PHYSICS INFORMED MACHINE LEARNING-BASED PREDICTION AND REVERSION OF IMPAIRED FASTING GLUCOSE MANAGEMENT

Project Information

PRAESIIDIUM

Grant agreement ID: 101095672

DOI

10.3030/101095672

Project closed

EC signature date 11 November 2022

Start date 1 January 2023

End date 31 December 2025

Funded under

• Health

Total cost

€ 5 808 741,25

EU contribution

€ 5 808 740,00

Coordinated by

SPINDOX LABS SRL
Italy

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

Project management report 1.1

Project management report v1.1

Communication Plan for Dissemination and Exploitation

Websites, patent fillings, videos etc. (1)

Project Website

Project website

Publications

Peer reviewed articles (10)

Robust control-driven counterfactual generation for uncertain systems

Author(s): Pierluigi Francesco De Paola, Jared Miller, Alessandro Borri, Alessia Paglialonga, Fabrizio Dabbene
Published in: IFAC-PapersOnLine, Issue 59, 2025, ISSN 2405-8963
Publisher: Elsevier BV
DOI: 10.1016/J.IFACOL.2025.10.089

Understanding and Exploring the Food Preferences of Filipino School-Aged Children Through Free Drawing as a Projective Technique

Author(s): Melvin Bernardino, Nicole Sison, Jeanne Bruce, Claudio Tiribelli, Natalia Rosso
Published in: Nutrients, Issue 16, 2025, ISSN 2072-6643
Publisher: MDPI AG
DOI: 10.3390/NU16234035

The Long-Term Effects of Physical Activity on Blood Glucose Regulation: A Model to Unravel Diabetes Progression

Author(s): Pierluigi Francesco De Paola; Alessia Paglialonga; Pasquale Palumbo; Karim Keshavjee; Fabrizio Dabbene; Alessandro Borri
Published in: IEEE Control Systems Letters, 2023, ISSN 2475-1456
Publisher: IEEE
DOI: 10.1109/lcsys.2023.3290774

Signal Acquisition and Algorithm Design for Bioimpedance-Based Heart Rate Estimation from the Wrist

Author(s): Didzis Lapsa; Margus Metshein; Andrei Krivošei; Rims Janeliukstis; Olev Märtens; Atis Elsts
Published in: Applied Sciences, 2024, ISSN 2076-3417
Publisher: MDPI
DOI: 10.3390/APP14219632

Modeling the cumulative benefits of regular physical activity on type 2 diabetes progression

Author(s): Pierluigi Francesco De Paola, Alessandro Borri, Fabrizio Dabbene, Karim Keshavjee, Pasquale Palumbo, Alessia Paglialonga
Published in: Computers in Biology and Medicine, Issue 198, 2025, ISSN 0010-4825
Publisher: Elsevier BV
DOI: 10.1016/J.COMPBIOMED.2025.111194

Low-Abundance Proteomics Reveal Pleiotrophin and Fibroblast Growth Factor-21 as Biomarkers of Metabolic Dysfunction-Associated Steatohepatitis

Author(s): Melissa M. Milito, Milos Mihajlovic, Alice Mallia, Stefania Ghilardi, Claudio Tiribelli, Deborah Bonazza, Natalia Rosso, Silvia Palmisano, Cristina Banfi, Pablo J. Giraudi
Published in: International Journal of Molecular Sciences, Issue 26, 2025, ISSN 1422-0067
Publisher: MDPI AG
DOI: 10.3390/IJMS262210943

From System Models to Class Models: An In-Context Learning Paradigm

Author(s): M. Forgione, F. Pura and D. Piga
Published in: IEEE Control Systems Letters, ISSN 2475-1456
Publisher: IEEE
DOI: 10.1109/LCSYS.2023.3335036

PPG and Bioimpedance-Based Wearable Applications in Heart Rate Monitoring—A Comprehensive Review

Author(s): Didzis Lapsa; Rims Janeliukstis; Margus Metshein; Leo Selavo
Published in: Applied Sciences, 2024, ISSN 2076-3417
Publisher: MDPI
DOI: 10.3390/APP14177451

Long-Term Diabetes Prevention via Physical Activity: An Output-Feedback MPC Approach

Author(s): Pierluigi Francesco De Paola, Alessandro Borri, Alessia Paglialonga, Fabrizio Dabbene, Pasquale Palumbo
Published in: IEEE Control Systems Letters, Issue 9, 2025, ISSN 2475-1456
Publisher: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.1109/LCSYS.2025.3578031

A reduced model for the long-term effects of physical activity on type 2 diabetes

Author(s): Multerer, Lea; De Paola, Pierluigi Francesco; Lenatti, Marta; Paglialonga, Alessia; Azzimonti, Laura
Published in: Mathematical Biosciences, 2024, ISSN 2331-8422
Publisher: Elsevier
DOI: 10.1016/J.MBS.2026.109645

Conference proceedings (3)

Polynomial approximation of regions of attraction via occupation measures: an application to a biological autonomous system

Author(s): Pierluigi Francesco De Paola, Alessandro Borri, Alessia Paglialonga, Pasquale Palumbo, Fabrizio Dabbene
Published in: 2024 IEEE 20th International Conference on Automation Science and Engineering (CASE), 2024
Publisher: IEEE
DOI: 10.1109/CASE59546.2024.10711611

A Computationally Efficient Deep Learning-Based Surrogate Model of Prediabetes Progression

Author(s): Lea Multerer, Stefano Toniolo, Sandra Mitrović, Maria Concetta Palumbo, Alessandro Ravoni, Paolo Tieri, Marco Forgione, Laura Azzimonti
Published in: 2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2025
Publisher: IEEE
DOI: 10.1109/BIBM62325.2024.10822298

Multi-Input Multi-Output Dynamic Modelling of Type 2 Diabetes Progression

Author(s): Davide Simeone, Marta Lenatti, Constantino Lagoa, Karim Keshavjee, Aziz Guergachi, Fabrizio Dabbene, Alessia Paglialonga
Published in: Studies in Health Technology and Informatics, 2023
Publisher: IOS Press
DOI: 10.3233/SHTI230784

Book chapters (4)

Exploring Prediabetes Pathways Using Explainable AI on Data from Electronic Medical Records

Author(s): Console, Davide; Lenatti, Marta; Simeone, Davide; Keshavjee, Karim; Guergachi, Aziz; Mongelli, Maurizio; Paglialonga, Alessia
Published in: Studies in Health Technology and Informatics, 2024
Publisher: IOS press eBook
DOI: 10.3233/SHTI240519

A Model-Based Approach for Glucose Control via Physical Activity

Author(s): Pierluigi Francesco de Paola, Alessandro Borri, Alessia Paglialonga, Pasquale Palumbo, Fabrizio Dabbene
Published in: Studies in Health Technology and Informatics, Intelligent Health Systems – From Technology to Data and Knowledge, 2025
Publisher: IOS Press
DOI: 10.3233/SHTI250267

Physics-Informed Neural Networks for Hidden Insulin Dynamics Estimation from Glucose Data

Author(s): Lea Multerer, Manuel Acquistapace, Marco Forgione, Laura Azzimonti
Published in: Lecture Notes in Computer Science, Artificial Intelligence in Medicine, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-95841-0_53

Counterfactual Inference Using Ordinary Differential Equations to Assess the Effect of Physical Activity on Type 2 Diabetes Onset

Author(s): Marta Lenatti, Marco Zaffalon, Alessandro Antonucci, Pierluigi Francesco De Paola, Lea Multerer, Maurizio Mongelli, Alessia Paglialonga, Laura Azzimonti
Published in: Lecture Notes in Computer Science, Artificial Intelligence in Medicine, 2025
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-95838-0_21