Early Interception of Inflammatory-mediated Type 2 Diabetes

Informazioni relative al progetto

INTERCEPT-T2D

ID dell’accordo di sovvenzione: 101095433

DOI

10.3030/101095433

Data della firma CE 23 Novembre 2022

Data di avvio 1 Gennaio 2023

Data di completamento 31 Dicembre 2027

Finanziato da

• Health

Costo totale

€ 8 689 221,50

Contributo UE

€ 8 689 221,50

Coordinato da

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (5)

Plan for dissemination and exploitation including communication activities

Records of activities related to dissemination and exploitation that have been undertaken and those planned (report to be updated periodically).

Update Plan for dissemination and exploitation including communication activities 1

1st Update for the Plan for dissemination and exploitation including communication activities

Data management plan

DMP describing the data management life cycle for the data to be collected, processed and generated by the project (report to be updated periodically).

Update Data management plan 1

1st Update on the Data Management Plan

Project communication tools

First version of project’s website / Project leaflet distributed.

Pubblicazioni

Peer reviewed articles (9)

Explainable AI-based analysis of human pancreas sections identifies traits of type 2 diabetes

Autori: Lukas Klein, Sebastian Ziegler, Felicia Gerst, Yanni Morgenroth, Karol Gotkowski, Eyke Schöniger, Martin Heni, Nicole Kipke, Daniela Friedland, Annika Seiler, Ellen Geibelt, Hajime Yamazaki, Hans-Ulrich Häring, Silvia Wagner, Silvio Nadalin, Alfred Königsrainer, Andre L. Mihaljevic, Daniel Hartmann, Falko Fend, Daniela Aust, Jürgen Weitz, Reiner Jumpertz-von Schwartzenberg, Marius Distler, Klaus Maier-Hein, Andreas L. Birkenfeld, Susanne Ullrich, Paul F. Jäger, Fabian Isensee, Michele Solimena, Robert Wagner
Pubblicato in: Nature Communications, Numero 17, 2026, ISSN 2041-1723
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S41467-026-69295-2

Diabetes and pulmonary infection: how hyperglycaemia shapes the immune system

Autori: Christian Herder, Michael Roden & Nicolas Venteclef
Pubblicato in: Signal Transduction and Targeted Therapy, 2024, ISSN 2059-3635
Editore: epub
DOI: 10.1038/s41392-024-01784-6

Aldolase-regulated G3BP1/2+ condensates control insulin mRNA storage in beta cells

Autori: Esteban Quezada, Klaus-Peter Knoch, Jovana Vasiljevic, Annika Seiler, Akshaye Pal, Abishek Gunasekaran, Carla Münster, Daniela Friedland, Eyke Schöniger, Anke Sönmez, Pascal Roch, Carolin Wegbrod, Katharina Ganß, Nicole Kipke, Simon Alberti, Rita Nano, Lorenzo Piemonti, Daniela Aust, Jürgen Weitz, Marius Distler, Michele Solimena
Pubblicato in: The EMBO Journal, Numero 44, 2025, ISSN 1460-2075
Editore: Springer Science and Business Media LLC
DOI: 10.1038/S44318-025-00448-7

Blood Monocyte Phenotype Is A Marker of Cardiovascular Risk in Type 2 Diabetes

Autori: "Jean-Baptiste Julla # 1 2 3 4, Diane Girard # 1 2 3, Marc Diedisheim 1 2 3 5, Pierre-Jean Saulnier 6, Bao Tran Vuong 1 2 3, Camille Blériot 1 2 3, Elena Carcarino 1 2 3, Joe De Keizer 7, Lucie Orliaguet 1 2 3, Ivan Nemazanyy 1, Charline Potier 1 2 3, Kenn"
Pubblicato in: Circulation Research, 2023, ISSN 1524-4571
Editore: epub
DOI: 10.1161/CIRCRESAHA.123.322757

Post-transcriptional regulation of insulin mRNA storage by G3BP1/2+ condensates in beta cells

Autori: Esteban Quezada, Jovana Vasiljevic, Akshaye Pal, Carla Münster, Daniela Friedland, Eyke Schöniger, Anke Sönmez, Annika Seiler, Pascal Roch, Carolin Wegbrod, Katharina Ganß, Klaus-Peter Knoch, Nicole Kipke, View ORCID ProfileSimon Alberti, Rita Nano, Vie
Pubblicato in: Biorxviv, 2024, ISSN 2692-8205
Editore: epub
DOI: 10.1101/2024.05.25.595863

Aldolase-regulated G3BP1/2+ condensates control insulin mRNA storage in beta cells

Autori: Esteban Quezada; Klaus-Peter Knoch; Jovana Vasiljevic; Annika Seiler; Akshaye Pal; Abishek Gunasekaran; Carla Münster; Daniela Friedland; Eyke Schöniger; Anke Sönmez; Pascal Roch; Carolin Wegbrod; Katharina Ganß; Nicole Kipke; Simon Alberti; Rita Nano; Lorenzo Piemonti; Daniela Aust; Jürgen Weitz; Marius Distler; Michele Solimena
Pubblicato in: The EMBO Journal, 2025, ISSN 2059-3635
Editore: The EMBO Journal
DOI: 10.1038/S44318-025-00448-7

Nature Communications

Autori: Andreas Müller; Nikolai Klena; Song Pang; Leticia Elizabeth Galicia Garcia; Oleksandra Topcheva; Solange Aurrecoechea Duran; Davud Sulaymankhil; Monika Seliskar; Hassan Mziaut; Eyke Schöniger; Daniela Friedland; Nicole Kipke; Susanne Kretschmar; Carla Münster; Jürgen Weitz; Marius Distler; Thomas Kurth; Deborah Schmidt; Harald F. Hess; C. Shan Xu; Gaia Pigino; Michele Solimena
Pubblicato in: Nature Communications, 2023, ISSN 2041-1723
Editore: Nature Communications (online)
DOI: 10.1038/S41467-024-53348-5

Incidence of death and amputation in patients with a first diabetic foot ulcer: results from the CODIA cohort

Autori: Jean-Baptiste Julla, Théo Jolivet, Candice Estellat, Gaël Varoquaux, Aurélie Carlier, Jean-François Gautier, Julie Alberge, Yawa Abouleka, Audrey Bergès, Elise Liu, Judith Abecassis, Florence Tubach, Louis Potier
Pubblicato in: Diabetes & Metabolism, Numero 51, 2025, ISSN 1262-3636
Editore: Elsevier BV
DOI: 10.1016/J.DIABET.2025.101700

From Prediction to Prescription: Machine Learning and Causal Inference for the Heterogeneous Treatment Effect

Autori: Judith Abécassis, Élise Dumas, Julie Alberge, Gaël Varoquaux
Pubblicato in: Annual Review of Biomedical Data Science, Numero 8, 2025, ISSN 2574-3414
Editore: Annual Reviews
DOI: 10.1146/ANNUREV-BIODATASCI-103123-095750

Conference proceedings (1)

On the calibration of survival models with competing risks

Autori: Julie Alberge, Tristan Haugomat, Gaël Varoquaux, Judith Abécassis
Pubblicato in: Accepted in AIstats, 2026, ISSN 2640-3498
Editore: No