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CORDIS - EU research results
CORDIS

Personalized Drug Response: IMplementation and Evaluation in CKD

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Draft Communication and dissemination strategy (opens in new window)

Communication and dissemination strategy, including Stakeholder Network strategy and reports

Project Website (opens in new window)

PRIME-CKD website will be launched

Completed communication tools (opens in new window)

Completed communication tools to educate patients, which should include response score cards, lead REGIONH

Data Management plan (opens in new window)

Data Management Plan defining the standards, templates, data management and quality procedures to be used throughout the project lifecycle

Publications

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations (opens in new window)

Author(s): Renske Johanna Grupstra, Viktoriia Starokozhko, Elisabeth Bakker, Anna Maria Gerdina Pasmooij, Peter Gerardus Maria Mol
Published in: Clinical Pharmacology & Therapeutics, 2026, ISSN 0009-9236
Publisher: Wiley
DOI: 10.1002/CPT.70229

Proteins and signalling pathways targeted by dapagliflozin and finerenone: Insights from <scp>DAPA</scp> ‐ <scp>CKD</scp> and <scp>FIGARO</scp> ‐ <scp>DKD</scp> (opens in new window)

Author(s): Mark André de la Rambelje, Adriaan A. Voors, Peter J. Greasley, Mario Berger, Hiddo J. L. Heerspink
Published in: Diabetes, Obesity and Metabolism, Issue 28, 2025, ISSN 1462-8902
Publisher: Wiley
DOI: 10.1111/DOM.70193

420-P: Baseline Risk and Longitudinal Changes in KidneyIntelX Scores and Their Association with Kidney Outcomes in the CANVAS and CREDENCE Trials (opens in new window)

Author(s): ERIK MOEDT, STEVEN COCA, FERGUS FLEMING, HIDDO L. HEERSPINK
Published in: Diabetes, Issue 74, 2025, ISSN 0012-1797
Publisher: American Diabetes Association
DOI: 10.2337/DB25-420-P

Nature Medicine (opens in new window)

Author(s): Daniel E. Coral; Femke Smit; Ali Farzaneh; Alexander Gieswinkel; Juan Fernandez Tajes; Thomas Sparsø; Carl Delfin; Pierre Bauvin; Kan Wang; Marinella Temprosa; Diederik De Cock; Jordi Blanch; José Manuel Fernández-Real; Rafael Ramos; M. Kamran Ikram; Maria F. Gomez; Maryam Kavousi; Marina Panova-Noeva; Philipp S. Wild; Carla van der Kallen; Michiel Adriaens; Marleen van Greevenbroek; Ilja Arts; Carel Le Roux; Fariba Ahmadizar; Timothy M. Frayling; Giuseppe N. Giordano; Ewan R. Pearson; Paul W. Franks
Published in: Nature Medicine, 2024, ISSN 1078-8956
Publisher: Nature Publishing Group
DOI: 10.1038/S41591-024-03299-7

Clinical and Translational Science (opens in new window)

Author(s): Elisabeth Bakker, Viktoriia Starokozhko, Jet W. M. Kraaijvanger, Hiddo J. L. Heerspink, Peter G. M. Mol
Published in: Clinical and Translational Science, 2023, ISSN 1752-8054
Publisher: Wiley Periodicals LLC
DOI: 10.1111/cts.13641

Reporting guidelines for precision medicine research of clinical relevance: the BePRECISE checklist (opens in new window)

Author(s): Siew S. Lim, Zhila Semnani-Azad, Mario L. Morieri, Ashley H. Ng, Abrar Ahmad, Hugo Fitipaldi, Jacqueline Boyle, Christian Collin, John M. Dennis, Claudia Langenberg, Ruth J. F. Loos, Melinda Morrison, Michele Ramsay, Arun J. Sanyal, Naveed Sattar, Marie-France Hivert, Maria F. Gomez, Jordi Merino, Deirdre K. Tobias, Michael I. Trenell, Stephen S. Rich, Jennifer L. Sargent, Paul W. Franks
Published in: Nature Medicine, Issue 30, 2024, ISSN 1078-8956
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41591-024-03033-3

Sodium glucose co-transporter 2 inhibition increases epidermal growth factor expression and improves outcomes in patients with type 2 diabetes (opens in new window)

Author(s): Taha Sen, Wenjun Ju, Viji Nair, Matthias Kretzler, Petter Bjornstad, Hiddo J.L. Heerspink
Published in: Kidney International, 2023, ISSN 0085-2538
Publisher: Elsevier Inc
DOI: 10.1016/j.kint.2023.07.007

Clinical Trials for Kidney Disease in the Era of Personalized Medicine (opens in new window)

Author(s): Hiddo J.L. Heerspink and Matthias Kretzler
Published in: Journal of the American Society of Nephrology, 2024, ISSN 1046-6673
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/ASN.0000000000000412

Derivation and independent validation of <scp>kidneyintelX</scp> .dkd: A prognostic test for the assessment of diabetic kidney disease progression (opens in new window)

Author(s): Girish N. Nadkarni, Sharon Stapleton, Dipti Takale, Katherine Edwards, Kara Moran, Gohar Mosoyan, Michael K. Hansen, Michael J. Donovan, Hiddo J. L. Heerspink, Fergus Fleming, Steven G. Coca
Published in: Diabetes, Obesity and Metabolism, Issue 25, 2025, ISSN 1462-8902
Publisher: Wiley
DOI: 10.1111/DOM.15273

Protein profiles and associated biological pathways among different aetiologies of chronic kidney disease: new insights from DAPA-CKD (opens in new window)

Author(s): M André de la Rambelje, Iris E Beldhuis, Hiddo J L Heerspink, Peter J Greasley, Rasmus Agren, Ann Hammarstedt, C David Sjöström, Adriaan A Voors, Niels Jongs
Published in: Nephrology Dialysis Transplantation, 2025, ISSN 0931-0509
Publisher: Oxford University Press (OUP)
DOI: 10.1093/NDT/GFAF180

Bioanalysis (opens in new window)

Author(s): A. Mireille A. Wessels; Lenneke A. T. Junier; Daan Touw; Jasper Stevens
Published in: Bioanalysis, Issue 17, 2025, ISSN 1757-6180
Publisher: Future Science
DOI: 10.1080/17576180.2025.2462429

Metabolite-enhanced normothermic machine perfusion improves kidney transplant viability (opens in new window)

Author(s): Jan Czogalla; Fabian Hausmann; Simon Lagies; Sydney E. Gies; Sabrina Christiansen; Nico Kaiser; Fabian Haas; Yusuke Okabayashi; Dominik Kylies; Smilla Hofmann; Rossana Franzin; Niklas Sabra; Sarah Bouari; Yitian Fang; Gisela Ambagtsheer; Ilka Edenhofer; Silvia Chilla; Anne K. Mühlig; Marina Zimmermann; Milagros N. Wong; Takashi Yokoo; Oliver Kretz; Maja Lindenmeyer; Florian Grahammer; Martin J. Hoogduijn; Ron de Bruin; Malte Kuehl; Sonja Hänzelmann; Bernd Kammerer; Loreto Gesualdo; Stefan Bonn; Robert C. Minnee; Tobias B. Huber; Victor G. Puelles
Published in: JCI Insight, Issue 10, 2025, ISSN 2379-3708
Publisher: American Society for Clinical Investigation
DOI: 10.1172/JCI.INSIGHT.190185

Project Website

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