Personalized Drug Response: IMplementation and Evaluation in CKD

Project Information

PRIME-CKD

Grant agreement ID: 101095146

DOI

10.3030/101095146

EC signature date 30 November 2022

Start date 1 January 2023

End date 31 December 2027

Funded under

• Health

Total cost

€ 9 242 241,01

EU contribution

€ 9 242 240,51

Coordinated by

ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (1)

Draft Communication and dissemination strategy

Communication and dissemination strategy, including Stakeholder Network strategy and reports

Websites, patent fillings, videos etc. (2)

Project Website

PRIME-CKD website will be launched

Completed communication tools

Completed communication tools to educate patients, which should include response score cards, lead REGIONH

Data Management Plan (1)

Data Management plan

Data Management Plan defining the standards, templates, data management and quality procedures to be used throughout the project lifecycle

Publications

Peer reviewed articles (9)

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

Author(s): Renske Johanna Grupstra, Viktoriia Starokozhko, Elisabeth Bakker, Anna Maria Gerdina Pasmooij, Peter Gerardus Maria Mol
Published in: Clinical Pharmacology & Therapeutics, 2026, ISSN 0009-9236
Publisher: Wiley
DOI: 10.1002/CPT.70229

Proteins and signalling pathways targeted by dapagliflozin and finerenone: Insights from <scp>DAPA</scp> ‐ <scp>CKD</scp> and <scp>FIGARO</scp> ‐ <scp>DKD</scp>

Author(s): Mark André de la Rambelje, Adriaan A. Voors, Peter J. Greasley, Mario Berger, Hiddo J. L. Heerspink
Published in: Diabetes, Obesity and Metabolism, Issue 28, 2025, ISSN 1462-8902
Publisher: Wiley
DOI: 10.1111/DOM.70193

Nature Medicine

Author(s): Daniel E. Coral; Femke Smit; Ali Farzaneh; Alexander Gieswinkel; Juan Fernandez Tajes; Thomas Sparsø; Carl Delfin; Pierre Bauvin; Kan Wang; Marinella Temprosa; Diederik De Cock; Jordi Blanch; José Manuel Fernández-Real; Rafael Ramos; M. Kamran Ikram; Maria F. Gomez; Maryam Kavousi; Marina Panova-Noeva; Philipp S. Wild; Carla van der Kallen; Michiel Adriaens; Marleen van Greevenbroek; Ilja Arts; Carel Le Roux; Fariba Ahmadizar; Timothy M. Frayling; Giuseppe N. Giordano; Ewan R. Pearson; Paul W. Franks
Published in: Nature Medicine, 2024, ISSN 1078-8956
Publisher: Nature Publishing Group
DOI: 10.1038/S41591-024-03299-7

Clinical and Translational Science

Author(s): Elisabeth Bakker, Viktoriia Starokozhko, Jet W. M. Kraaijvanger, Hiddo J. L. Heerspink, Peter G. M. Mol
Published in: Clinical and Translational Science, 2023, ISSN 1752-8054
Publisher: Wiley Periodicals LLC
DOI: 10.1111/cts.13641

Reporting guidelines for precision medicine research of clinical relevance: the BePRECISE checklist

Author(s): Siew S. Lim, Zhila Semnani-Azad, Mario L. Morieri, Ashley H. Ng, Abrar Ahmad, Hugo Fitipaldi, Jacqueline Boyle, Christian Collin, John M. Dennis, Claudia Langenberg, Ruth J. F. Loos, Melinda Morrison, Michele Ramsay, Arun J. Sanyal, Naveed Sattar, Marie-France Hivert, Maria F. Gomez, Jordi Merino, Deirdre K. Tobias, Michael I. Trenell, Stephen S. Rich, Jennifer L. Sargent, Paul W. Franks
Published in: Nature Medicine, Issue 30, 2024, ISSN 1078-8956
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41591-024-03033-3

Sodium glucose co-transporter 2 inhibition increases epidermal growth factor expression and improves outcomes in patients with type 2 diabetes

Author(s): Taha Sen, Wenjun Ju, Viji Nair, Matthias Kretzler, Petter Bjornstad, Hiddo J.L. Heerspink
Published in: Kidney International, 2023, ISSN 0085-2538
Publisher: Elsevier Inc
DOI: 10.1016/j.kint.2023.07.007

Protein profiles and associated biological pathways among different aetiologies of chronic kidney disease: new insights from DAPA-CKD

Author(s): M André de la Rambelje, Iris E Beldhuis, Hiddo J L Heerspink, Peter J Greasley, Rasmus Agren, Ann Hammarstedt, C David Sjöström, Adriaan A Voors, Niels Jongs
Published in: Nephrology Dialysis Transplantation, 2025, ISSN 0931-0509
Publisher: Oxford University Press (OUP)
DOI: 10.1093/NDT/GFAF180

Bioanalysis

Author(s): A. Mireille A. Wessels; Lenneke A. T. Junier; Daan Touw; Jasper Stevens
Published in: Bioanalysis, Issue 17, 2025, ISSN 1757-6180
Publisher: Future Science
DOI: 10.1080/17576180.2025.2462429

Metabolite-enhanced normothermic machine perfusion improves kidney transplant viability

Author(s): Jan Czogalla; Fabian Hausmann; Simon Lagies; Sydney E. Gies; Sabrina Christiansen; Nico Kaiser; Fabian Haas; Yusuke Okabayashi; Dominik Kylies; Smilla Hofmann; Rossana Franzin; Niklas Sabra; Sarah Bouari; Yitian Fang; Gisela Ambagtsheer; Ilka Edenhofer; Silvia Chilla; Anne K. Mühlig; Marina Zimmermann; Milagros N. Wong; Takashi Yokoo; Oliver Kretz; Maja Lindenmeyer; Florian Grahammer; Martin J. Hoogduijn; Ron de Bruin; Malte Kuehl; Sonja Hänzelmann; Bernd Kammerer; Loreto Gesualdo; Stefan Bonn; Robert C. Minnee; Tobias B. Huber; Victor G. Puelles
Published in: JCI Insight, Issue 10, 2025, ISSN 2379-3708
Publisher: American Society for Clinical Investigation
DOI: 10.1172/JCI.INSIGHT.190185

Other (1)

Project Website