Descrizione del progetto
Un agente economico per la guarigione delle ferite
Le ferite complesse, come le ulcere diabetiche o venose, o le ferite croniche da ustioni, sono difficili da trattare e guariscono lentamente, aumentando il rischio di infezioni. In questi casi si fa ampio utilizzo dell’argento come agente antimicrobico, ma la sua produzione è costosa e poco sicura dal punto di vista ambientale. Per affrontare questa sfida medica, il progetto NABIHEAL, finanziato dall’UE, mira a sviluppare materiali multifunzionali basati sulle nanotecnologie come alternativa economica all’argento per la guarigione delle ferite. I biomateriali proposti consentiranno anche il rilascio controllato di molecole terapeutiche nelle medicazioni delle ferite, prevenendo la formazione di biofilm e agevolando la guarigione.
Obiettivo
Complex wounds impact the quality of life of more than 2% of total population in developed countries being a global health problem with significantly impacts on health care economy. Complex wounds, including chronic wounds or major burns, are highly susceptible to microbial infection and biofilm formation, difficult to treat. Silver is a metal widely used in antimicrobial products to treat wound infections. However, silver-based products are expensive, and show several drawbacks due to costs, and environmental and safety concerns. NABIHEAL project will develop, from PoC (TRL3) to preclinical regulatory (TRL5), multifunctional biomaterials to solve some of the unmet medical needs in wound management, obtaining affordable treatments of wound infections or prevention of complications during all phases of wound healing. At short and medium term, NABIHEAL will end up with at least two innovative multifunctional wound healing biomaterials, using affordable EU-based manufacturing technologies. At long term, NABIHEAL could become a game-change alternative to silver in wound healing dressings. A consortium composed by 5 SME and 9 academic institutions, with expertise in wound healing product development, evaluation and commercialization, nanotechnology, safety, and regulatory will join forces to address this ambitious objective.
Campo scientifico
Parole chiave
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Meccanismo di finanziamento
RIA - Research and Innovation actionCoordinatore
28029 Madrid
Spagna