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MICRObiome Biobanking (RI) Enabler

Descripción del proyecto

Metodologías optimizadas para la conservación de microbiomas: mantenimiento de la composición y la funcionalidad

Los microbiomas son comunidades de microorganismos que incluyen bacterias, arqueas, protistas, hongos y microalgas, además de sus elementos estructurales, metabolitos, moléculas de señalización, elementos genéticos móviles y las condiciones ambientales circundantes. Son esenciales para mantener los ecosistemas y la salud de plantas, animales y seres humanos. El equipo del proyecto MICROBE, financiado con fondos europeos, cooperará con infraestructuras de investigación para crear y desarrollar metodologías y tecnologías que permitan el acceso a muestras de microbiomas y a datos asociados. Los objetivos del proyecto incluyen soluciones técnicas para la conservación, propagación y evaluación de la funcionalidad de los microbiomas, así como infraestructuras de datos. Además, en MICROBE se abordarán cuestiones relacionadas con la normalización, los requisitos éticos y jurídicos, así como las oportunidades comerciales.

Objetivo

"Microbiomes comprise communities of microorganisms (i.e. microbiota that includes bacteria, archaea, protists, fungi and microalgae) and their ""theatre of activity"" (i.e. structural elements, metabolites, signal molecules, mobile genetic elements, as well as surrounding environmental conditions). Microbiomes play a key role in maintaining life on Earth by providing a range of essential ecosystem services and are indispensable for the health of plants, animals and humans. Thus, there is a wide consensus that by harnessing microbiome functions society would be better placed to tackle global challenges such as food security, health and wellbeing, food waste management, and climate change mitigation. To facilitate the science necessary to achieve key advances in microbiome research, methodologies and technologies to capture or create, ensure stable long-term maintenance, and experimentally perturb microbiomes are required. Research infrastructures currently lack optimized methodologies and technologies to preserve and provide access to microbiome samples and massive amounts of associated data MICROBE is designed to address these issues by building upon and connecting: (1) technical solutions for microbiome preservation, propagation and functionality assessment, (2) novel ecological concepts (i.e. “core microbiome” and “microbial keystone taxa”), and (3) data infrastructures. In addition, MICROBE will address essential framework issues such as standardization, ethical and legal requirements and new business opportunities. Participation of relevant European research infrastructures, i.e. BBMRI-ERIC, MIRRI, ELIXIR and EMBRC-ERIC, to ensure that community needs are properly addressed and that developed solutions are efficiently taken up by the infrastructures themselves and by their user communities. Long term ambition is to ensure widespread uptake in microbiome research communities and thus support the development of novel microbiome-based applications."

Coordinador

AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
Aportación neta de la UEn
€ 1 013 846,75
Dirección
GIEFINGGASSE 4
1210 Wien
Austria

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Región
Ostösterreich Wien Wien
Tipo de actividad
Research Organisations
Enlaces
Coste total
€ 1 013 846,75

Participantes (9)