Description du projet
Combler les manquements de la préparation aux pandémies
Le bouleversement mondial qu’a provoqué la pandémie de COVID-19 a révélé une lacune critique dans notre capacité à réagir rapidement aux pathogènes émergents. Il est indispensable d'accélérer la recherche, d'améliorer la surveillance et de développer des contre-mesures efficaces contre les menaces épidémiques et pandémiques. Les lacunes actuelles des réponses mondiales, européennes et nationales nous ont rendus vulnérables à la nature imprévisible des agents pathogènes, tels que l'insaisissable agent pathogène X. Dans ce contexte, le projet LEAPS, financé par l'UE, se propose de déployer une stratégie proactive, validée par les parties prenantes, de surveillance génomique afin d'améliorer la préparation et la réponse aux pandémies. LEAPS entend, par le biais d’une approche pluridisciplinaire, révolutionner la préparation à la pandémie aux niveaux national et européen, en proposant une plateforme d'apprentissage stratégique et d'adaptation pour les futures mise en œuvre.
Objectif
The COVID-19 pandemic has exposed a global need for accelerating research, improving surveillance, and efficiently developing countermeasures against pathogens with epidemic and pandemic potential. LEAPS aims to demonstrate the value and feasibility of a pro-active policy-supporting strategy for genomic surveillance and for pandemic preparedness and response, by delivering a system-wide stakeholder-validated proof of concept, validated in 4 EU countries, of a learning and adaptive European pandemic preparedness system against pathogen X.
LEAPS will fill the gaps observed by global, EU (HERA) and national stakeholders in pandemic response by demonstrating the feasibility of combining genomic One Health surveillance, with genomic epidemiologic modeling for detailed pathogen understanding and precise public health intervention design. LEAPS formalizes dynamic health emergency threat assessment linked to the initiation of governance mechanisms to enable timely decisions in crucial, early stages of an outbreak. LEAPS will develop protocols and models for accelerated medical countermeasure development, availability and accessibility. Based on resulting highly effective intervention strategies, timely countermeasure access and governance mechanisms, model-based policy support is proposed to health authorities for effective, implementable, stakeholder co-created epidemic response scenarios against pathogen X. Scenarios are evaluated on health, socio-economic, and sustainability impact.
LEAPS brings together a unique multidisciplinary team with optimal complementary expertise and experience. LEAPS will interact regularly with medical and scientific communities, HERA and health authorities in order to disseminate relevant and accessible information, and during non-emergency periods LEAPS will validate a roadmap for large-scale implementation of LEAPS methodology by EU level, and national authorities and stakeholders in an ecosystem of interlinked actors.
Champ scientifique
Mots‑clés
Programme(s)
Régime de financement
HORIZON-RIA - HORIZON Research and Innovation ActionsCoordinateur
3000 Leuven
Belgique