and regulatory affairs, will join forces to address these ambitious objectives.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Coordinator

CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED M.P.
Net EU contribution
€ 981 420,11
Address
CALLE MONFORTE DE LEMOS 5
28029 Madrid
Spain

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Research Organisations
Links
Total cost
€ 1 258 740,90

Participants (14)

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