Personalized Drug Response: IMplementation and Evaluation in CKD

Project Information

PRIME-CKD

Grant agreement ID: 101095146

DOI

10.3030/101095146

EC signature date 30 November 2022

Start date 1 January 2023

End date 31 December 2027

Funded under

• Health

Total cost

€ 9 242 241,01

EU contribution

€ 9 242 240,51

Coordinated by

ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (1)

Draft Communication and dissemination strategy

Communication and dissemination strategy, including Stakeholder Network strategy and reports

Websites, patent fillings, videos etc. (1)

Project Website

PRIME-CKD website will be launched

Data Management Plan (1)

Data Management plan

Data Management Plan defining the standards, templates, data management and quality procedures to be used throughout the project lifecycle

Publications

Peer reviewed articles (8)

Proteins and signalling pathways targeted by dapagliflozin and finerenone: Insights from <scp>DAPA</scp> ‐ <scp>CKD</scp> and <scp>FIGARO</scp> ‐ <scp>DKD</scp>

Author(s): Mark André de la Rambelje, Adriaan A. Voors, Peter J. Greasley, Mario Berger, Hiddo J. L. Heerspink
Published in: Diabetes, Obesity and Metabolism, Issue 28, 2025, ISSN 1462-8902
Publisher: Wiley
DOI: 10.1111/DOM.70193

420-P: Baseline Risk and Longitudinal Changes in KidneyIntelX Scores and Their Association with Kidney Outcomes in the CANVAS and CREDENCE Trials

Author(s): ERIK MOEDT, STEVEN COCA, FERGUS FLEMING, HIDDO L. HEERSPINK
Published in: Diabetes, Issue 74, 2025, ISSN 0012-1797
Publisher: American Diabetes Association
DOI: 10.2337/DB25-420-P

Clinical and Translational Science

Author(s): Elisabeth Bakker, Viktoriia Starokozhko, Jet W. M. Kraaijvanger, Hiddo J. L. Heerspink, Peter G. M. Mol
Published in: Clinical and Translational Science, 2023, ISSN 1752-8054
Publisher: Wiley Periodicals LLC
DOI: 10.1111/cts.13641

Reporting guidelines for precision medicine research of clinical relevance: the BePRECISE checklist

Author(s): Siew S. Lim, Zhila Semnani-Azad, Mario L. Morieri, Ashley H. Ng, Abrar Ahmad, Hugo Fitipaldi, Jacqueline Boyle, Christian Collin, John M. Dennis, Claudia Langenberg, Ruth J. F. Loos, Melinda Morrison, Michele Ramsay, Arun J. Sanyal, Naveed Sattar, Marie-France Hivert, Maria F. Gomez, Jordi Merino, Deirdre K. Tobias, Michael I. Trenell, Stephen S. Rich, Jennifer L. Sargent, Paul W. Franks
Published in: Nature Medicine, Issue 30, 2024, ISSN 1078-8956
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41591-024-03033-3

Sodium glucose co-transporter 2 inhibition increases epidermal growth factor expression and improves outcomes in patients with type 2 diabetes

Author(s): Taha Sen, Wenjun Ju, Viji Nair, Matthias Kretzler, Petter Bjornstad, Hiddo J.L. Heerspink
Published in: Kidney International, 2023, ISSN 0085-2538
Publisher: Elsevier Inc
DOI: 10.1016/j.kint.2023.07.007

Clinical Trials for Kidney Disease in the Era of Personalized Medicine

Author(s): Hiddo J.L. Heerspink and Matthias Kretzler
Published in: Journal of the American Society of Nephrology, 2024, ISSN 1046-6673
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/ASN.0000000000000412

Derivation and independent validation of <scp>kidneyintelX</scp> .dkd: A prognostic test for the assessment of diabetic kidney disease progression

Author(s): Girish N. Nadkarni, Sharon Stapleton, Dipti Takale, Katherine Edwards, Kara Moran, Gohar Mosoyan, Michael K. Hansen, Michael J. Donovan, Hiddo J. L. Heerspink, Fergus Fleming, Steven G. Coca
Published in: Diabetes, Obesity and Metabolism, Issue 25, 2025, ISSN 1462-8902
Publisher: Wiley
DOI: 10.1111/DOM.15273

Protein profiles and associated biological pathways among different aetiologies of chronic kidney disease: new insights from DAPA-CKD

Author(s): M André de la Rambelje, Iris E Beldhuis, Hiddo J L Heerspink, Peter J Greasley, Rasmus Agren, Ann Hammarstedt, C David Sjöström, Adriaan A Voors, Niels Jongs
Published in: Nephrology Dialysis Transplantation, 2025, ISSN 0931-0509
Publisher: Oxford University Press (OUP)
DOI: 10.1093/NDT/GFAF180