Personalized Drug Response: IMplementation and Evaluation in CKD

Informazioni relative al progetto

PRIME-CKD

ID dell’accordo di sovvenzione: 101095146

DOI

10.3030/101095146

Data della firma CE 30 Novembre 2022

Data di avvio 1 Gennaio 2023

Data di completamento 31 Dicembre 2027

Finanziato da

• Health

Costo totale

€ 9 242 241,01

Contributo UE

€ 9 242 240,51

Coordinato da

ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (1)

Draft Communication and dissemination strategy

Communication and dissemination strategy, including Stakeholder Network strategy and reports

Websites, patent fillings, videos etc. (1)

Project Website

PRIME-CKD website will be launched

Data Management Plan (1)

Data Management plan

Data Management Plan defining the standards, templates, data management and quality procedures to be used throughout the project lifecycle

Pubblicazioni

Peer reviewed articles (8)

Proteins and signalling pathways targeted by dapagliflozin and finerenone: Insights from <scp>DAPA</scp> ‐ <scp>CKD</scp> and <scp>FIGARO</scp> ‐ <scp>DKD</scp>

Autori: Mark André de la Rambelje, Adriaan A. Voors, Peter J. Greasley, Mario Berger, Hiddo J. L. Heerspink
Pubblicato in: Diabetes, Obesity and Metabolism, Numero 28, 2025, ISSN 1462-8902
Editore: Wiley
DOI: 10.1111/DOM.70193

420-P: Baseline Risk and Longitudinal Changes in KidneyIntelX Scores and Their Association with Kidney Outcomes in the CANVAS and CREDENCE Trials

Autori: ERIK MOEDT, STEVEN COCA, FERGUS FLEMING, HIDDO L. HEERSPINK
Pubblicato in: Diabetes, Numero 74, 2025, ISSN 0012-1797
Editore: American Diabetes Association
DOI: 10.2337/DB25-420-P

Clinical and Translational Science

Autori: Elisabeth Bakker, Viktoriia Starokozhko, Jet W. M. Kraaijvanger, Hiddo J. L. Heerspink, Peter G. M. Mol
Pubblicato in: Clinical and Translational Science, 2023, ISSN 1752-8054
Editore: Wiley Periodicals LLC
DOI: 10.1111/cts.13641

Reporting guidelines for precision medicine research of clinical relevance: the BePRECISE checklist

Autori: Siew S. Lim, Zhila Semnani-Azad, Mario L. Morieri, Ashley H. Ng, Abrar Ahmad, Hugo Fitipaldi, Jacqueline Boyle, Christian Collin, John M. Dennis, Claudia Langenberg, Ruth J. F. Loos, Melinda Morrison, Michele Ramsay, Arun J. Sanyal, Naveed Sattar, Marie-France Hivert, Maria F. Gomez, Jordi Merino, Deirdre K. Tobias, Michael I. Trenell, Stephen S. Rich, Jennifer L. Sargent, Paul W. Franks
Pubblicato in: Nature Medicine, Numero 30, 2024, ISSN 1078-8956
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41591-024-03033-3

Sodium glucose co-transporter 2 inhibition increases epidermal growth factor expression and improves outcomes in patients with type 2 diabetes

Autori: Taha Sen, Wenjun Ju, Viji Nair, Matthias Kretzler, Petter Bjornstad, Hiddo J.L. Heerspink
Pubblicato in: Kidney International, 2023, ISSN 0085-2538
Editore: Elsevier Inc
DOI: 10.1016/j.kint.2023.07.007

Clinical Trials for Kidney Disease in the Era of Personalized Medicine

Autori: Hiddo J.L. Heerspink and Matthias Kretzler
Pubblicato in: Journal of the American Society of Nephrology, 2024, ISSN 1046-6673
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/ASN.0000000000000412

Derivation and independent validation of <scp>kidneyintelX</scp> .dkd: A prognostic test for the assessment of diabetic kidney disease progression

Autori: Girish N. Nadkarni, Sharon Stapleton, Dipti Takale, Katherine Edwards, Kara Moran, Gohar Mosoyan, Michael K. Hansen, Michael J. Donovan, Hiddo J. L. Heerspink, Fergus Fleming, Steven G. Coca
Pubblicato in: Diabetes, Obesity and Metabolism, Numero 25, 2025, ISSN 1462-8902
Editore: Wiley
DOI: 10.1111/DOM.15273

Protein profiles and associated biological pathways among different aetiologies of chronic kidney disease: new insights from DAPA-CKD

Autori: M André de la Rambelje, Iris E Beldhuis, Hiddo J L Heerspink, Peter J Greasley, Rasmus Agren, Ann Hammarstedt, C David Sjöström, Adriaan A Voors, Niels Jongs
Pubblicato in: Nephrology Dialysis Transplantation, 2025, ISSN 0931-0509
Editore: Oxford University Press (OUP)
DOI: 10.1093/NDT/GFAF180